Skip to main content

Advertisement

SpringerLink
Log in

Impact of operating conditions on performance of a novel gas double-dynamic solid-state fermentation bioreactor (GDSFB)

  • Original Paper
  • Published:
Bioprocess and Biosystems Engineering Aims and scope Submit manuscript

Abstract

A self-designed novel solid-state fermentation (SSF) bioreactor named “gas double-dynamic solid-state fermentation bioreactor (GDSFB)” showed great success in processes for the production of several valuable products. For the present study, a simple GDSFB (2 L in volume) was designed to investigate the impact of exhaust time on SSF performance. Both air pressure and vent aperture significantly influenced the exhaust time. The production of cellulase by Penicillium decumbens JUA10 was studied in this bioreactor. When the vent aperture was maintained at 0.2 cm, the highest FPA activity of 17.2 IU/g dry solid-state medium was obtained at an air pressure of 0.2 MPa (gauge pressure). When the air pressure was maintained at 0.2 MPa, a vent aperture of 0.3 cm gave the highest FPA activity of 18.0 IU/g dry solid-state medium. Further analysis revealed that the exhaust time was a crucial indicator of good performance in GDSFB.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

References

  1. Singhania RR, Sukumaran RK, Patel AK, Larroche C, Pandey A (2010) Advancement and comparative profiles in the production technologies using solid-state and submerged fermentation for microbial cellulases. Enzyme Microb Technol 46:541–549

    Article  CAS  Google Scholar 

  2. Barrios-González J (2012) Solid-state fermentation: physiology of solid medium, its molecular basis and applications. Process Biochem 47:175–185

    Article  Google Scholar 

  3. Durand A (2003) Bioreactor designs for solid state fermentation. Biochem Eng J 13:113–125

    Article  CAS  Google Scholar 

  4. Pandey A, Soccol CR, Mitchell D (2000) New developments in solid state fermentation I. Bioprocesses and products. Process Biochem 35:1153–1169

    Article  CAS  Google Scholar 

  5. Pandey A (2003) Solid-state fermentation. Biochem Eng J 13:81–84

    Article  CAS  Google Scholar 

  6. Singhaniaa RR, Patel AK, Soccolc CR, Pandey A (2009) Recent advances in solid-state fermentation. Biochem Eng J 44:13–18

    Article  Google Scholar 

  7. Gervais P, Molin P (2003) The role of water in solid-state fermentation. Biochem Eng J 13:85–101

    Article  CAS  Google Scholar 

  8. Bhargav S, Panda BP, Ali M, Javedb S (2008) Solid-state fermentation: an overview. Chem Biochem Eng Q 22:49–70

    CAS  Google Scholar 

  9. Xu FJ, Chen HZ, Li ZH (2002) Effect of periodically dynamic changes of air on cellulase production in solid-state fermentation. Enzyme Microb Technol 30:45–48

    Article  CAS  Google Scholar 

  10. Couto SR, Sanromán MA (2006) Application of solid-state fermentation to food industry—a review. J Food Eng 76:291–302

    Article  CAS  Google Scholar 

  11. Chen HZ, Xu FJ, Tian ZH, Li ZH (2002) A novel industrial-level reactor with two dynamic changes of air for solid-state fermentation. J Biosci Bioeng 93:211–214

    Article  CAS  Google Scholar 

  12. Chen HZ, Li ZH (2007) Gas dual-dynamic solid state fermentation technique and apparatus. U.S. Patent 7183074 B2

  13. Chen HZ, Xu J, Li ZH (2005) Temperature control at different bed depths in a novel solid-state fermentation system with two dynamic changes of air. Biochem Eng J 23:117–122

    Article  Google Scholar 

  14. Zhang AJ, Chen HZ, Li ZH (2005) Air pressure pulsation solid state production of alkaline protease by Bacillus pumilus 1.1625. Process Biochem 40:1547–1551

