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Human wound myiasis caused by Phormia regina and Sarcophaga haemorrhoidalis in Minia Governorate, Egypt

Parasitology Research volume 114, pages 3703–3709 (2015)Cite this article

Abstract

Myiasis is the parasitic infestation of human by the larvae (maggots) of dipterous fly that grow within the host while feeding on its tissue. Cutaneous myiasis is the most considerably encountered clinical form. Moreover, wound (traumatic) myiasis is the main clinical manifestation of cutaneous myiasis. In this research, we aimed to study the type of infesting larvae that are responsible for wound myiasis in the patients in Minia city, Egypt. Three cases of wound myiasis have been noticed among 280 patients with wounds at different parts of bodies. Two of them were diabetic patients. The third one had a history of hypertension with right side hemiplegia 2 years ago. All of them were elderly. The larvae removed from cases 1 and 3 were identified macroscopically and microscopically as the third-stage larvae of Sarcophaga haemorrhoidalis. The larvae removed from case 2 were the third-stage larvae of Phormia regina, which is very rare worldwide. In addition to the open and obsolete wound, diabetes mellitus and low socio-economic circumstances were shown to be attributed as important predisposing risk factors that led to the occurrence of myiasis in these patients.

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References

  • Ahmad AK, Abdel-Hafeez EH, Makhloof M, Abdel-Raheem EM (2011) Gastrointestinal myiasis by larvae of Sarcophaga sp. and Oestrus sp. in Egypt: report of cases, and endoscopical and morphological studies. Korean J Parasitol 49:51–57

    Article  PubMed Central  PubMed  Google Scholar 

  • Alexis JB, Mittleman RE (1988) An unusual case of Phormia regina myiasis of the scalp. Am J Clin Pathol 90:734–741

    CAS  PubMed  Google Scholar 

  • Ali-Khan FE, Ali-Khan Z (1975) A case of traumatic dermal myiasis in Quebec caused by Phormia regina (Meigen) (Diptera: Calliphoridae). Can J Zool 53:1472–1478

    CAS  Article  PubMed  Google Scholar 

  • Amendt J, Campobasso CP, Gaudry E, Reiter C, LeBlanc HN, Hall MJ (2007) Best practice in forensic entomology—standards and guidelines. Int J Legal Med 121:90–104

    Article  PubMed  Google Scholar 

  • Batista-da-Silva JA, Moya-Borja GE, Queiroz MM (2011) Factors of susceptibility of human myiasis caused by the new world screw-worm, Cochliomyia hominivorax in Sao Goncalo, Rio de Janeiro, Brazil. J Insect Sci 11:1–7

    Google Scholar 

  • Bayindir T, Cicek MT, Atambay M, Kizilay A (2012) Cutaneous myiasis in a malignant wound of the head and neck region. J Craniofac Surg 23:e19–e20

    Article  PubMed  Google Scholar 

  • Byrd JH (1998-2011) Forensic entomology: insects in legal investigations. http://www.forensicentomology.com/(8 June 2011)

  • Byrd JH, Butler JF (1998) Effects of temperature on Sarcophaga haemorrhoidalis (Diptera: Sarcophagidae) development. J Med Entomol 35:694–702

    CAS  Article  PubMed  Google Scholar 

  • Byrd JH, Castner JL (2001) Forensic entomology: the utility of arthropods in legal investigations. CRC Press, Boca Raton, p 52

    Google Scholar 

  • Capelle KJ (1971) Myiasis. In Parasitic diseases of wild mammals. Iowa State University Press, Ames, Iowa. Pp: 279-305

  • Catts EP, Goff ML (1992) Forensic entomology in criminal investigations. Annu Rev Entomol 37:253–272

    CAS  Article  PubMed  Google Scholar 

  • Delir S, Handjani F, Emad M, Ardehali S (1999) Vulvar myiasis due to Wohlfahrtia magnifica. Clin Exp Dermatol 24:279–280

