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Therapeutic efficacy of Broadline® against notoedric mange in cats

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Abstract

The efficacy of a novel topical combination of fipronil 8.3 % w/v, (S)-methoprene 10 % w/v, eprinomectin 0.4 % w/v, and praziquantel 8.3 % w/v (Broadline®, Merial) was evaluated in 18 cats naturally infested by Notoedres cati in a controlled, blinded clinical efficacy study. Cats were blocked on pretreatment bodyweight and randomly allocated to two groups of nine cats each. One group served as control (untreated) and one group was treated once topically with Broadline® according to the label instructions. Skin scrapings (three scrapings per animal per occasion) were collected prior to treatment and every other week for 8 weeks thereafter and examined for live N. cati mites. In addition, lesions were evaluated at each sampling to monitor the clinical recovery. Based on live mite counts, efficacy against N. cati of a single topical administration with Broadline® was >99 %, and all treated cats recovered from clinical signs of notoedric mange. No treatment-related adverse events were observed.

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Acknowledgments

The authors gratefully acknowledge the technical assistance of Heike Ryl.

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This document is provided for scientific purposes only. Any reference to a brand or trademark herein is for informational purposes only and is not intended for a commercial purpose or to dilute the rights of the respective owner(s) of the brand(s) or trademark(s).

Conflict of interest

The work reported herein was funded by Merial Limited, GA, USA. All authors are current employees or collaborators of Merial.

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Authors and Affiliations

  1. Merial GmbH, Kathrinenhof Research Center, 83101, Rohrdorf, Germany

    Martin Knaus & Martin Visser

  2. Kapriol Bt., 8330, Sümeg, Hungary

    Balázs Capári

Authors
  1. Martin Knaus
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  2. Balázs Capári
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  3. Martin Visser
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Correspondence to Martin Knaus.

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® Broadline is a trademark of Merial. All other marks are the property of their respective owners.

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Knaus, M., Capári, B. & Visser, M. Therapeutic efficacy of Broadline® against notoedric mange in cats. Parasitol Res 113, 4303–4306 (2014). https://doi.org/10.1007/s00436-014-4126-z

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  • DOI: https://doi.org/10.1007/s00436-014-4126-z

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