Skip to main content

Immunocytochemical localization of antigens recognized by asymptomatic microfilaremic patient's antisera in microfilariae of Wuchereria bancrofti

Abstract.

Ultrathin sections of microfilariae of Wuchereria bancrofti embedded in hydrophilic resin were incubated with sera from patients, using antisera from asymptomatic microfilaremic patients with different microfilarial densities [1–100 microfilariae (mf)/ml, 101–500 mf/ml, >1,000 mf/ml]. All groups studied showed reactivity against relevant epitopes in all tissues of microfilariae of W. bancrofti, instead of being localized in a specific nematode region, although the number of colloidal per square micron was inversely proportional to the microfilaremia. Such results confirm data obtained by other authors and indicate a possible role for the humoral response in the mechanism for the destruction of circulating microfilariae.

This is a preview of subscription content, access via your institution.

Author information

Affiliations

Authors

Additional information

Electronic Publication

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Alves, .L., Brayner, .F., Silva, .L. et al. Immunocytochemical localization of antigens recognized by asymptomatic microfilaremic patient's antisera in microfilariae of Wuchereria bancrofti . Parasitol Res 87, 1050–1055 (2001). https://doi.org/10.1007/s004360100455

Download citation

Keywords

  • Ultrathin Section
  • Humoral Response
  • Immunocytochemical Localization
  • Relevant Epitope
  • Microfilarial Density