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Origin of ethnic groups, linguistic families, and civilizations in China viewed from the Y chromosome

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Abstract

East Asia, geographically extending to the Pamir Plateau in the west, to the Himalayan Mountains in the southwest, to Lake Baikal in the north and to the South China Sea in the south, harbors a variety of people, cultures, and languages. To reconstruct the natural history of East Asians is a mission of multiple disciplines, including genetics, archaeology, linguistics, and ethnology. Geneticists confirm the recent African origin of modern East Asians. Anatomically modern humans arose in Africa and immigrated into East Asia via a southern route approximately 50,000 years ago. Following the end of the Last Glacial Maximum approximately 12,000 years ago, rice and millet were domesticated in the south and north of East Asia, respectively, which allowed human populations to expand and linguistic families and ethnic groups to develop. These Neolithic populations produced a strong relation between the present genetic structures and linguistic families. The expansion of the Hongshan people from northeastern China relocated most of the ethnic populations on a large scale approximately 5300 years ago. Most of the ethnic groups migrated to remote regions, producing genetic structure differences between the edge and center of East Asia. In central China, pronounced population admixture occurred and accelerated over time, which subsequently formed the Han Chinese population and eventually the Chinese civilization. Population migration between the north and the south throughout history has left a smooth gradient in north–south changes in genetic structure. Observation of the process of shaping the genetic structure of East Asians may help in understanding the global natural history of modern humans.

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References

  • AADR (2021) Allen ancient DNA resource version 44.3. https://reich.hms.harvard.edu/allen-ancient-dna-resource-aadr-downloadable-genotypes-present-day-and-ancient-dna-data. Accessed 20 Jan 2021

  • Allentoft ME, Sikora M, Sjögren K-G, Rasmussen S, Rasmussen M, Stenderup J, Damgaard PB, Schroeder H, Ahlström T, Vinner L (2015) Population genomics of bronze age Eurasia. Nature 522:167–172

    Article  CAS  PubMed  Google Scholar 

  • An ZM, Chang KC (1979) The neolithic archaeology of China a brief survey of the last thirty years. Early China 5:35–45

    Article  Google Scholar 

  • Anderson B (2006) Imagined communities: reflections on the origin and spread of nationalism. Verso Books, London

    Google Scholar 

  • Bai F, Zhang XL, Ji XP, Cao P, Feng XT, Yang RW, Peng MS, Pei SW, Fu QM (2020) Paleolithic genetic link between Southern China and Mainland Southeast Asia revealed by ancient mitochondrial genomes. J Hum Genet 65:1125–1128

  • Bergström A, McCarthy SA, Hui R, Almarri MA, Ayub Q, Danecek P, Chen Y, Felkel S, Hallast P, Kamm J (2020) Insights into human genetic variation and population history from 929 diverse genomes. Science 367:eaay5012

  • Bräuer G, Stringer C (1997) Models, polarization, and perspectives on modern human origins. Conceptual issues in modern human origins research. Aldine de Gruyter, New York, pp 191–201

    Google Scholar 

  • Chen GQ (2010) A discussion on the origin of Hongshan culture. Res China’s Front Archaeol 1:51–54

    Google Scholar 

  • Chen GQ (2012) Re-exploration on the provenance of Hongshan culture. Res China’s Front Archaeol 1:83–87

    CAS  Google Scholar 

  • Chow BS (1981) The animal remains discovered at Cishan Village, Wu’an, Hebei Province. Acta Archaeol Sin 3:339–347

    Google Scholar 

  • Clarkson C, Harris C, Li B, Neudorf CM, Roberts RG, Lane C, Norman K, Pal J, Jones S, Shipton C (2020) Human occupation of northern India spans the Toba super-eruption ~ 74,000 years ago. Nat Commun 11:1–10

    Article  CAS  Google Scholar 

  • Cui YQ (2015) Analysis of characteristic of Xinglongwa Culture Jade. J Chifeng Univ (philosophy and Social Science Chinese Edition) 36:5–10

    CAS  Google Scholar 

  • Cui YQ, Li HJ, Ning C, Zhang Y, Chen L, Zhao X, Hagelberg E, Zhou H (2013) Y Chromosome analysis of prehistoric human populations in the West Liao River Valley, Northeast China. BMC Evol Biol 13:216

    Article  PubMed  PubMed Central  Google Scholar 

  • Cui YQ, Song L, Wei D, Pang YH, Wang N, Ning C, Li CM, Feng BX, Tang WT, Li HJ, Ren YS, Zhang CC, Huang YY, Hu YW, Zhou H (2015) Identification of kinship and occupant status in Mongolian noble burials of the Yuan Dynasty through a multidisciplinary approach. Philos Trans R Soc Lond B Biol Sci 370:20130378

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • de Barros Damgaard P, Marchi N, Rasmussen S, Peyrot M, Renaud G, Korneliussen T, Moreno-Mayar JV, Pedersen MW, Goldberg A, Usmanova E (2018a) 137 ancient human genomes from across the Eurasian steppes. Nature 557:369–374

    Article  CAS  Google Scholar 

  • de Barros Damgaard P, Martiniano R, Kamm J, Moreno-Mayar JV, Kroonen G, Peyrot M, Barjamovic G, Rasmussen S, Zacho C, Baimukhanov N (2018b) The first horse herders and the impact of early Bronze Age steppe expansions into Asia. Science 360:eaar7711

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Dong Y, Li CX, Luan FS, Li ZG, Li HJ, Cui YQ, Zhou H, Malhi RS (2015) Low mitochondrial DNA diversity in an ancient population from China: insight into social organization at the Fujia Site. Hum Biol 81:71–84

    Article  Google Scholar 

  • Fan ZQ, Deng XH, Wang CC (2018) Languages and genes: comment on the origin and dispersal of Austronesian. Acad Mon 50:175–184

