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Table 2 Localization of xanthine oxidoreductase and aldehyde oxidase in diverse cell types

From: Formation and degradation of lipid droplets in human adipocytes and the expression of aldehyde oxidase (AOX)

XOR is present in:

XOR is absent from:

Alveolar epithelial cells of lactating mammary gland

Ductal epithelial cells of mammary gland

Capillary endothelial cells of

Myoepithelial cells of mammary and salivary gland

   - Small and large intestine

 

   - Heart and skeletal muscle

Endothelial cells of

   - Lung

 - Large blood vessels (arteries and veins)

   - Kidney

 - Endocardium

   - Liver

 - Capillaries of brain (gray and white matter)

   - Thymus

 - Capillaries of testis

   - Spleen

 

   - Placenta

Epithelial cells of

   - Epidermis

 - Liver

   - Choroid plexus of brain

 - Lung

   - White adipose tissue

 - Kidney

   - Arterial wall

 - Thymus

 - Epidermis

 

 - Intestine

 

Fibroblasts, adipocytes, muscle cells, nerve cells and diverse blood cells

AOX is present in:

  Visceral and subcutaneous fat depots

  Adipocytes

  Liver

  Lung

  Kidney

  Intestine

  Prostate

  Testis

  Adrenal gland

  1. Data on XOR are taken from (1) Jarasch et al., Acta Physiol. Scand (1986) Suppl. 548: 39–46. Data on AOX are taken from (2) Weigert et al., FEBS Letters (2008) 582: 2965–2972. (3) Moriwaki et al., Histol Histopathol (2001) 16: 745–753. Highlighted in bold letters: adipose tissue, fat depots and adipocytes, e.g., one main focus of this manuscript. Data for XOR are taken from a table shown by Jarasch et al. (1986) and originate from bovine tissues. Localizations were confirmed also for human tissues (see Jarasch et al. 1981; Bruder et al. 1984)