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MapsiDB: an integrated web database for type I polyketide synthases

Bioprocess and Biosystems Engineering volume 32, Article number: 723 (2009) Cite this article

Abstract

Polyketides have diverse biological activities, including pharmacological functions such as antibiotic, antitumor and agrochemical properties. They are biosynthesized from short carboxylic acid precursors by polyketide synthases (PKSs). As natural polyketide products include many clinically important drugs and the volume of data on polyketides is rapidly increasing, the development of a database system to manage polyketide data is essential. MapsiDB is an integrated web database formulated to contain data on type I polyketides and their PKSs, including domain and module composition and related genome information. Data on polyketides were collected from journals and online resources and processed with analysis programs. Web interfaces were utilized to construct and to access this database, allowing polyketide researchers to add their data to this database and to use it easily.

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Acknowledgments

This research was financially supported by Ministry of Education, Science, and Technology and Korea Industrial Technology Foundation through the Human Resource Training Project, and by Ministry of Knowledge Economy grants from the Intelligence Bioinformatics and Application Center at the Korea Research Institute of Bioscience and Biotechnology.

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Affiliations

  1. SmallSoft Co., Ltd., Jang-Dong 59-5, Yusung-Gu, Daejeon, 305-343, South Korea

    Hongseok Tae & Kiejung Park

  2. Department of Pharmaceutical Engineering, Sunmoon University, Asan, 336-708, South Korea

    Jae Kyung Sohng

Authors
  1. Hongseok Tae
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  2. Jae Kyung Sohng
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  3. Kiejung Park
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Corresponding author

Correspondence to Kiejung Park.

Additional information

MapsiDB is available at http://gate.smallsoft.co.kr:8080/pks/mapsidb.

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Tae, H., Sohng, J.K. & Park, K. MapsiDB: an integrated web database for type I polyketide synthases. Bioprocess Biosyst Eng 32, 723 (2009). https://doi.org/10.1007/s00449-008-0296-3

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  • DOI: https://doi.org/10.1007/s00449-008-0296-3

Keywords

  • Polyketide
  • PKS
  • MapsiDB
  • MAPSI
  • PKSDB