    CAS  Article  PubMed  Google Scholar 

  • Demirel Kaya F, Orkun O, Cakmak A, Inkaya AC, Erguven S (2014) Cutanous myiasis caused by Sarcophaga spp. larvae in a diabetic patient. Mikrobiyol Bul 48:356–361

    Article  PubMed  Google Scholar 

  • Diaz JH (2009) Myiasis and tungiasis. In: Mandell GL, Bennett JE, Dolin R (eds) Mandell, Douglas, and Bennett's principles and practice of infectious diseases, chapter 295, vol 2 Churchill, Livingstone, Elsevier, Philadelphia, PA

  • Dokur M, Eroglu F, Ipek DN, Ulutasdemir N (2015) Two different myiasis cases in southeast of Turkey: ophthalmomyiasis and cutaneous myiasis. Parasitol Res. doi:10.1007/s00436-015-4455-6

    PubMed  Google Scholar 

  • El-Tantawy NL (2015) Helminthes and insects: maladies or therapies. Parasitol Res 114:359–377

    Article  PubMed  Google Scholar 

  • Francesconi F, Lupi O (2012) Myiasis. Clin Microbiol Rev 25:79–105

    Article  PubMed Central  PubMed  Google Scholar 

  • Graffi S, Peretz A, Wilamowski A, Schnur H, Akad F, Naftali M (2013) External ophthalmomyiasis caused by a rare infesting larva, Sarcophaga argyrostoma. Case Rep Ophthalmol Med 2013:850865

    PubMed Central  PubMed  Google Scholar 

  • Hakeem MJ, Bhattacharyya DN (2009) Exotic human myiasis. Travel Med Infect Dis 7:198–202

    CAS  Article  PubMed  Google Scholar 

  • Hall MJW, Smith KGV (1993) Diptera causing myiasis in man. In: Lane RP, Crosskey RW (eds) Medical insects and arachnids. Chapman and Hall, London, pp 429–469

    Chapter  Google Scholar 

  • Hall RD, Anderson PC, Clark DP (1986) A case of human myiasis caused by P. regina (Diptera: Calliphoridae) in Missouri, USA. J Med Entomol 23:578–579

    CAS  Article  PubMed  Google Scholar 

  • Hays A (2007) History of medicine part 1: maggot therapy. Tropical dermatology. Elsevier, Philadelphia, pp 590–591

    Google Scholar 

  • Hope FW (1840) On insects and their larvae occasionally found in the human body. Trans R Soc Entomol (Lond) 2:256–271

    Google Scholar 

  • Huntington TE, Voigt DW, Higley LG (2008) Not the usual suspects: human wound myiasis by phorids. J Med Entomol 45:157–159

    CAS  Article  PubMed  Google Scholar 

  • Introna F, Campobasso CP, Fazio AD (1997) Three case studies in forensic entomology from southern Italy. J Forensic Sci 43:210–214

    Google Scholar 

  • John D, Petri W (2006) Markell and Voge’s medical parasitology, 9th edn. Elsevier, St. Louis, p 329

    Google Scholar 

  • Khalifa RMA, Mowafy NME (1997) Light and scanning electron microscopical identification of sarcophagid larva causing intestinal myiasis. Egypt J Med Sci 18:235–243

    Google Scholar 

  • Kim JS, Kim JW, Lee HJ, Lee IY, Oh SA, Seo M (2011) Ophthalmomyiasis caused by a Phormia sp. (Diptera: Calliphoridae) larva in an enucleated patient. Korean J Parasitol 49:173–178

    Article  PubMed Central  PubMed  Google Scholar 

  • Kingscote AA (1935) Myiasis in man and animals due to infection with the larvae of Wohlfahrtia vigil (Walker). Rep Ontario Vet Coll 29:5–69

    Google Scholar 

  • Kokcam I, Saki CE (2005) A case of cutaneous myiasis caused by Wohlfahrtia magnifica. J Dermatol 32:459–463

    Article  PubMed  Google Scholar 

  • Lucchina L, Wilson M, Drake L (1997) Dermatology and the recently returned traveler: infectious diseases with dermatologic manifestations. Int J Dermatol 36:167–181