    Google Scholar 

  • Flegontov P, Altınışık NE, Changmai P, Rohland N, Mallick S, Adamski N, Bolnick DA, Broomandkhoshbacht N, Candilio F, Culleton BJ (2019) Palaeo-Eskimo genetic ancestry and the peopling of Chukotka and North America. Nature 570:236–240

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Fu QM, Li H, Moorjani P, Jay F, Slepchenko SM, Bondarev AA, Johnson PL, Aximu-Petri A, Prüfer K, de Filippo C (2014) Genome sequence of a 45,000-year-old modern human from western Siberia. Nature 514:445–449

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Gao SZ, Zhang Y, Wei D, Li HJ, Zhao YB, Cui YQ, Zhou H (2015) Ancient DNA reveals a migration of the ancient Di-qiang populations into Xinjiang as early as the early Bronze Age. Am J Phys Anthropol 157:71–80

    Article  PubMed  Google Scholar 

  • Gao X, Peng F, Fu QM, Li F (2017) New progress in understanding the origins of modern humans in China. Sci China Earth Sci 60:2160–2170

    Article  Google Scholar 

  • Gayden T, Cadenas AM, Regueiro M, Singh NB, Zhivotovsky LA, Underhill PA, Cavalli-Sforza LL, Herrera RJ (2007) The Himalayas as a directional barrier to gene flow. Am J Hum Genet 80:884–894

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Ge JX, Cao SJ, Wu SD (1993) Jianming zhongguo yimin shi. Fujian Renmin Chubanshe, Fuzhou, Fujian

  • Genomes Project Consortium (2015) A global reference for human genetic variation. Nature 526:68

    Article  CAS  Google Scholar 

  • Groves CP (1989) A regional approach to the problem of the origin of modern humans in Australasia. Hum Revol 1:274–285

    Google Scholar 

  • Guo DS (2017) Yu yu Tao—Zhongguo Shiqian Yu Wenhua Yanjiu Tichu de Xin Keti. Guo Da-Shun Kaogu Wenji. Liaoning People’s Publishing House, Liaoning, pp 176–180

    Google Scholar 

  • Guo J, Xu B, Li L, He G, Zhang H, Cheng HZ, Ba J, Yang X, Wei L, Hu R, Wang CC (2019) Paternal Y chromosomal genotyping reveals multiple large-scale admixtures in the formation of Lolo-Burmese-speaking populations in southwest China. Ann Hum Biol 46:581–588

    Article  PubMed  Google Scholar 

  • Hammer MF, Karafet TM, Park H, Omoto K, Harihara S, Stoneking M, Horai S (2006) Dual origins of the Japanese: common ground for hunter-gatherer and farmer Y chromosomes. J Hum Genet 51:47–58

    Article  PubMed  Google Scholar 

  • Han JY (2010) Liangzhu, Taosi and Erlitou——the evolution route of the Early Chinese civilization. Archaeology 11:9

    Google Scholar 

  • Harney É, Nayak A, Patterson N, Joglekar P, Mushrif-Tripathy V, Mallick S, Rohland N, Sedig J, Adamski N, Bernardos R (2019) Ancient DNA from the skeletons of Roopkund Lake reveals Mediterranean migrants in India. Nat Commun 10:1–10

    Article  CAS  Google Scholar 

  • Hollard C, Keyser C, Giscard PH, Tsagaan T, Bayarkhuu N, Bemmann J, Crubezy E, Ludes B (2014) Strong genetic admixture in the Altai at the Middle Bronze Age revealed by uniparental and ancestry informative markers. Forensic Sci Int Genet 12:199–207

    Article  CAS  PubMed  Google Scholar 

  • Hollard C, Zvénigorosky V, Kovalev A, Kiryushin Y, Tishkin A, Lazaretov I, Crubézy E, Ludes B, Keyser C (2018) New genetic evidence of affinities and discontinuities between bronze age Siberian populations. Am J Phys Anthropol 167:97–107

    Article  PubMed  Google Scholar 

  • Hong SB, Jin HJ, Kwak KD, Kim W (2006) Y-chromosome haplogroup O3–M122 variation in East Asia and its implications for the peopling of Korea. Genes Genom 28:1–8

    CAS  Google Scholar 

  • Huang TM (1992) Liangzhu—a late Neolithic jade-yielding culture in southeastern coastal China. Antiquity 66:75–83

    Article  Google Scholar 

  • Huang YZ, Li H (2017) Correlation between genetic structure and linguistic phylogeny in East Asia. In: Xu D, Li H (eds) Languages and genes in Northwestern China and adjacent regions. Springer, Singapore, pp 13–36

    Chapter  Google Scholar 

  • Huang DX, Wang GY, Yang QE (2006) Haplogroup diversity of 8 biallelic markers on human Y chromosome in Wuhan Han population. Chin J Forensic Med 21:13–17

    Google Scholar 

  • Huerta Sánchez E, Jin X, Bianba ZM, Peter BM, Vinckenbosch N, Liang Y, Yi X, He MZ, Somel M, Ni PX (2014) Altitude adaptation in Tibetans caused by introgression of Denisovan-like DNA. Nature 512:194–197

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • HUGO Pan-Asian SNP Consortium (2009) Mapping human genetic diversity in Asia. Science 326:1541–1545

    Article  CAS  Google Scholar 

  • Hunan Provincial Institute of Cultural Relics and Archaeology (2006) Neolithic Gaomiao site in Hongjiang City. Hunan Kaogu 7(9–15):99–100

    Google Scholar 

  • Ingman M, Kaessmann H, Pääbo S, Gyllensten U (2000) Mitochondrial genome variation and the origin of modern humans. Nature 408:708–713