    Article  CAS  Google Scholar 

  15. Chen HZ, Li HQ (2008) The principle of artificial periodic stimulation: a novel idea for bioreactor design. In: Columbus F (ed) Biotechnology: research, technology, and applications. Nova Science Publishers, New York

    Google Scholar 

  16. Zeng W, Chen HZ (2009) Air pressure pulsation solid state fermentation of feruloyl esterase by Aspergillus niger. Bioresource Technol 100:1371–1375

    Article  CAS  Google Scholar 

  17. Sun T, Liu BH, Li ZH, Liu DM (1999) Effects of air pressure amplitude on cellulase productivity by Trichoderma viride SL-1 in periodic pressure solid state fermenter. Process Biochem 34:25–29

    Article  Google Scholar 

  18. Mo HT, Zhang XY, Li ZH (2004) Control of gas phase for enhanced cellulase production by Penicillium decumbens in solid-state culture. Process Biochem 39:1293–1297

    Article  CAS  Google Scholar 

  19. He Q, Chen HZ (2012) Pilot-scale gas double-dynamic solid-state fermentation for the production of industrial enzymes. Food Bioprocess Technol. doi:10.1007/s11947-012-0956-9

    Google Scholar 

  20. Zhao H, Zhang XY, Li ZH (2001) Effects of periodic air pressure oscillation on growth of Rhizobium leguminosarum in a solid state fermenter. Process Biochem 37:165–167

    Article  CAS  Google Scholar 

  21. Zhang ZG, Chen HZ (2010) Xanthan production on polyurethane foam and its enhancement by air pressure pulsation. Appl Biochem Biotechnol 162:2244–2258

    Article  CAS  Google Scholar 

  22. Handbook of Machine Design Editorial Board (2007) Pneumatic motion control. In: Wen BC (ed) Handbook of machine design. China Machine Press, Beijing (in Chinese)

  23. Chen HZ (1998) Overall utilization of steam-exploded straws. PhD Thesis, Institute of Chemical Metallurgy, CAS, Beijing

  24. Ghose TK (1987) Measurement of cellulase activities. Pure Appl Chem 59:257–268

    Article  CAS  Google Scholar 

  25. Nopharatana M, Howes T, Mitchell DA (1998) Modelling fungal growth on surfaces. Biotechnol Tech 12:313–318

    Article  CAS  Google Scholar 

  26. Nagel FJI, Tramper J, Bakke MSN, Rinzema A (2001) Temperature control in a continuously mixed bioreactor for solid-state fermentation. Biotechnol Bioeng 72:231–243

    Article  CAS  Google Scholar 

  27. Rathbun BL, Shuler ML (1983) Heat and mass transfer effects in static solid-substrate fermentations: design of fermentation chambers. Biotechnol Bioeng 25:929–938

    Article  CAS  Google Scholar 

Download references

Acknowledgments

Financial support to this study was provided by the National Basic Research Program of China (973 Project, No. 2011CB707401), the National High Technology Research and Development Program of China (863 Program, SS2012AA022502), the National Key Project of Scientific and Technical Supporting Program of China (No. 2011BAD22B02).

Author information

Authors and Affiliations

  1. State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, 100190, China

    Hongzhang Chen, Yanjun Li & Fujian Xu

Authors
  1. Hongzhang Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Yanjun Li
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Fujian Xu
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Hongzhang Chen.

Electronic supplementary material

Below is the link to the electronic supplementary material.

Supplementary material 1 (DOC 1961 kb)

Rights and permissions

Reprints and permissions

About this article

Cite this article

Chen, H., Li, Y. & Xu, F. Impact of operating conditions on performance of a novel gas double-dynamic solid-state fermentation bioreactor (GDSFB). Bioprocess Biosyst Eng 36, 1753–1758 (2013). https://doi.org/10.1007/s00449-013-0950-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00449-013-0950-2

Keywords

Search

Navigation