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Dysphagia

, Volume 17, Issue 2, pp 147–151 | Cite as

A Prospective Assessment of the Characteristics of Dysphagia in Myasthenia Gravis

  • Angela  Colton–Hudson
  • Wilma J. Koopman
  • Taslim  Moosa
  • Dean  Smith
  • David  Bach
  • Michael  Nicolle

Fatigable muscle weakness is the clinical hallmark of the human autoimmune disease myasthenia gravis (MG). Weakness of the oropharyngeal muscles produces dysphagia, which continues to be a major source of morbidity in MG. In this study we prospectively assessed 20 patients with myasthenia gravis who described difficulties with swallowing. Videofluoroscopic assessment showed disordered swallowing in all, with abnormalities in oral, pharyngeal, and, to a lesser extent, oral preparatory phases. Of the 20 studied, 7 aspirated, most of whom did so silently. Laryngeal penetration occurred in many more patients. The characteristics of dysphagia in MG are described and compared with other neurological disorders that can produce dysphagia.

Keywords

Autoimmune Disease Neurological Disorder Muscle Weakness Prospective Assessment Preparatory Phasis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag New York Inc. 2002

Authors and Affiliations

  • Angela  Colton–Hudson
    • 1
  • Wilma J. Koopman
    • 1
  • Taslim  Moosa
    • 1
  • Dean  Smith
    • 2
  • David  Bach
    • 2
  • Michael  Nicolle
    • 1
  1. 1.Department of Clinical Neurological Sciences, London Health Sciences Centre, London, Ontario, CanadaCA
  2. 2.Department of Diagnostic Radiology and Nuclear Medicine , London Health Sciences Centre, London, Ontario, CanadaCA

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