Abstract
Cases of sarcoptic mange in the wildlife population have been increasing around the world in recent years. In this study, we report the first case of severe sarcoptic mange in two Andean foxes (Lycalopex culpaeus) and molecularly analyze the collected mites. The National Forestry and Wildlife Service of Lima, Peru, found an adult male Andean fox in the province of Callao in August 2022. The veterinarians decided to euthanize the fox due to the severity of the mange. In August 2023, an adult male Andean fox was found dead in the province of Huaral by veterinarians. Both foxes were sent to the veterinary school in Lima for necropsy. Skin samples from different body zones were digested in buffer lysis, and mites were detected in the tissue samples. A morphological diagnosis identified the mites as Sarcoptes scabiei. The mites from both foxes had the same nuclear (ITS2) and mitochondrial (cox1) genetic marker sequences as the S. scabiei sequences from dogs, vicunas, Andean foxes, and water buffalos recorded in GenBank. Unlike ITS2, phylogenetic analysis of S. scabiei cox1 showed host-related nucleotide sequence polymorphisms. Future molecular studies of S. scabiei from different hosts and localities will be necessary to better understand the transmission of this disease in Andean foxes.
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References
Amer S, El Wahab TA, MetwalyAel N, Ye J, Roellig D, Feng Y, Xiao L (2014) Preliminary molecular characterizations of Sarcoptes scaibiei (Acari: Sarcoptidae) from farm animals in Egypt. PLoS One 9:e94705. https://doi.org/10.1371/journal.pone.0094705
Astorga F, Carver S, Almberg ES, Sousa GR, Wingfield K, Niedringhaus KD, Van Wick P, Rossi L, Xie Y, Cross P, Angelone S, Gortazar C, Escobar LE (2018) International meeting on sarcoptic mange in wildlife, June 2018, Blacksburg, Virginia, USA. Parasit Vectors 11:449. https://doi.org/10.1186/s13071-018-3015-1
AVMA (2020) AVMA guidelines for the euthanasia of animals, 2020 ed. Schaumburg, IL, USA.
Botten L, Ash A, Jackson B (2022) Characterising a sarcoptic mange epizootic in quenda (Isoodon fusciventer). Int J Parasitol Parasites Wildl 18:172–179. https://doi.org/10.1016/j.ijppaw.2022.04.010
de Almeida J, Leal CA, de Melo RP, de Albuquerque PP, Pedrosa C, Zermiani F, de Farias R, Mota R (2018) Co-Infection by Sarcoptes scabiei and Microsporum gypseum in Free-Ranging Crab-Eating fox, Cerdocyon thous (Linnaeus, 1766). Braz Arch Biol Technol 61:e18160508. https://doi.org/10.1590/1678-4324-2018160508
Deem SL, Noss AJ, Cuellar RL, Villarroel R, Linn MJ, Forrester DJ (2002) Sarcoptic mange in free-ranging pampas foxes in the Gran Chaco, Bolivia. J Wildl Dis 38:625–628. https://doi.org/10.7589/0090-3558-38.3.625
DíazLuque JA, Müller H, González L, Berkunsky I (2014) Clinical signs suggestive of mange infestation in a free-ranging maned wolf (Chrysocyon brachyurus) in the Moxos savannahs of Beni, Bolivia. Mastozool Neotrop 21:135–138
Escobar LE, Carver S, Cross PC, Rossi L, Almberg ES, Yabsley MJ, Niedringhaus KD, Van Wick P, Dominguez-Villegas E, Gakuya F, Xie Y, Angelone S, Gortazar C, Astorga F (2022) Sarcoptic mange: An emerging panzootic in wildlife. Transbound Emerg Dis 69:927–942. https://doi.org/10.1111/tbed.14082
Fain A (1968) Etude de la variabilité de Sarcoptes scabiei avec une révision des Sarcoptidae. Acta Zool Pathol Antverp 47:1–196
Fiori F, de Paula RC, Navas-Suarez PE, Boulhosa RLP, Dias RA (2023) The sarcoptic mange in Maned wolf (Chrysocyon brachyurus): mapping an emerging disease in the largest South American canid. Pathogens 12.
