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The complete mitochondrial genomes of Gnathostoma doloresi from China and Japan

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Abstract

Gnathostoma doloresi is one of the neglected pathogens causing gnathostomiasis. Although this zoonotic parasite leads to significant socioeconomic concerns globally, little is known of its genetics and systematics. In the present study, we sequenced and characterized the complete mitochondrial (mt) genomes of G. doloresi isolates from China and Japan. The lengths of the mt genomes of the G. doloresi China and Japan isolates are 13,809 and 13,812 bp, respectively. Both mt genomes encode 36 genes, including 12 protein-coding genes (PCGs), 2 ribosomal RNA genes, and 22 transfer RNA genes. The gene order, transcription direction, and genome content are identical with its congener G. spinigerum. Phylogenetic analyses based on concatenated amino acid sequences of 12 PCGs by Bayesian inference (BI) indicated that G. doloresi are closely related to G. spinigerum. Our data provide an invaluable resource for studying the molecular epidemiology, phylogenetics, and population genetics of Gnathostoma spp. and should have implications for further studies of the diagnosis, prevention, and control of gnathostomiasis in humans and animals.

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Acknowledgments

This work was supported by the International Science and Technology Cooperation Program of China (Grant No. 2013DFA31840).

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Authors and Affiliations

  1. College of Animal Science and Technology, Anhui Agricultural University, Hefei, Anhui Province, 230036, China

    Miao-Miao Sun, Qian-Ming Xu & Xing-Quan Zhu

  2. State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province, 730046, China

    Miao-Miao Sun, Jun Ma, Guo-Hua Liu & Xing-Quan Zhu

  3. Department of Parasitology, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan

    Hiromu Sugiyama

  4. Department of Medical Zoology, Mie University School of Medicine, Mie, 514-8507, Japan

    Katsuhiko Ando

  5. Department of Animal Experiment Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province, 510080, China

    Wen-Wen Li

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  1. Miao-Miao Sun
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  2. Jun Ma
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Correspondence to Guo-Hua Liu or Xing-Quan Zhu.

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Sun, MM., Ma, J., Sugiyama, H. et al. The complete mitochondrial genomes of Gnathostoma doloresi from China and Japan. Parasitol Res 115, 4013–4020 (2016). https://doi.org/10.1007/s00436-016-5171-6

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  • DOI: https://doi.org/10.1007/s00436-016-5171-6

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