    Article  CAS  PubMed  Google Scholar 

  • Järve M, Saag L, Scheib CL, Pathak AK, Montinaro F, Pagani L, Flores R, Guellil M, Saag L, Tambets K (2019) Shifts in the genetic landscape of the Western Eurasian Steppe associated with the beginning and end of the Scythian dominance. Curr Biol 29:2430–2441 (e2410)

    Article  PubMed  CAS  Google Scholar 

  • Jeong C, Ozga AT, Witonsky DB, Malmstrom H, Edlund H, Hofman CA, Hagan RW, Jakobsson M, Lewis CM, Aldenderfer MS, Di Rienzo A, Warinner C (2016) Long-term genetic stability and a high-altitude East Asian origin for the peoples of the high valleys of the Himalayan arc. Proc Natl Acad Sci USA 113:7485–7490

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Jeong C, Wilkin S, Amgalantugs T, Bouwman AS, Taylor WTT, Hagan RW, Bromage S, Tsolmon S, Trachsel C, Grossmann J (2018) Bronze Age population dynamics and the rise of dairy pastoralism on the eastern Eurasian steppe. Proc Natl Acad Sci USA 115:E11248–E11255

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Jeong C, Balanovsky O, Lukianova E, Kahbatkyzy N, Flegontov P, Zaporozhchenko V, Immel A, Wang C-C, Ixan O, Khussainova E (2019) The genetic history of admixture across inner Eurasia. Nat Ecol Evol 3:966–976

    Article  PubMed  PubMed Central  Google Scholar 

  • Jobling M, Hurles M, Tyler Smith C (2003) Human evolutionary genetics: origins, peoples & disease. Garland Science, New York

    Google Scholar 

  • Kanzawa-Kiriyama H, Kryukov K, Jinam TA, Hosomichi K, Saso A, Suwa G, Ueda S, Yoneda M, Tajima A, Shinoda K-i (2017) A partial nuclear genome of the Jomons who lived 3000 years ago in Fukushima, Japan. J Hum Genet 62:213–221

    Article  CAS  PubMed  Google Scholar 

  • Karafet T, Xu L, Du R, Wang W, Feng S, Wells R, Redd AJ, Zegura SL, Hammer MF (2001) Paternal population history of East Asia: sources, patterns, and microevolutionary processes. Am J Hum Genet 69:615–628

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Karafet TM, Hallmark B, Cox MP, Sudoyo H, Downey S, Lansing JS, Hammer MF (2010) Major east–west division underlies Y chromosome stratification across Indonesia. Mol Biol Evol 27:1833–1844

    Article  CAS  PubMed  Google Scholar 

  • Kayser M, Choi Y, van Oven M, Mona S, Brauer S, Trent RJ, Suarkia D, Schiefenhövel W, Stoneking M (2008) The impact of the Austronesian expansion: evidence from mtDNA and Y chromosome diversity in the Admiralty Islands of Melanesia. Mol Biol Evol 25:1362–1374

    Article  CAS  PubMed  Google Scholar 

  • Ke YH, Su B, Xiao JH, Chen H, Huang W, Chen Z, Chu JY, Tan JZ, Jin L, Lu DR (2001) Y-chromosome haplotype distribution in Han Chinese populations and modern human origin in East Asians. Sci China Ser C Life Sci 44:225–232

    Article  CAS  Google Scholar 

  • Kim W, Yoo TK, Kim SJ, Shin DJ, Tyler-Smith C, Jin HJ, Kwak KD, Kim ET, Bae Y-S (2007) Lack of association between Y-chromosomal haplogroups and prostate cancer in the Korean population. PLoS ONE 2:e172

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Kim K, Brenner CH, Mair VH, Lee KH, Kim JH, Gelegdorj E, Batbold N, Song YC, Yun HW, Chang EJ (2010) A western Eurasian male is found in 2000-year-old elite Xiongnu cemetery in Northeast Mongolia. Am J Phys Anthropol 142:429–440

    Article  PubMed  Google Scholar 

  • Kutanan W, Kampuansai J, Brunelli A, Ghirotto S, Pittayaporn P, Ruangchai S, Schroder R, Macholdt E, Srikummool M, Kangwanpong D, Hubner A, Arias L, Stoneking M (2018) New insights from Thailand into the maternal genetic history of Mainland Southeast Asia. Eur J Hum Genet 26:898–911

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Kutanan W, Kampuansai J, Srikummool M, Brunelli A, Ghirotto S, Arias L, Macholdt E, Hübner A, Schröder R, Stoneking M (2019) Contrasting paternal and maternal genetic histories of Thai and Lao populations. Mol Biol Evol 36:1490–1506

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Lane CS, Chorn BT, Johnson TC (2013) Ash from the Toba supereruption in Lake Malawi shows no volcanic winter in East Africa at 75 ka. Proc Natl Acad Sci USA 110:8025–8029

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Lazaridis I, Patterson N, Mittnik A, Renaud G, Mallick S, Kirsanow K, Sudmant PH, Schraiber JG, Castellano S, Lipson M (2014) Ancient human genomes suggest three ancestral populations for present-day Europeans. Nature 513:409–413

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Li H (2005) Genetic structure of austro-tai populations. Dissertation, Fudan University

  • Li HJ (2012) Y-chromosome genetic diversity of the ancient northern chinese populations. Dissertation, Jilin University

  • Li H (2018) As ilustrações mais simples da evolução humana. Ásia Associação de Estados de Humanidade e Natureza, Macau

  • Li TJ (2019) Genomic study of the ancient populations from the period of YangShao to LongShan culture in Central Plain. Dissertation, Jilin University

  • Li H, Jin WL (2020) Human origin and migration. Shanghai Science and Technology Education Publishing House, Shanghai

    Google Scholar 

  • Li H, Pan WY, Wen B, Yang NN, Jin JZ, Jin L, Lu DR (2003) Origin of Hakka and Hakkanese: a genetics analysis. Yi Chuan Xue Bao 30:873–880

