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Fiberoptic Endoscopic Evaluation of Swallowing in Resistant Hypertensive Patients With and Without Sleep Obstructive Apnea

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Abstract

Resistant arterial hypertension (RAH) is strongly associated with obstructive sleep apnea (OSA). Individuals with OSA may have subclinical swallow impairment, diagnosed by instrumental assessments, such as videofluoroscopy and fiberoptic endoscopic evaluation of swallowing (FEES). However, few studies have evaluated this population and included a control group of individuals without OSA. To evaluate, through FEES, the swallowing characteristics of resistant hypertensive patients with and without OSA and to investigate the association between the signs of swallow impairment and OSA. This was an observational study in which individuals with RAH underwent baseline polysomnography and were diagnosed with and without OSA. All participants underwent an initial assessment with the collection of demographic characteristics and FEES. Individuals were divided into 2 groups based on the presence or absence of OSA. Seventy-nine resistant hypertensive patients were evaluated: 60 with OSA (19 with mild OSA, 21 with moderate OSA, and 20 with severe OSA) and 19 without OSA. The most prevalent swallowing differences between groups with and without OSA were piecemeal deglutition, in 61.7% and 31.6%, respectively (p = 0.022); spillage, in 58.3% and 21.1% (p = 0.005); penetration/aspiration, in 55% and 47.4% (p = 0.561); and pharyngeal residue, in 51.5% and 26.3% (p = 0.053). The prevalence of swallow impairment among the participants in this study was 58.3% and 47.4% in the groups with OSA and without OSA, respectively (p = 0.402). This study shows a high prevalence of swallow impairment both in hypertensive patients with OSA and without OSA. The characteristics of swallowing associated with hypertensive patients with OSA are spillage, piecemeal deglutition, and the onset of the pharyngeal phase in the hypopharynx.

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Authors and Affiliations

  1. M.D. Program in Internal Medicine, Department of Internal Medicine, School of Medicine, Federal University of Rio de Janeiro – UFRJ, Rua Professor Rodolpho Paulo Rocco, 255, 9º andar, sala 9E11, Ilha do Fundão, Rio de Janeiro, Rio de Janeiro, CEP: 21941-590, Brazil

    Flavia Rodrigues Ferreira, Thalyta Georgia Vieira Borges, Carla Rocha Muniz, Mariana Pinheiro Brendim & Elizabeth Silaid Muxfeldt

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  1. Flavia Rodrigues Ferreira
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  2. Thalyta Georgia Vieira Borges
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  3. Carla Rocha Muniz
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  4. Mariana Pinheiro Brendim
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  5. Elizabeth Silaid Muxfeldt
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Correspondence to Flavia Rodrigues Ferreira.

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The study was approved by the research ethics committee of Hospital Universitário Clementino Fraga Filho (HUCFF): Number 1.890.776.

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Ferreira, F.R., Borges, T.G.V., Muniz, C.R. et al. Fiberoptic Endoscopic Evaluation of Swallowing in Resistant Hypertensive Patients With and Without Sleep Obstructive Apnea. Dysphagia 37, 1247–1257 (2022). https://doi.org/10.1007/s00455-021-10380-7

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