    CAS  Article  PubMed  Google Scholar 

  • Madubunyi LC (1986) Laboratory life history parameters of the red-tailed flesh fly, Sarcophaga haemorrhoidalis (Fallén) (Diptera: Sarcophagidae). Insect Sci Appl 7:617–621

    Google Scholar 

  • Maleki-Ravasan N, Oshaghi MA, Hajikhani S, Saeidi Z, Akhavan AA, Gerami-Shoar M, Shirazi MH, Yakhchali B, Rassi Y, Afshar D (2014) Aerobic microbial community of insectary population of Phlebotomus papatasi. J Arthropod-Borne Dis 8:69–81

    PubMed Central  PubMed  Google Scholar 

  • Mandell G, Bennet J, Dolin R (2004) Myiasis and tungiasis. In: Principles and practice of infectious diseases. 6th edn. Chapter 293: pp: 3307–3317

  • Marquez AT, Mattos MD, Nascimento SB (2007) Myiasis associated with some socioeconomic factors in five urban areas of the State of Rio de Janeiro. Rev Soc Bras Med Trop 40:175–180

    Article  PubMed  Google Scholar 

  • Mathison BA, Pritt BS (2014) Laboratory identification of arthropod ectoparasites. Clin Microbiol Rev 27:48–67

    Article  PubMed Central  PubMed  Google Scholar 

  • McGraw TA, Turiansky GW (2008) Cutaneous myiasis. J Am Acad Dermatol 58:907–726

    Article  PubMed  Google Scholar 

  • Miller KB, Hribar LJ, Sanders LJ (1990) Human myiasis caused by P. regina in Pennsylvania. J Am Podiatr Med Assoc 80:600–602

    CAS  Article  PubMed  Google Scholar 

  • Namazi MR, Fallahzadeh MK (2009) Wound myiasis in a patient with squamous cell carcinoma. Sci World J 9:1192–1193

    Article  Google Scholar 

  • Nascimento EMF, Oliveira JB, Paes MJ, Lobo AP, Silva ALA, Júnior ERS, Leal JLF, Moya Borja GE (2005) Miíases humanas por Cochliomyia hominivorax (Coquerel, 1858) (Diptera, Calliphoridae) em hospitais públicos na cidade do Recife, Pernambuco, Brasil. Entomol y Vectores 12:37–51

    Article  Google Scholar 

  • Nigam Y, Bexfield A, Thomas S, Ratcliffe NA (2006) Maggot therapy: the science and implication for CAM part I—history and bacterial resistance. Evid Based Complement Alternat Med 3:223–227

    Article  PubMed Central  PubMed  Google Scholar 

  • Nishida K (1984) Experimental studies on the estimation of postmortem intervals by means of fly larvae infesting human cadavers. Jpn J Legal Med 38:24–41

    CAS  Google Scholar 

  • Norris KR (1989) Myiasis in human. Med J Aust 150:235–237

    CAS  PubMed  Google Scholar 

  • Pohjoismäki JLO, Karhunen PJ, Goebeler S, Saukko P, Sääksjärvi IE (2010) Indoors forensic entomology: colonization of human remains in closed environments by specific species of sarcosaprophagous flies. Forensic Sci Int 199:38–42

    Article  PubMed  Google Scholar 

  • Seaquist ER, Henry TR, Cheong E, Theologides A (1983) P. regina myiasis in a malignant wound. Minn Med 66:409–410

    CAS  PubMed  Google Scholar 

  • Sesterhenn AM, Pfützner W, Braulke DM, Wiegand S, Werner JA, Taubert A (2009) Cutaneous manifestation of myiasis in malignant wounds of the head and neck. Eur J Dermatol 19:64–68

    PubMed  Google Scholar 

  • Sherman RA (2004) Wound myiasis in urban and suburban United States. Arch Intern Med 160:2004–2014