    CAS  PubMed  Google Scholar 

  • Li H, Huang Y, Mustavich LF, Zhang F, Tan JZ, Wang LE, Qian J, Gao MH, Jin L (2007) Y chromosomes of prehistoric people along the Yangtze River. Hum Genet 122:383–388

    Article  PubMed  Google Scholar 

  • Li H, Wen B, Chen SJ, Su B, Pramoonjago P, Liu YF, Pan SL, Qin ZD, Liu WH, Cheng X, Yang N, Li X, Tran D, Lu D, Hsu MT, Deka R, Marzuki S, Tan CC, Jin L (2008) Paternal genetic affinity between Western Austronesians and Daic populations. BMC Evol Biol 8:146

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Li DN, Sun YT, Lu Y, Mustavich LF, Ou CY, Zhou ZJ, Li SL, Jin L, Li H (2010b) Genetic origin of Kadai-speaking Gelong people on Hainan island viewed from Y chromosomes. J Hum Genet 55:462–468

    Article  PubMed  Google Scholar 

  • Li CX, Li HJ, Cui YQ, Xie CZ, Cai DW, Li WY, Mair VH, Xu Z, Zhang QC, Abuduresule I, Jin L, Zhu H, Zhou H (2010a) Evidence that a West-East admixed population lived in the Tarim Basin as early as the early Bronze Age. BMC Biol 8:15

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Li HJ, Zhang Y, Zhao YB, Zhou H (2013) Ancient DNA and Kinship-based Burial Patterns at Han-Jin Dynasty Taojiazhai Site, Qinghai Province, China. Asian Archaeol 2:116–125

    Google Scholar 

  • Li JW, Zeng W, Zhang Y, Ko AM, Li CX, Zhu H, Fu QM, Zhou H (2017) Ancient DNA reveals genetic connections between early Di-Qiang and Han Chinese. BMC Evol Biol 17:239

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Li JW, Zhang Y, Zhao YB, Chen YZ, Ochir A, Sarenbilige ZhuH, Zhou H (2018) The genome of an ancient Rouran individual reveals an important paternal lineage in the Donghu population. Am J Phys Anthropol 166:895–905

    Article  PubMed  Google Scholar 

  • Li JW, Cai DW, Zhang Y, Zhu H, Zhou H (2020) Ancient DNA reveals two paternal lineages C2a1a1b1a/F3830 and C2b1b/F845 in past nomadic peoples distributed on the Mongolian Plateau. Am J Phys Anthropol 172:402–411

    Article  PubMed  Google Scholar 

  • Li YQ, Yang YC (2019) The excavation of zone III of the xiao nanshan site in raohe county, Heilongjiang in 2015. Kaogu 8:3–20

  • Liao SY (2015) Genetic study on the paternal origin and prehistoric migration of Austro-Asiatic speaking populations. Dissertation, Anhui University

  • Lin YW, Chia-Ling Hsu L, Kuo PL, Huang WJ, Chiang HS, Yeh SD, Hsu TY, Yu YH, Hsiao KN, Cantor RM (2007) Partial duplication at AZFc on the Y chromosome is a risk factor for impaired spermatogenesis in Han Chinese in Taiwan. Hum Mutat 28:486–494

    Article  CAS  PubMed  Google Scholar 

  • Lipson M, Cheronet O, Mallick S, Rohland N, Oxenham M, Pietrusewsky M, Pryce TO, Willis A, Matsumura H, Buckley H (2018) Ancient genomes document multiple waves of migration in Southeast Asian prehistory. Science 361:92–95

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Liu L (2005) The Chinese Neolithic: trajectories to early states. Cambridge University Press

    Book  Google Scholar 

  • Liu M (2016) Ancient DNA research on the human remains from Dabaoshan in Inner Mongolia, China. Dissertation, Jilin University

  • Liu W, Martinón Torres M, Cai YJ, Xing S, Tong HW, Pei SW, Sier MJ, Wu XH, Edwards RL, Cheng H (2015) The earliest unequivocally modern humans in southern China. Nature 526:696–699

    Article  CAS  PubMed  Google Scholar 

  • Lkhagvasuren G, Shin H, Lee SE, Tumen D, Kim JH, Kim KY, Kim K, Park AJ, Lee HW, Kim MJ, Choi J, Choi JH, Min NY, Lee KH (2016) Molecular genealogy of a mongol queen’s family and her possible kinship with Genghis Khan. PLoS ONE 11:e0161622

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Lu HY, Zhang JP, Liu KB, Wu NQ, Li YM, Zhou KS, Ye ML, Zhang TY, Zhang HJ, Yang XY (2009) Earliest domestication of common millet (Panicum miliaceum) in East Asia extended to 10,000 years ago. Proc Natl Acad Sci USA 106:7367–7372

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Lu JN, Zhang HL, Ren Z, Wang QY, Liu YB, Li YX, He GL, Guo JX, Zhao J, Hu R, Wei LH, Chen G, Huang J, Wang CC (2020) Genome-wide analysis of unrecognised ethnic group chuanqing people revealing a close affinity with southern han chinese. Ann Hum Biol 47:465–471

  • Luojiajiao Archaeology Team (1981) Excavations at Luojiajiao Site in Tongxiang County of Zhejiang Province. Cultural Relics Publishing House, Beijing

    Google Scholar 

  • Macaulay V, Hill C, Achilli A, Rengo C, Clarke D, Meehan W, Blackburn J, Semino O, Scozzari R, Cruciani F (2005) Single, rapid coastal settlement of Asia revealed by analysis of complete mitochondrial genomes. Science 308:1034–1036

    Article  CAS  PubMed  Google Scholar 

  • Mallick S, Li H, Lipson M, Mathieson I, Gymrek M, Racimo F, Zhao MY, Chennagiri N, Nordenfelt S, Tandon A (2016) The Simons genome diversity project: 300 genomes from 142 diverse populations. Nature 538:201–206

