Abstract
Optimum operation and automatic control of large-scale solid substrate fermentation (SSF) bioreactors is difficult. Though advanced control algorithms can handle most challenges encountered properly, for real-time SSF processes such controllers are expensive and time consuming to design and tune. With these considerations, advanced control algorithm tests using realistic simulations appear more appropriate. We used a phenomenological process model of an SSF pilot bioreactor, coupled with a realistic noise model, to test linear model predictive controllers. We focused on the effect noise has on the performance of the control algorithms, and how to enhance performance using a combination of low-pass (Butterworth) and outlier shaving (Hampel) filters. In simulations undertaken directly with the phenomenological model it was relatively straightforward to achieve good control performance. Nevertheless, control degraded sharply when the output of the phenomenological model was contaminated with noise using our realistic noise model, even with proper signal filtering.
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References
Raimbault M (1998) General and microbiological aspects of solid substrate fermentation. Electron J Biotechnol 1:26–27
Pérez-Correa JR, Agosin E (1999). Solid state fermentation, automation of solid substrate fermentation processes. In: Flickinger M (ed) Encyclopedia of bioprocess technology: fermentation, biocatalysis and bioseparation. Wiley, New York, pp 2429–2446
Fernández MA (2001) Control automático de un bio-reactor piloto para cultivos sobre substrato sólido. PhD thesis, Universidad de Chile. 247 pp
Ryoo D, Murphy VG, Karim MN, Tengerdy RP (1991) Evaporative temperature and moisture control in a rocking reactor for solid substrate fermentation. Biotechnol Tech 5:19–24
Paján H, Pérez-Correa R, Solar I, Agosin E (1997) Multivariable model predictive control of a solid substrate pilot bioreactor: a simulation study. In: Wise D (ed) Global environmental biotechnology. Kluwer, Boston, pp 221–232
von Meien O, Luz LF, Mitchell DA, Pérez-Correa JR, Agosin E, Fernández-Fernández M, Arcas JA (2004) Control strategies for intermittently-mixed, forcefully-aerated solid-state fermentation bioreactors based on the analysis of a distributed parameter model. Chem Eng Sci 59:4493–4504
Fernández M, Pérez-Correa JR, Solar I, Agosin E (1996) Automation of a solid substrate cultivation pilot reactor. Biopro Eng 16:1–4
Araya M (2006) Estimación de parámetros y reconciliación dinámica de datos en sistemas de cultivo sobre sustrato sólido. Master’s thesis. Pontificia Universidad Católica de Chile. 190 pp
Bustamante, CR (2005) Diseño y evaluación de una estrategia de control predictivo basado en modelo no lineal para un bio-reactor piloto de cultivo sobre sustrato sólido. Master’s thesis, Universidad de Talca. 129 pp
Maciejowski JM (2002) Predictive Control with Constraints. Prentice Hall, Englewood Cliffs, 352 pp
Brosilow C, Joseph B (2002) Techniques of model-based control. Prentice Hall, Upper Saddle River, 704 pp
Ricker NL, Morari M, Bemporad A (1998). The MPC graphical user interface. Available from http://depts.washingtong.edu/control/LARRY/GUI/
Pearson RK (2006) Nonlinear empirical modeling techniques. Comput Chem Eng (in press, available online)
Khanahmadi M, Roostaazad R, Mitchell DA, Miranzadeh M, Bozorgmehri R, Safekordi A (2006) Bed moisture estimation by monitoring of air stream temperature rise in packed-bed solid-state fermentation. Chem Eng Sci 61:5654–5663
Von Meien OF, Mitchell DA (2002) A two-phase model for water and heat transfer within an intermittently-mixed solid-state fermentation bioreactor with forced aeration. Biotech Bioeng 79:416–428
Ryoo D (1990) On-line estimation and control in solid substrate fermentation. PhD thesis, Colorado State University
Acknowledgments
This work has been supported by project Fondecyt#1030325/2003. We very much appreciate the assistance of Alex Crawford in improving the style of the text and the valuable suggestions of the anonymous referees.
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Pérez-Correa, J.R., Fernández-Fernández, M. Predictive controller evaluation including non-stationary high frequency noise and outliers for batch solid substrate fermentation bioreactors. Bioprocess Biosyst Eng 29, 399–407 (2006). https://doi.org/10.1007/s00449-006-0089-5
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DOI: https://doi.org/10.1007/s00449-006-0089-5