    Article  Google Scholar 

  • Sherman RA (2014) Mechanisms of maggot-induced wound healing: what do we know, and where do we go from here? Evid Based Complement Alternat Med 2014:592419

    Article  PubMed Central  PubMed  Google Scholar 

  • Shi E, Shofler D (2014) Maggot debridement therapy: a systematic review. Br J Community Nurs 12:S6–S13

    Article  Google Scholar 

  • Singh TS, Rana D (1989) Urogenital myiasis caused by Megaselia scalaris (Diptera: Phoridae): case report. J Med Entomol 26:228–229

    CAS  Article  PubMed  Google Scholar 

  • Stojanovich CJ, Pratt HD, Bennington EE (1962) Fly larvae: key to some species of public health importance. U.S. Dep. Hlth., Ed., and Well., Pub. Hlth. Serv. CDC, Training Branch, Atlanta, GA, USA

  • Szpila K, Pape T, Rusknek A (2008) Morphology of the first instar of Calliphora vicina, P. regina and Lucilia illustris (Diptera, Calliphoridae). Med Vet Entomol 22:16–25

    CAS  Article  PubMed  Google Scholar 

  • Thyssen PJ, Nassu MP, Costella AM, Costella ML (2012) Record of oral myiasis by Cochliomyia hominivorax (Diptera: Calliphoridae): case evidencing negligence in the treatment of incapable. Parasitol Res 111:957–959

    Article  PubMed  Google Scholar 

  • Triplehorn C, Johnson N, Borror and Delongs (2005) Introduction to the study of insects. Brooks/Cole, 7th Ed. Pp.672 & 729–730

  • Verettas DA, Chatzipapas CN, Drosos GI, Xarchas KC, Staikos C, Chloropoulou P, Kazakos KI, Ververidis A (2008) Maggot infestation (myiasis) of external fixation pin sites in diabetic patients. Trans R Soc Trop Med Hyg 102:950–952

    Article  PubMed  Google Scholar 

  • Watson L, Dallwitz MJ (2003) Onwards. British insects: the families of Diptera. Version: 28th August 2009. http://delta-intkey.com

  • Zaglool DA, Tayeb K, Khodari YA, Farooq MU (2013) First case report of human myiasis with Sarcophaga species in Makkah city in the wound of a diabetic patient. J Nat Sci Biol Med 4:225–228

    Article  PubMed Central  PubMed  Google Scholar 

  • Zumpt F (1963) The problem of intestinal myiasis in humans. S Afr Med J 37:305–307

    CAS  PubMed  Google Scholar 

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Conflict of interest

The authors declare that they have no conflict of interest.

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Affiliations

  1. Department of Parasitology, Faculty of Medicine, Minia University, Minia, 61519, Egypt

    Ekhlas H. Abdel-Hafeez, Rabie M. Mohamed & Usama S. Belal

  2. Department of Surgery, Faculty of Medicine, Minia University, Minia, 61519, Egypt

    Ahmed M. Atiya

  3. Department of Infection and Host Defense, Graduate School of Medicine, Shinshu University, 3-1-1 Asahi, Matsumoto, 390-8621, Japan

    Masaya Takamoto & Fumie Aosai

Authors
  1. Ekhlas H. Abdel-Hafeez
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  2. Rabie M. Mohamed
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  3. Usama S. Belal
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  4. Ahmed M. Atiya
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  5. Masaya Takamoto
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  6. Fumie Aosai
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Correspondence to Rabie M. Mohamed.

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Abdel-Hafeez, E.H., Mohamed, R.M., Belal, U.S. et al. Human wound myiasis caused by Phormia regina and Sarcophaga haemorrhoidalis in Minia Governorate, Egypt. Parasitol Res 114, 3703–3709 (2015). https://doi.org/10.1007/s00436-015-4599-4

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  • DOI: https://doi.org/10.1007/s00436-015-4599-4

Keywords

  • Wound myiasis
  • Sarcophaga haemorrhoidalis
  • Phormia regina
  • Minia city
  • Egypt