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • McColl H, Racimo F, Vinner L, Demeter F, Gakuhari T, Moreno-Mayar JV, Van Driem G, Wilken UG, Seguin-Orlando A, De la Fuente CC (2018) The prehistoric peopling of Southeast Asia. Science 361:88–92

    Article  CAS  PubMed  Google Scholar 

  • Meyer M, Kircher M, Gansauge M-T, Li H, Racimo F, Mallick S, Schraiber JG, Jay F, Prüfer K, De Filippo C (2012) A high-coverage genome sequence from an archaic Denisovan individual. Science 338:222–226

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Mou Y, Wei Z (1978) Majiabang wenhua he liangzhu wenhua—taihu liuyu yuanshi wenhua de fenqi wenti. Wenwu 4:67–73

  • Narasimhan VM, Patterson N, Moorjani P, Rohland N, Bernardos R, Mallick S, Lazaridis I, Nakatsuka N, Olalde I, Lipson M (2019) The formation of human populations in south and central Asia. Science 365:eaat7487

  • Ning C (2017) Paleogenomic research of ancient populations from northern china. Dissertation, Jilin University

  • Ning C, Wang CC, Gao SZ, Yang Y, Zhang X, Wu XY, Zhang F, Nie ZZ, Tang YP, Robbeets M, Ma J, Krause J, Cui YQ (2019) Ancient genomes reveal yamnaya-related ancestry and a potential source of Indo-European speakers in iron age Tianshan. Curr Biol 29:2526–2532

    Article  CAS  PubMed  Google Scholar 

  • Ning C, Li TJ, Wang K, Zhang F, Li T, Wu XY, Gao SZ, Zhang QC, Zhang H, Hudson MJ, Dong GH, Wu SH, Fang YM, Liu C, Feng CY, Li W, Han T, Li R, Wei J, Zhu YG, Zhou YW, Wang CC, Fan SY, Xiong ZL, Sun ZY, Ye ML, Sun L, Wu XH, Liang FW, Cao YP, Wei XT, Zhu H, Zhou H, Krause J, Robbeets M, Jeong C, Cui YQ (2020) Ancient genomes from northern China suggest links between subsistence changes and human migration. Nat Commun 11:2700

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Pagani L, Lawson DJ, Jagoda E, Mörseburg A, Eriksson A, Mitt M, Clemente F, Hudjashov G, DeGiorgio M, Saag L (2016) Genomic analyses inform on migration events during the peopling of Eurasia. Nature 538:238–242

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Pan WY (1995) Supporting materials to Sino-Austronesian hypothesis. J Chin Linguist Monogr Ser 9:113–144

    Google Scholar 

  • Patterson N, Moorjani P, Luo Y, Mallick S, Rohland N, Zhan Y, Genschoreck T, Webster T, Reich D (2012) Ancient admixture in human history. Genetics 192:1065–1093

    Article  PubMed  PubMed Central  Google Scholar 

  • Peiros I (2011) Some thoughts on the problem of the Austro-Asiatic homeland. J Lang Relatsh 6:101–114

    Article  Google Scholar 

  • Pejros I, Shnirelman V (1998) 16 Rice in Southeast Asia: a regional interdisciplinary approach. Archaeol Lang Correl Archaeol Linguist Hypothes 2:379

    Google Scholar 

  • Peng MS, Shi NN, Yao YG, Zhang YP (2015) Caveats about interpretation of ancient chicken mtDNAs from northern China. Proc Natl Acad Sci USA 112:E1970–E1971

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Peters J, Lebrasseur O, Best J, Miller H, Fothergill T, Dobney K, Thomas RM, Maltby M, Sykes N, Hanotte O (2015) Questioning new answers regarding Holocene chicken domestication in China. Proc Natl Acad Sci USA 112:E2415–E2415

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Piazza A (1998) Towards a genetic history of China. Nature 395:637–639

    Article  CAS  Google Scholar 

  • Prüfer K, Racimo F, Patterson N, Jay F, Sankararaman S, Sawyer S, Heinze A, Renaud G, Sudmant PH, de Filippo C, Li H, Mallick S, Dannemann M, Fu QM, Kircher M, Kuhlwilm M, Lachmann M, Meyer M, Ongyerth M, Siebauer M, Theunert C, Tandon A, Moorjani P, Pickrell J, Mullikin JC, Vohr SH, Green RE, Hellmann I, Johnson PLF, Blanche H, Cann H, Kitzman JO, Shendure J, Eichler EE, Lein ES, Bakken TE, Golovanova LV, Doronichev VB, Shunkov MV, Derevianko AP, Viola B, Slatkin M, Reich D, Kelso J, Pääbo S (2013) The complete genome sequence of a Neanderthal from the Altai Mountains. Nature 505:43–49

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Raghavan M, Skoglund P, Graf KE, Metspalu M, Albrechtsen A, Moltke I, Rasmussen S, Stafford TW Jr, Orlando L, Metspalu E (2014) Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans. Nature 505:87–91

    Article  PubMed  CAS  Google Scholar 

  • Rampino MR, Self S (1992) Volcanic winter and accelerated glaciation following the Toba super-eruption. Nature 359:50–52

    Article  Google Scholar 

  • Rampino MR, Self S (1993) Bottleneck in human evolution and the Toba eruption. Science 262:1955–1955

    Article  CAS  PubMed  Google Scholar 

  • Renfrew C, Liu B (2018) The emergence of complex society in China: the case of Liangzhu. Antiquity 92:975–990

    Article  Google Scholar 

  • Rodriguez Trelles F, Tarrio R, Ayala FJ (2001) Erratic overdispersion of three molecular clocks: GPDH, SOD, and XDH. Proc Natl Acad Sci USA 98:11405–11410

