Comments on Selected Recent Dysphagia Literature
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Voice and Swallowing in Patients Enrolled in a Larynx Preservation Trial
Carrara-de Angelis E, Feher O. Barros AP, Nishimoto IN, Kowalski LP
Arch Otolaryngol Head Neck Surg 129:733–738, 2003
The main goals of larynx preservation protocols are preservation of a functional larynx with intact voice and maintenance of normal deglutition. However, few studies have addressed functional outcomes. The objective of this study was to evaluate voice and swallowing in patients enrolled in a larynx preservation protocol. Acoustic analyses of 15 patients and videofluoroscopic evaluation of 14 patients are reported. Forty-three patients with larynx or hypopharyngeal squamous cell carcinomas were treated with weekly paclitaxel 30 mg/m2 and cisplatin 20 mg/m2concurrent with radiotherapy 180-rad/day fraction to 7040 rad (70.4 Gy). Vocal analysis found normal results in one patient, mild dysphonia in 4, moderate dysphonia in 6, and severe dysphonia in 4. The mean fundamental frequency for acoustic...