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Addition of a combination of onion (Allium cepa) and coconut (Cocos nucifera) to food of sheep stops gastrointestinal helminthic infections

Parasitology Research volume 108, pages 1041–1046 (2011)Cite this article

Abstract

Sheep with gastrointestinal nematodes and cestodes were fed on three farms with a combination of specially prepared extracts of onion (Allium cepa) and coconut (Cocos nucifera) for 8 days containing each 60 g coconut and onion extract, combined with milk powder and/or polyethylene glycol (PEG) propylencarbonate (PC). In all cases, the worm stages disappeared from the feces and were also not found 9 and 20 days after the end of the feeding with this plant combination. Since all treated animals increased their body weight considerably (when compared to untreated animals), worm reduction was apparently as effective as it was shown in previous laboratory trials with rats and mice (Klimpel et al., Parasitol Res, in press, 2010; Abdel-Ghaffar et al., Parasitol Res, in press, 2010; in this volume).

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References

  • Abdel-Ghaffar F, Semmler M, Al-Rasheid KAS, Strassen B, Fischer K, Aksu G, Klimpel S, Mehlhorn H (2010) The effects of different plant extracts on intestinal cestodes and trematodes. Parasitol Res (in press) this volume

  • Abu-El-Ess NM (2005) Effects of Nigella sativa and Allium cepa oils on Trichinella spiralis in experimentally infected rats. J Egypt Soc Parasitol 35:511–523

    Google Scholar 

  • Amorim A, Borba HR (1994) Acav anthelminthica de plantas X. Testes in-vivo com extractos brutos de Cocos nucifera. Rev Bras Farm 75:91–92

    Google Scholar 

  • Amorim A, Borba HR (1995) Acav anthelminthica de plantas XI. Influencia de extractos brutos nucifera. Rev Bras Farm 76:99–99

    Google Scholar 

  • Athanasiadou S, Eithiori J, Kyriazakis I (2007) Medical plants for helminth parasite control: facts and fictions. Animal 1:1392–1400

    Article  Google Scholar 

  • Ayaz E, Türel GA, Silmaz O (2008) Evaluation of the anthelminthic activity of garlic (Allium sativum) in mice naturally infected with Aspiculuris tetraptera. Recent Pat Antiinfect Drug Disc 3:149–152

    Article  CAS  Google Scholar 

  • Bastidas G (1969) Effects of ingested garlic on Necator americanus and Ancylostoma caninum. Am J Trop Med Hyg 18:920–923

    PubMed  CAS  Google Scholar 

  • Bäumler S (2007) Heilpflanzen. Praxis heute. Urban und Fischer, Munich

    Google Scholar 

  • Blini W, Lira CM (2005) Salvado vidas com a medicina natural. Unier, Sao Paulo, p 407

    Google Scholar 

  • Bown D (1995) Encyclopedia of herbs and their uses. Dorling Kindersley, London

    Google Scholar 

  • Burke JM, Wells IJ, Wsey P, Miller JE (2009) Garlic and papaya lack control over gastrointestinal nematodes in goats and lambs. Vet Parasitol 159:171–174

    PubMed  Article  CAS  Google Scholar 

  • Chiej R (1984) Encyclopedia of medicinal plants. MacDonald, London

  • Cosha CTC, Oliveira LMB, Camurga Vasconalos ALF et al (2009) Atividade anthelminthica de Cocos nucifera. Vet Parasitol 157:211–213

    Google Scholar 

  • Costa CTC, Bevilaqua CML, Maciel BV et al (2006) Anthelminthic activity of Azadirachta indica A. Juss against sheep gastrointestinal nematodes. Vet Parasitol 137:306–310

    PubMed  Article  CAS  Google Scholar 

  • Cragg GM, Newman DJ, Snader KM (1997) Natural products in drug discovery and development. J Nat Prod 60:52–60

    PubMed  Article  CAS  Google Scholar 

  • Duke HA, Wain KK (1981) Medicinal plants of the world: a computer index with more than 85,000 entries

  • Eckert J, Friedhoff KT, Zahner H, Deplazes P (2008) Lehrbuch der Tiermedizin, 2nd edn. Enke, Stuttgart