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Sagart L (2005) Tai-Kadai as a subgroup of Austronesian. In: Sagart L, Blench R, Sanchez-Mazas A (eds) The peopling of East Asia. RoutledgeCurzon, London and New York, pp 177–181

  • Sagart L, Jacques G, Lai YF, Ryder RJ, Thouzeau V, Greenhill SJ, List JM (2019) Dated language phylogenies shed light on the ancestry of Sino-Tibetan. Proc Natl Acad Sci USA 116:10317–10322

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Shi H, Zhong H, Peng Y, Dong YL, Qi XB, Zhang F, Liu LF, Tan SJ, Ma RZ, Xiao CJ (2008) Y chromosome evidence of earliest modern human settlement in East Asia and multiple origins of Tibetan and Japanese populations. BMC Biol 6:45

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Shou WH, Qiao EF, Wei CY, Dong YL, Tan SJ, Shi H, Tang WR, Xiao CJ (2010) Y-chromosome distributions among populations in Northwest China identify significant contribution from Central Asian pastoralists and lesser influence of western Eurasians. J Hum Genet 55:314–322

    Article  PubMed  Google Scholar 

  • Sikora M, Pitulko VV, Sousa VC, Allentoft ME, Vinner L, Rasmussen S, Margaryan A, de Barros DP, de la Fuente C, Renaud G (2019) The population history of northeastern Siberia since the Pleistocene. Nature 570:182–188

    Article  CAS  PubMed  Google Scholar 

  • Skoglund P, Posth C, Sirak K, Spriggs M, Valentin F, Bedford S, Clark GR, Reepmeyer C, Petchey F, Fernandes D (2016) Genomic insights into the peopling of the Southwest Pacific. Nature 538:510–513

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Soares P, Rito T, Pereira L, Richards MB (2016) A genetic perspective on African prehistory. In: Jones S, Stewart B (eds) Africa from MIS 6–2. Springer, Dordrecht, pp 383–405

    Chapter  Google Scholar 

  • Stoneking M, Delfin F (2010) The human genetic history of East Asia: weaving a complex tapestry. Curr Biol 20:R188-193

    Article  CAS  PubMed  Google Scholar 

  • Su BQ, Yin WZ (1981) Guanyu kaoguxue wenhua de quxi leixing wenti. Wenwu 5:10–18

    Google Scholar 

  • Su B, Xiao JH, Underhill P, Deka R, Zhang WL, Akey J, Huang W, Shen D, Lu DR, Luo JC (1999) Y-Chromosome evidence for a northward migration of modern humans into Eastern Asia during the last Ice Age. Am J Hum Genet 65:1718–1724

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Su B, Xiao C, Deka R, Seielstad MT, Kangwanpong D, Xiao J, Lu D, Underhill P, Cavalli-Sforza L, Chakraborty R (2000) Y chromosome haplotypes reveal prehistorical migrations to the Himalayas. Hum Genet 107:582–590

    Article  CAS  PubMed  Google Scholar 

  • Sun N, Ma PC, Yan S, Wen SQ, Sun C, Du PX, Cheng HZ, Deng XH, Wang CC, Wei LH (2019) Phylogeography of Y-chromosome haplogroup Q1a1a-M120, a paternal lineage connecting populations in Siberia and East Asia. Ann Hum Biol 46:261–266

    Article  PubMed  Google Scholar 

  • Sun XF, Wen SQ, Lu CQ, Zhou BY, Curnoe D, Lu HY, Li HC, Wang W, Cheng H, Yi SW, Jia X, Du PX, Xu XH, Lu YM, Lu Y, Zheng HX, Zhang H, Sun C, Wei LH, Han F, Huang J, Edwards RL, Jin L, Li H (2021) Ancient DNA and multimethod dating confirm the late arrival of anatomically modern humans in southern China. Proc Natl Acad Sci USA 118:e2019158118

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Tajima A, Hayami M, Tokunaga K, Juji T, Matsuo M, Marzuki S, Omoto K, Horai S (2004) Genetic origins of the Ainu inferred from combined DNA analyses of maternal and paternal lineages. J Hum Genet 49:187–193

    Article  CAS  PubMed  Google Scholar 

  • Unterländer M, Palstra F, Lazaridis I, Pilipenko A, Hofmanová Z, Groß M, Sell C, Blöcher J, Kirsanow K, Rohland N (2017) Ancestry and demography and descendants of Iron Age nomads of the Eurasian Steppe. Nat Commun 8:1–10

    Article  Google Scholar 

  • Wang CC, Li H (2013) Inferring human history in East Asia from Y chromosomes. Investig Genet 4:11

    Article  PubMed  PubMed Central  Google Scholar 

  • Wang W, Wise C, Baric T, Black ML, Bittles AH (2003) The origins and genetic structure of three co-resident Chinese Muslim populations: the Salar, Bo’an and Dongxiang. Hum Genet 113:244–252

    Article  PubMed  Google Scholar 

  • Wang CC, Huang YZ, Yu XE, Chen C, Jin L, Li H (2016) Agriculture driving male expansion in neolithic time. Sci Sin Vitae 46:468–474

    Article  Google Scholar 

  • Wang LX, Lu Y, Zhang C, Wei LH, Yan S, Huang YZ, Wang CC, Mallick S, Wen SQ, Jin L, Xu SH, Li H (2018b) Reconstruction of Y-chromosome phylogeny reveals two neolithic expansions of Tibeto-Burman populations. Mol Genet Genom 293:1293–1300

    Article  CAS  Google Scholar 

  • Wang CZ, Shi Ms, Li H (2018a) The origin of Daur from the perspective of molecular anthropology. J North Minzu Univ 143:110–117

