This article discusses the separation of butanol from aqueous solutions and/or fermentation broth by adsorption. Butanol fermentation is also known as acetone butanol ethanol (ABE) or solvent fermentation. Adsorbents such as silicalite, resins (XAD-2, XAD-4, XAD-7, XAD-8, XAD-16), bone charcoal, activated charcoal, bonopore, and polyvinylpyridine have been studied. Use of silicalite appears to be the more attractive as it can be used to concentrate butanol from dilute solutions (5 to 790–810 g L−1) and results in complete desorption of butanol (or ABE). In addition, silicalite can be regenerated by heat treatment. The energy requirement for butanol recovery by adsorption–desorption processes has been calculated to be 1,948 kcal kg−1 butanol as compared to 5,789 kcal kg−1 butanol by steam stripping distillation. Other techniques such as gas stripping and pervaporation require 5,220 and 3,295 kcal kg−1 butanol, respectively.
This is a preview of subscription content, access via your institution.
Buy single article
Instant access to the full article PDF.
Tax calculation will be finalised during checkout.
Subscribe to journal
Immediate online access to all issues from 2019. Subscription will auto renew annually.
Tax calculation will be finalised during checkout.
Maddox IS (1989) The acetone-butanol-ethanol fermentation: recent progress in technology. Biotechnol Genet Eng Rev 7:189–220
Ladisch MR (1991) Fermentation-derived butanol and scenarios for its uses in energy-related applications. Enz Microbial Technol 13:280–283
Ezeji TC, Qureshi N, Blaschek HP (2004) Acetone butanol ethanol (ABE) production from concentrated substrate: reduction in substrate inhibition by fed-batch technique and product inhibition by gas stripping. Appl Microbiol Biotechnol 63:653–658
Qureshi N, Blaschek HP (2001) Evaluation of recent advances in butanol fermentation, upstream, and downstream processing. Bioprocess Biosystems Eng 24:219–226
Friedl A, Qureshi N, Maddox IS (1991) Continuous acetone-butanol-ethanol (ABE) fermentation using immobilized cells of Clostridium acetobutylicum in a packed bed reactor and integration with product removal by pervaporation. Biotechnol Bioeng 38:518–527
Qureshi N, Maddox IS, Friedl A (1992) Application of continuous substrate feeding to the ABE fermentation: Relief of product inhibition using extraction, perstraction, stripping and pervaporation. Biotechnol Prog 8:382–390
Qureshi N, Meagher MM, Huang J, Hutkins RW (2001) Acetone butanol ethanol (ABE) recovery by pervaporation using silicalite-silicone composite membrane from fed-batch reactor of Clostridium acetobutylicum. J Memb Sci 187:93–102
Groot WJ, van der Lans RGJM, Luyben KChAM (1992) Technologies for butanol recovery integrated with fermentations. Process Biochem 27:61–75
Qureshi N, Dien B, Saha BC, Ezeji TC, Blaschek HP, Cotta MA (2003) Separation of butanol from fermentation broth by pervaporation: mass flux and energy balance. In: Paper presented at the Annual Meeting of American Institute of Chemical Engineers (AIChE), San Francisco, CA, 162
Qureshi N, Cotta MA (2004) Energy requirement for butanol recovery from fermentation broth using adsorption as an alternative technique. In: Proceedings of 26th symposium on biotechnology for fuels and chemicals, Chattanooga, TN, p 116
Milestone NB, Bibby DM (1981) Concentration of alcohols by adsorption on silicalite. J Chem Technol Biotechnol 31:732–736
Das K, Soni BK, Chose, TK (1987) Static and column studies on selective adsorption-desorption of butanol. In: Proceedings 4th European congress on biotechnol 1:76–78
Meagher MM, Qureshi N, Hutkins RW (1998) Silicalite membrane and method for the selective recovery and concentration of acetone and butanol from model ABE solutions and fermentation broth. U.S. Patent 5,755,967
Groot WJ, Luyben KChAM (1986) In situ product recovery by adsorption in the butanol/isopropanol batch fermentation. Appl Microbiol Biotechnol 25:29–31
Nielsen L, Larsson M, Holst O, Mattiasson B (1987) Polymers as adsorbents for extractive bioconversions applied to the ABE-fermentation. In: Proceedings 4th European congress on biotechnol 2:293
Nielsen L, Larsson M, Holst O, Mattiasson B (1988) Adsorbents for extractive bioconversion applied to the acetone-butanol fermentation. Appl Microbiol Biotechnol 28:335–339
Yang X, Tsai G-J, Tsao GT (1994) Enhancement of in situ adsorption on the acetone-butanol fermentation by Clostridium acetobutylicum. Separation Technol 4:81–92
Maddox IS (1982) Use of silicalite for the adsorption of n-butanol from fermentation liquors. Biotechnol Lett 4:759–760
Ennis BM, Qureshi N, Maddox, IS (1987) In-line toxic product removal during solvent production by continuous fermentation using immobilized Clostridium acetobutylicum. Enzyme Microbial Technol 9:672–675
Yang X, Tsao GT (1995) Enhanced acetone-butanol fermentation using repeated fed-batch operation coupled with cell recycle by membrane and simultaneous removal of inhibitory products by adsorption. Biotechnol Bioeng 47:444–450
Holtzapple MT, Brown RF (1994) Conceptual design for a process to recover volatile solutes from aqueous solutions using silicalite. Separat Technol 4:213–229
N. Qureshi would like to thank Holly Brining and Mark Maroon for their contribution to this manuscript.
Mention of trade names of commercial products in this article/publication is solely for the purpose of providing scientific information and does not imply recommendation or endorsement by the United States Department of Agriculture.
About this article
Cite this article
Qureshi, N., Hughes, S., Maddox, I.S. et al. Energy-efficient recovery of butanol from model solutions and fermentation broth by adsorption. Bioprocess Biosyst Eng 27, 215–222 (2005). https://doi.org/10.1007/s00449-005-0402-8