    Google Scholar 

  • Eguale T, Tilahun G, Debella A, Feleke A, Makonnen E (2007) Haemonchus contortus: in vitro and in vivo activity of aqueaous and hydro-alcoholic extracts of Hedera helix. Exp Parasitol 116:340–345

    PubMed  Article  CAS  Google Scholar 

  • Fajimi AK, Taiwo AA (2005) Herbal remedies in animal parasitic diseases in Nigeria: a review. African J Biotechnol 4:303–307

    Google Scholar 

  • Förster M, Klimpel S, Mehlhorn H, Sievert K, Messler S, Pfeffer K (2007) Pilot study on synanthropic flies (eg. Musca, Sarcophaga, Calliphora, Fannia, Lucilia, Stomoxys) as vectors of pathogenic microorganisms. Parasitol Res 101:243–246

    PubMed  Article  Google Scholar 

  • Giove N (1996) Traditional medicine in the treatment of enteroparasites. Rev Gastroenterol Perú 16:197–202

    Google Scholar 

  • Grundzinsky IP, Frankiewitz-Kozko A, Bany J (2001) Dialyl sulfide—a flavour component from garlic (Allium sativum) attenuates lipid peroxidation in mice infected with Trichinella spiralis. Phytomedicine 8:174–177

    Article  Google Scholar 

  • Harvey A (2000) Strategies for discovering drugs from previously unexplored natural products. Drug Discov Today 5:294–300

    PubMed  Article  Google Scholar 

  • Henkel T (1999) Drugs. Angewandte Chemie. Int Ed Engl 38:643–653

    Article  CAS  Google Scholar 

  • Hördegen P, Hertzberg H, Heilmann J, Langhans W, Maurer V (2003) The efficacy of five plant products against gastrointestinal trichostrongylids in artificially infected lambs. Vet Parasitol 117:51–60

    PubMed  Article  Google Scholar 

  • Hounzangbe-Adobe MS, Paolini V, Fouraste I, Moutairon K, Hoste H (2004) In vitro effects of four tropical plants on three life-cycle stages of the parasitic nematode Haemonchus contortus. Res Vet Sci 78:155–160

    Article  Google Scholar 

  • Hussain A, Khan MN, Igbal Z, Sajid MS (2008) An account of the botanical anthelminthics used in traditional veterinary practices in Saniwal district of Punjab, Pakistan. J Ethnopharmacol 119:185–190

    PubMed  Article  Google Scholar 

  • Igbal Z, Khahid-Nadeem Q, Khan MN, Akthar MSS, Waraich FN (2001) In vitro anthelminthic activity of Allium sativum, Zingiber officinale and Ficus religiosus. Int J Agricult Biol 3:454–457

    Google Scholar 

  • Jabbar A, Zaman MA, Igbal Z, Yassen M, Shamim A (2007) Anthelminthic activity of Chenopodium album (L) and Caesalpinia crista (L) against trichostrongylid nematodes of sheep. J Ethnopharmacol 114:86–91

    PubMed  Article  CAS  Google Scholar 

  • Klimpel S, Abdel-Ghaffar F, Al-Rasheid KAS, Aksu G, Fischer K, Mehlhorn H (2010) The effects of different plant extracts on nematodes. Parasitol Res (2010 in press) this volume

  • Leung AY (1985) Chinese medical plants. Diederichs Publisher, Munich

    Google Scholar 

  • Lorimer SD, Perry NB, Foster LM, Burgess EJ (1996) A nematode larval motility inhibition assay for screening plant extracts and natural products. J Agric Food Chem 44:2842–2845

    Article  CAS  Google Scholar 

  • MacDonald D, Van Crey K, Harrison P, Rangachari PK, Rosenfeld J, Warren C, Sorger G (2004) Acaridolless infusion Chenopodium ambrosicoides contain a nematocide that is not toxic to mammalian smooth muscle. J Ethnopharmacol 92:215–221

    PubMed  Article  CAS  Google Scholar 

  • Mehlhorn H (2008) Encyclopedia of Parasitology, 3rd edn. Springer, New York

    Book  Google Scholar 

  • Mehlhorn H, Düwel D, Raether W (1993) Diagnose und Therapie der Parasitosen der Haus-, Heim-und Nutztiere. G. Fischer, Stuttgart, 2nd edition