  • Wang MG, Zou X, Yeh HY, Wang Z, Liu Y, Liu J, Wang F, Yao HB, Chen PY, Tao RY (2020) Peopling of Tibet Plateau and multiple waves of admixture of Tibetans inferred from both modern and ancient genome-wide data. bioRxiv. https://doi.org/10.1101/2020.07.03.185884

    Article  PubMed  PubMed Central  Google Scholar 

  • Wang CC, Yeh HY, Popov AN, Zhang HQ, Matsumura H, Sirak K, Cheronet O, Kovalev A, Rohland N, Kim AM, Bernardos R, Tumen D, Zhao J, Liu YC, Liu JY, Mah M, Mallick S, Wang K, Zhang Z, Adamski N, Broomandkhoshbacht N, Callan K, Culleton BJ, Eccles L, Lawson AM, Michel M, Oppenheimer J, Stewardson K, Wen S, Yan S, Zalzala F, Chuang R, Huang CJ, Shiung CC, Nikitin YG, Tabarev AV, Tishkin AA, Lin S, Sun ZY, Wu XM, Yang TL, Hu X, Chen L, Du H, Bayarsaikhan J, Mijiddorj E, Erdenebaatar D, Iderkhangai TO, Myagmar E, Kanzawa Kiriyama H, Nishino M, Ki S, Shubina OA, Guo JX, Deng QY, Kang L, Li DW, Li DN, Lin R, Cai WW, Shrestha R, Wang LX, Wei LH, Xie GM, Yao HB, Zhang MF, He GL, Yang XM, Hu R, Robbeets M, Schiffels S, Kennett DJ, Jin L, Li H, Krause J, Pinhasi R, Reich D (2020) The genomic formation of human populations in East Asia. bioRxiv. https://doi.org/10.1101/2020.03.25.004606

    Article  PubMed  PubMed Central  Google Scholar 

  • Wei LH, Huang YZ, Yan S, Wen SQ, Wang LX, Du PX, Yao DL, Li SL, Yang YJ, Jin L, Li H (2017) Phylogeny of Y-chromosome haplogroup C3b–F1756, an important paternal lineage in Altaic-speaking populations. J Hum Genet 62:915–918

    Article  CAS  PubMed  Google Scholar 

  • Wen B, Li H, Lu DR, Song XF, Zhang F, He YG, Li F, Gao Y, Mao XY, Zhang L, Qian J, Tan JZ, Jin JZ, Huang W, Deka R, Su B, Chakraborty R, Jin L (2004) Genetic evidence supports demic diffusion of Han culture. Nature 431:302–305

    Article  CAS  PubMed  Google Scholar 

  • Wong EH, Khrunin A, Nichols L, Pushkarev D, Khokhrin D, Verbenko D, Evgrafov O, Knowles J, Novembre J, Limborska S (2017) Reconstructing genetic history of Siberian and Northeastern European populations. Genome Res 27:1–14

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Wu XZ (2006) Evidence of multiregional human evolution hypothesis from China. Quat Sci 26:706–709

    Google Scholar 

  • Xia ZY, Yan S, Wang CC, Zheng HX, Zhang F, Liu YC, Yu G, Yu BX, Shu LL, Jin L (2019) Inland-coastal bifurcation of southern East Asians revealed by Hmong-Mien genomic history. bioRxiv. https://doi.org/10.1101/730903

    Article  Google Scholar 

  • Xiang H, Gao JQ, Yu BQ, Zhou H, Cai DW, Zhang YW, Chen XY, Wang X, Hofreiter M, Zhao XB (2014) Early Holocene chicken domestication in northern China. Proc Natl Acad Sci USA 111:17564–17569

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Xie CZ, Li CX, Cui YQ, Zhang QC, Fu YQ, Zhu H, Zhou H (2007) Evidence of ancient DNA reveals the first European lineage in Iron Age Central China. Proc Biol Sci 274:1597–1601

    CAS  PubMed  PubMed Central  Google Scholar 

  • Xu BY, Guo JX, Huang Y, Chen XY, Deng XH, Wang CC (2019) The paternal genetic structure of Jingpo and Dai in southwest China. Ann Hum Biol 46:279–283

    Article  PubMed  Google Scholar 

  • Yan WM (1979) The new discoveries of early Neolithic culture in the Yellow River basin. Archaeology 1:45–50

    Google Scholar 

  • Yan S, Wang CC, Zheng HX, Wang W, Qin ZD, Wei LH, Wang Y, Pan XD, Fu WQ, He YG, Xiong LJ, Jin WF, Li SL, An Y, Li H, Jin L (2014) Y chromosomes of 40% Chinese descend from three Neolithic super-grandfathers. PLoS ONE 9:e105691

    Article  PubMed  PubMed Central  Google Scholar 

  • Yang MA, Gao X, Theunert C, Tong H, Aximu-Petri A, Nickel B, Slatkin M, Meyer M, Pääbo S, Kelso J (2017) 40,000-year-old individual from Asia provides insight into early population structure in Eurasia. Curr Biol 27:3202–3208 (e3209)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Yang MA, Fan XC, Sun B, Chen CY, Lang JF, Ko YC, Tsang CH, Chiu HL, Wang TY, Bao QC, Wu XH, Hajdinjak M, Ko AMS, Ding MY, Cao P, Yang RW, Liu F, Nickel B, Dai QY, Feng XT, Zhang LZ, Sun CK, Ning C, Zeng W, Zhao YS, Zhang M, Gao X, Cui YQ, Reich D, Stoneking M, Fu QM (2020) ancient DNA indicates human population shifts and admixture in northern and southern china. Science 369:282–288

    Article  CAS  PubMed  Google Scholar 

  • Yu H, Spyrou MA, Karapetian M, Shnaider S, Radzevičiūtė R, Nägele K, Neumann GU, Penske S, Zech J, Lucas M (2020) Paleolithic to Bronze Age Siberians reveal connections with first Americans and across Eurasia. Cell 181:1232–1245 (e1220)

