Abstract
Population genetic data on helminths are scarce and it is important to fine tune analyses of these data, the interpretation of which is based on between-(F st) and within-(F is) population variability. Several computer programs are available and confidence intervals of each index are based on different procedures. These programs (Genetix, Diploid, Genepop) were compared with a classical program (Biosys-1) using a large set of Haemonchus contortus isozyme data. The results were identical for all softwares for large differences when natural populations were studied (F st>0.25 and F is>0.15 or <−0.15). When small F st were investigated in laboratory-reared populations, the significance of differences was often related to the software used. As a rule of thumb, it is suggested that at least two out of three software packages (based on different calculation procedures) should give similar results before differences are validated.
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Received: 8 March 1999 / Accepted: 27 April 1999
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Bentounsi, B., Cabaret, J. Analysis of helminth genetic data: comparative examples with Haemonchus contortus isozymes using exact tests or resampling procedures. Parasitol Res 85, 855–857 (1999). https://doi.org/10.1007/s004360050645
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DOI: https://doi.org/10.1007/s004360050645