  • Molan AL, Waghorn GC, Min BR, McNabb WC (2000) The effects of condensed tannins from seven herbalges on Trichostrongylus colubriformis larval migration in vitro. Folia Parasitol 47:39–44

    PubMed  CAS  Google Scholar 

  • Oliveira LMB, Bevilagna CML, Cosha CTC et al (2009) Anthelminthic activity of Cocos nucifera L. against sheep gastrointestinal nematodes. Vet Parasitol 159:55–59

    PubMed  Article  CAS  Google Scholar 

  • Rates SMK (2001) Plants as source of drugs. Toxicon 39:603–613

    PubMed  Article  CAS  Google Scholar 

  • Roepke DA (1996) Traditional and reapplied veterinary medicine in East Africa. In: McCokle et al (eds) Ethnoveterinary Research and Development. Intermediate Technol Publ, London

    Google Scholar 

  • Rommel M, Eckert J, Kutzer E, Boch J, Supperer R (2006) Veterinärmedizinische Parasitologie, 5th edn. Blackwell, Berlin

    Google Scholar 

  • Rotscheidt W (2008) Kann man Schafe indirekt entwurmen? Schafzucht-Tiergesundheit 17:36–37

    Google Scholar 

  • Rybaltovsky OV (1966) On the discovery of curcurbitin—a component of pumpkin seed with anthelminthic action. Med Parazitol (Mosk) 57:299–304

    Google Scholar 

  • Schönfelder A, Schönfelder P (2001) Heilpflanzenführer. Franckh-Kosmos, Stuttgart

    Google Scholar 

  • Semmler M, Abdel-Ghaffar F, Al-Rasheid KAS, Mehlhorn H (2009) Nature helps: from research to products against blood-sucking arthropods. Parasitol Res 105:1483–1487

    PubMed  Article  Google Scholar 

  • Sen HG, Joshi BS, Parthasarathy P, Kamat VN (1974) Anthelminthic efficacy of diospyrol and its derivates. Arzneimittelforschung 24:2000–2003

    PubMed  CAS  Google Scholar 

  • Stepek G, Behnke JM, Buttle DJ, Duce IR (2004) Natural plant cysteine proteinases as anthelminthics. Trends Parasitol 20:322–327

    PubMed  Article  CAS  Google Scholar 

  • Tagboto S, Townson S (2001) Antiparasitic properties of medicinal plants and other naturally occuring products. Adv Parasitol 50:200–295

    Google Scholar 

Download references

Acknowledgments

We are grateful for the support of the Center of Excellence of the College of Science at the King Saud University at Riyadh, Saudi Arabia. Furthermore, we thank Susanne Walter and Tim Mehlhorn for their cooperation in search for literature and preparation of the final manuscript.

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Authors and Affiliations

  1. Department of Zoology and Parasitology, Heinrich Heine University Düsseldorf, 40225, Düsseldorf, Germany

    Heinz Mehlhorn

  2. Department of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia

    Saleh Al-Quraishy & Khaled A. S. Al-Rasheid

  3. Veterinary cabinet, 40878, Ratingen, Germany

    Antje Jatzlau

  4. Department of Zoology, Cairo University, Giza, Egypt

    Fathy Abdel-Ghaffar

Authors
  1. Heinz Mehlhorn
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  2. Saleh Al-Quraishy
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  3. Khaled A. S. Al-Rasheid
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  4. Antje Jatzlau
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  5. Fathy Abdel-Ghaffar
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Correspondence to Heinz Mehlhorn.

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Mehlhorn, H., Al-Quraishy, S., Al-Rasheid, K.A.S. et al. Addition of a combination of onion (Allium cepa) and coconut (Cocos nucifera) to food of sheep stops gastrointestinal helminthic infections. Parasitol Res 108, 1041–1046 (2011). https://doi.org/10.1007/s00436-010-2169-3

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  • DOI: https://doi.org/10.1007/s00436-010-2169-3

Keywords

  • Allicin
  • Worm Burden
  • Trichuris
  • Allium Cepa
  • Livestock Animal