    Article  CAS  PubMed  Google Scholar 

  • Yuan JP (2010) Shilun Zhongguo Zaoqi Wengming de Chansheng—Yi Hunan Chengtoushan Diqu Gudai Wengminghua Jincheng Weili. Cult Relics Cent China 5(22–27):32

    Google Scholar 

  • Zhang XM, Liao SY, Qi XB, Liu JW, Kampuansai J, Zhang H, Yang ZH, Serey B, Sovannary T, Bunnath L, Seang Aun H, Samnom H, Kangwanpong D, Shi H, Su B (2015) Y-chromosome diversity suggests southern origin and Paleolithic backwave migration of Austro-Asiatic speakers from eastern Asia to the Indian subcontinent. Sci Rep 5:15486

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Zhang Y, Li JW, Zhao YB, Wu XY, Li HJ, Yao L, Zhu H, Zhou H (2017) Genetic diversity of two Neolithic populations provides evidence of farming expansions in North China. J Hum Genet 62:199–204

    Article  CAS  PubMed  Google Scholar 

  • Zhang Y, Wu XY, Li JW, Li HJ, Zhao YB, Zhou H (2018) The Y-chromosome haplogroup C3*-F3918, likely attributed to the Mongol Empire, can be traced to a 2500-year-old nomadic group. J Hum Genet 63:231–238

    Article  CAS  PubMed  Google Scholar 

  • Zhang Y, Lei XY, Chen HY, Zhou H, Huang S (2018) Ancient DNAs and the Neolithic Chinese super-grandfather Y haplotypes. bioRxiv. https://doi.org/10.1101/487918

    Article  Google Scholar 

  • Zhang MH, Yan S, Pan WY, Jin L (2019) Phylogenetic evidence for Sino-Tibetan origin in northern China in the Late Neolithic. Nature 569:112–115

    Article  CAS  PubMed  Google Scholar 

  • Zhao ZJ (2010) New data and new issues for the study of origin of rice agriculture in China. Archaeol Anthropol Sci 2:99–105

    Article  Google Scholar 

  • Zhao H (2017) Liangzhu de Guojia Xingtai. China Cult Herit 3:24–30

    Google Scholar 

  • Zhao YB, Li HJ, Cai DW, Li CX, Zhang QC, Zhu H, Zhou H (2010) Ancient DNA from nomads in 2500-year-old archeological sites of Pengyang, China. J Hum Genet 55:215–218

    Article  CAS  PubMed  Google Scholar 

  • Zhao Q, Pan SL, Qin ZD, Cai XY, Lu Y, Xu JS, Yin RX, Li SL, Jin L, Li H (2010) The Minz Zhuang of Napo Country, Guangxi: legacy of the Thai-Lao Migration South. Commun Contemp Anthropol 4:22–26

    Article  Google Scholar 

  • Zhao YB, Li HJ, Li SN, Yu CC, Gao SZ, Xu Z, Jin L, Zhu H, Zhou H (2011) Ancient DNA evidence supports the contribution of Di-Qiang people to the han Chinese gene pool. Am J Phys Anthropol 144:258–268

    Article  PubMed  Google Scholar 

  • Zhao YB, Zhang Y, Li HJ, Cui YQ, Zhu H, Zhou H (2014) Ancient DNA evidence reveals that the Y chromosome haplogroup Q1a1 admixed into the Han Chinese 3,000 years ago. Am J Hum Biol 26:813–821

    Article  PubMed  Google Scholar 

  • Zhao YB, Zhang Y, Zhang QC, Li HJ, Cui YQ, Xu Z, Jin L, Zhou H, Zhu H (2015) Ancient DNA reveals that the genetic structure of the northern Han Chinese was shaped prior to 3,000 years ago. PLoS ONE 10:e0125676

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Zhong H, Shi H, Qi XB, Xiao CJ, Jin L, Ma RZ, Su B (2010) Global distribution of Y-chromosome haplogroup C reveals the prehistoric migration routes of African exodus and early settlement in East Asia. J Hum Genet 55:428–435

    Article  PubMed  Google Scholar 

  • Zhong H, Shi H, Qi XB, Duan ZY, Tan PP, Jin L, Su B, Ma RZ (2011) Extended Y chromosome investigation suggests postglacial migrations of modern humans into East Asia via the northern route. Mol Biol Evol 28:717–727

    Article  CAS  PubMed  Google Scholar 

  • Zhou R, An L, Wang X, Shao W, Lin G, Yu W, Yi L, Xu S, Xu J, Xie X (2007) Testing the hypothesis of an ancient Roman soldier origin of the Liqian people in northwest China: a Y-chromosome perspective. J Hum Genet 52:584–591

    Article  PubMed  Google Scholar 

  • Zhou R, Yang D, Zhang H, Yu W, An L, Wang X, Li H, Xu J, Xie X (2008) Origin and evolution of two Yugur sub-clans in Northwest China: a case study in paternal genetic landscape. Ann Hum Biol 35:198–211

    Article  PubMed  Google Scholar 

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Funding

This work was supported by B&R Joint Laboratory of Eurasian Anthropology (18490750300), the National Key R&D Program of China (2020YFE0201600), and the National Natural Science Foundation of China (91731303, 31671297). The European Research Council project (ERC-2019-AdG-TRAM-883700).

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  1. MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, 200438, China

    Xueer Yu & Hui Li

  2. Shanxi Academy of Advanced Research and Innovation, Fudan-Datong Institute of Chinese Origin, Datong, 037006, China

    Xueer Yu & Hui Li

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Yu, X., Li, H. Origin of ethnic groups, linguistic families, and civilizations in China viewed from the Y chromosome. Mol Genet Genomics 296, 783–797 (2021). https://doi.org/10.1007/s00438-021-01794-x

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