The objective of this study is to construct a propagation curve and determine propagation velocities in young healthy adults examined using a 2.64-mm-diameter high-resolution manometry catheter with 36 circumferential sensors; to explore data reproducibility; and to determine whether the swallowing pressure (SP) propagation velocity correlated with bolus volume. Repeated measures with subjects serving as their own controls. Thirty healthy subjects (average age 25.3 years) swallowed saliva and 2, 5, and 10 mL of cold water to determine the maximum SP from the soft palate to the cervical esophagus. The SP propagation curve was obtained by plotting the duration to reach each SP peak. The SP propagation velocity was calculated for each region. These parameters were examined according to bolus size and gender. The intra-class correlation coefficient for estimating the SP propagation curves was >0.61 (i.e., highly consistent). The propagation velocity was maximal at the meso-hypopharynx and minimal at the UES and cervical esophagus. The SP propagation curve was very reproducible within any subject. Neither the water volume (with the exception of 2 and 5 mL) nor gender exerted any apparent effect on velocity in any region. However, the velocity was quite variable at the cervical esophagus.
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This study was supported by the 6th Japan society logopedics and phoniatrics research Grant in 2012 and JSPS KAKENHI, Grant No. 24592602.
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Conflict of interest
Hurwitz AL, Nelson JA, Haddad JK. Oropharyngeal dysphagia manometric and cine esophagraphic findings. Am J Dig Dis. 1975;20:313–24.CrossRefPubMedGoogle Scholar
Dodds WJ, Hogan WJ, Lydon SB, et al. Quantitation of pharyngeal motor function in normal human subjects. J Appl Physiol. 1975;39:692–6.PubMedGoogle Scholar
Fyke FE Jr, Code CF. Resting and deglutition pressures in the pharyngoesophageal region. Gastroenterology. 1955;29:24–34.PubMedGoogle Scholar
Kahrilas PJ, Logemann JA, Lin S, et al. Pharyngeal clearance during swallowing: a combined manometric and videofluoroscopic study. Gastroenterology. 1992;103:128–36.PubMedGoogle Scholar
Kahrilas PJ, Lin S, Logemann JA, et al. Deglutitive tongue action: volume accommodation and bolus propulsion. Gastroenterology. 1993;104:152–62.PubMedGoogle Scholar
Mori T. Intraluminal pressure profiles in the pharyngeal phase in both normal and abnormal subjects [in Japanese]. Nihon Jibiinkoka Gakkai Kaiho. 1992;95:1022–34.CrossRefPubMedGoogle Scholar
Matsubara K, Kumai Y, Samejima Y, et al. Swallowing pressure and pressure profiles in young healthy adults. Laryngoscope. 2014;124:711–7.CrossRefPubMedGoogle Scholar
McCulloch TM, Hoffman MR, Ciucci MR. High-resolution manometry of pharyngeal swallow pressure events associated with head turn and chin tuck. Ann Otol Rhinol Laryngol. 2010;119(6):369–76.PubMedCentralPubMedGoogle Scholar
Hoffman MR, Mielens JD, Ciucci MR, et al. High-resolution manometry of pharyngeal swallow pressure events associated with effortful swallow and the mendelsohn maneuver. Dysphagia. 2012;27:418–26.PubMedCentralCrossRefPubMedGoogle Scholar
Takasaki K, Umeki H, Enatsu K, et al. Investigation of pharyngeal swallowing function using high-resolution manometry. Laryngoscope. 2008;118:1729–32.CrossRefPubMedGoogle Scholar
Jones CA, Hammer MJ, Hoffman MR, et al. Quantifying contributions of the cricopharyngeus to upper esophageal sphincter pressure changes by means of intramuscular electromyography and high-resolution manometry. Ann Otol Rhinol Laryngol. 2014;123:174–82.PubMedCentralCrossRefPubMedGoogle Scholar