Gomez-Puerta LA, Olazabal J, Taylor CE, Cribillero NG, Lopez-Urbina MT, Gonzalez AE (2013) Sarcoptic mange in vicuna (Vicugna vicugna) population in Peru. Vet Rec 173:269. https://doi.org/10.1136/vr.101320
Gomez-Puerta LA, Pacheco JI, Angulo-Tisoc JM, Garcia W, Castillo H, Lopez-Urbina MT, Gonzalez AE (2021) Prevalence and molecular characterization of Sarcoptes scabiei from vicunas (Vicugna vicugna) from Southern Peruvian Andes. Parasitology 149:581–586. https://doi.org/10.1017/S0031182021001931
Guzman JA, D’Elia G, Ortiz JC (2009) Variación geográfica del zorro Lycalopex culpaeus (Mammalia, Canidae) en Chile: implicaciones taxonómicas. Rev Biol Trop 57:421–432
Hahn A (2019) Zoo and wild mammal formulary. John Wiley & Sons Inc, NJ, USA
Krantz GW, Walter DE (2009) A manual of acarology, 3rd edn. Texas Tech University Press, Lubbock, Tex
Kumar S, Stecher G, Li M, Knyaz C, Tamura K (2018) MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms. Mol Biol Evol 35:1547–1549. https://doi.org/10.1093/molbev/msy096
Montecino-Latorre D, Napolitano C, Briceño C, Uhart MM (2020) Sarcoptic mange: An emerging threat to Chilean wild mammals? Perspect Ecol Conserv 18:267–276. https://doi.org/10.1016/j.pecon.2020.09.007
Novaro AJ (1997) Pseudalopex culpaeus. Mamm Species 558:1–8
Old JM, Sengupta C, Narayan E, Wolfenden J (2018) Sarcoptic mange in wombats-A review and future research directions. Transbound Emerg Dis 65:399–407. https://doi.org/10.1111/tbed.12770
Pacheco V, Graham-Angeles L, Diaz Peña SR, Hurtado CM, Ruelas D, Cervantes Zevallos OK, Serrano Villavicencio JE (2020) Diversidad y distribución de los mamíferos del Perú por departamentos y ecorregiones I: Didelphimorphia, Paucituberculata, Sirenia, Cingulata, Pilosa, Primates, Lagomorpha, Eulipotyphla, Carnivora, Perissodactyla y Artiodactyla. Rev Peru Biol 27:289–328. https://doi.org/10.15381/rpb.v27i3.18356
Pence DB, Ueckermann E (2002) Sarcoptic manage in wildlife. Rev Sci Tech 21:385–398
Rojas-Sereno Z, Abbott RC, Hynes K, Bunting E, Hurst J, Heerkens S, Hanley B, Hollingshead N, Martin P, Schuler K (2022) Occurrence of mange in American black bears (Ursus americanus) in New York State, USA. J Wildl Dis 58:847–858. https://doi.org/10.7589/JWD-D-22-00010
Romero F, Espinoza A, Sallaberry-Pincheira N, Napolitano C (2019) A five-year retrospective study on patterns of casuistry and insights on the current status of wildlife rescue and rehabilitation centers in Chile. Rev Chil De Hist Nat 92:1–10. https://doi.org/10.1186/s40693-019-0086-0
Sosa FE, Bertoni EA, Micheloud JF, Vallejo DMNM, Olmos LH, Florin-Christensen M, Romero SR (2022) Occurrence of sarcoptic mange in free-ranging vicuñas (Vicugna vicugna) of the Andean high plateau region of Argentina. Parasitol Res 121:1587–1595. https://doi.org/10.1007/s00436-022-07506-7
Tamura K (1992) Estimation of the number of nucleotide substitutions when there are strong transition-transversion and G+C-content biases. Mol Biol Evol 9:678–687. https://doi.org/10.1093/oxfordjournals.molbev.a040752
Tantaleán M, Mendoza L, Riofrío F (2007) El zorro Andino, Pseudalopes culpaeus, un nuevo huésped para Corynosoma obtuscens (Acanthocephala) en el Perú. Rev Peru Biol 14:51–52
Teodoro TGW, Lima PA, Stehling PC, Oliveira IM, Varaschin MS, Wouters F, Wouters ATB (2018) Sarcoptic mange (Sarcoptes scabiei) in wild canids (Cerdocyon thous). Pesq Vet Bras 38(7):1444–1448. https://doi.org/10.1590/1678-5150-PVB-5700
Thomson P, Carreno N, Nunez A (2023) Main mites associated with dermatopathies present in dogs and other members of the Canidae family. Open Vet J 13:131–142. https://doi.org/10.5455/OVJ.2023.v13.i2.1
Verdugo C, Espinoza A, Moroni M, Valderrama R, Hernandez C (2016) Sarcoptic mange in a South American gray fox (chilla fox; Lycalopex griseus), Chile. J Wildl Dis 52:738–741. https://doi.org/10.7589/2015-07-177
Villalba-Briones R, Barros-Diaz C, Gallo-Perez A, Blasco-Carlos M, Molineros EB (2022a) First description of sarcoptic mange in a wild coati (Nasua narica), in Ecuador, and cooccurrence of canine distemper virus. Rev Bras Parasitol Vet 31:e012421. https://doi.org/10.1590/S1984-29612022002
Villalba-Briones R, Molineros EB, Monros JS (2022b) First report of Sarcoptes scabiei parasitism (Sarcoptiformes: Sarcoptidae) in Lycalopes sechurae (Mammalia: Carnivora). Rev Bras Parasitol Vet 31:e005022. https://doi.org/10.1590/S1984-29612022036
Walton SF, Dougall A, Pizzutto S, Holt D, Taplin D, Arlian LG, Morgan M, Currie BJ, Kemp DJ (2004) Genetic epidemiology of Sarcoptes scabiei (Acari: Sarcoptidae) in northern Australia. Int J Parasitol 34:839–849. https://doi.org/10.1016/j.ijpara.2004.04.002
Zahler M, Essig A, Gothe R, Rinder H (1999) Molecular analyses suggest monospecificity of the genus Sarcoptes (Acari: Sarcoptidae). Int J Parasitol 29:759–766. https://doi.org/10.1016/s0020-7519(99)00034-x
Zaldivar S (1991) Zooparasitos de interes veterinario en el Peru. Maijosa, Lima, Peru
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L.A.G.P. Sample collection, molecular analysis, writing – original draft, writing- Reviewing and Editing. J.J.V., M.A., J.M.G., and W.R.A.: Sample collection, writing – original draft. H.C.: Writing- Reviewing and Editing. All authors read and approved the final manuscript.
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This study was included in the research protocol approved by the Research Ethics Committee for Experimentation in Wildlife at the Forest and Wildlife Service of Peru (SERFOR) (018–2018-MINAGRI-SERFOR-DGGSPFFS).
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Gomez-Puerta, L.A., Jara-Vila, J., Anampa, M. et al. Molecular characterization of Sarcoptes scabiei causing severe mange in two Andean foxes (Lycalopex culpaeus) from Peru. Parasitol Res 123, 97 (2024). https://doi.org/10.1007/s00436-024-08122-3
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DOI: https://doi.org/10.1007/s00436-024-08122-3