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Unique pattern of R-gene variation within populations in Arabidopsis

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Abstract

An understanding of the variation pattern in disease resistance (R) genes is essential for its use in breeding programs aimed at neutralizing the threat of pathogens. Although the variation between populations is well known, there is little research about R-gene variation patterns within populations. Here, we investigate the polymorphism at three R-gene loci of 39 individual plants from nine populations of Arabidopsis thaliana. Our data suggest that alleles of each locus from individuals within a local population were either nearly identical, or highly diverse as ones between populations. The vast majority (92.5%) of within-population variation was shared globally, with high levels of allelic diversity (up to 11.7%) and abundant diverse-alleles. This unique pattern of within-population variation at R-loci suggests that individual plants within a population had the great potential to maintain a high level of globally-shared polymorphisms, and that the diversifying selection was the major force maintaining such polymorphisms. Consequently, the shared-polymorphism became recyclable for new R-genes, as the corresponding avirulence re-emerges in pathogen populations.

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Acknowledgments

We thank Joy Bergelson for providing DNA of A. thaliana accessions and A. lyrata. This study was supported by NSFC (30570987 and 30470122) and Pre-program for NBRPC (2005CCA02100) to D. T. or J. Q. C.

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Authors and Affiliations

  1. State Key Laboratory of Pharmaceutical Biotechnology, Department of Biology, Nanjing University, Nanjing, 210093, China

    Jing Ding, Zhiqiang Jing, Jian-Qun Chen & Dacheng Tian

  2. College of Life Sciences, Zhongkai University of Agriculture and Technology, Guangzhou, 510225, China

    Weili Zhang

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  1. Jing Ding
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  2. Weili Zhang
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  3. Zhiqiang Jing
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  4. Jian-Qun Chen
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  5. Dacheng Tian
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Corresponding authors

Correspondence to Jian-Qun Chen or Dacheng Tian.

Additional information

Communicated by S. Hohmann.

Nucleotide sequence data reported are available in the GenBank databases under the accession numbers EF368054-EF368158.

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Ding, J., Zhang, W., Jing, Z. et al. Unique pattern of R-gene variation within populations in Arabidopsis. Mol Genet Genomics 277, 619–629 (2007). https://doi.org/10.1007/s00438-007-0213-5

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