Skip to main content

Advertisement

Log in

The efficacy of neem seed extracts (Tre-san®, MiteStop®) on a broad spectrum of pests and parasites

  • Review
  • Published:
Parasitology Research Aims and scope Submit manuscript

Abstract

The paper summarizes the acaricidal and insecticidal effects of a patented neem seed extract when diluted 1:10 with shampoo or 1:20, 1:30, 1:33, 1:40, respectively, 1:66 with tap water. It was shown that a broad range of pests and parasites, such as house dust mites, poultry mites, harvest mites, Ixodes and Rhipicephalus ticks, cat fleas (adults, larvae), bed bugs (all stages), head lice and mallophaga, cockroaches (genera Blatta, Blattella, Gomphadorhina), raptor bugs (Triatoma), and even food-attacking beetle (Tenebrio molitor) might be controlled with this extract, which is available as Tre-san® (against house dust mites) and MiteStop® (against mites, ticks, insects of any kind) to become water diluted or as Wash Away Louse® or Picksan LouseStop® being diluted in a shampoo. Tests on skin compatibility proved that there are no skin irritations during or after use. However, some target species are less sensible (beetles, Triatoma stages, fly maggots), while the specimens of the other species cited above were successfully killed even at low concentrations of the extract.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+
from $39.99 /Month
  • Starting from 10 chapters or articles per month
  • Access and download chapters and articles from more than 300k books and 2,500 journals
  • Cancel anytime
View plans

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Explore related subjects

Discover the latest articles and news from researchers in related subjects, suggested using machine learning.

References

  • Abdel-Ghaffar F, Semmler M (2007) Efficacy of a neem seed extract shampoo on head lice of naturally infected humans in Egypt. Parasitol Res 100:329–332

    Article  PubMed  Google Scholar 

  • Abdel-Ghaffar F, Sobhy HM, Al-Quraishy S, Semmler M (2008a) Field study of an extract of neem seed (MiteStop®) against the red mite Dermanyssus gallinae naturally infecting poultry in Egypt. Parasitol Res 103:481–485

    Article  PubMed  Google Scholar 

  • Abdel-Ghaffar F, Al-Quraishy S, Sobhy H, Semmler M (2008b) Neem seed extract shampoo, Wash Away Louse® is an effective plant agent against Sarcoptes scabiei mites infecting dogs in Egypt. Parasitol Res 104:145–148

    Article  PubMed  Google Scholar 

  • Abdel-Ghaffar F, Semmler M, Al-Rasheid K, Mehlhorn H (2009) In vitro efficacy of Bye Mite® and Mite-Stop® on developmental stages of the red chicken mite Dermanyssus gallinae. Parasitol Res 105:1469–1471

    Article  PubMed  Google Scholar 

  • Abdel-Ghaffar F, Semmler M, Al-Rasheid KAS, Klimpel S, Mehlhorn H (2010) Comparative in-vitro tests on the efficacy and safety of 13 anti-head lice products. Parasitol Res 106:423–429

    Article  PubMed  Google Scholar 

  • Amer A, Mehlhorn H (2006) Repellency effect of forty-one essential oils against Aedes, Anopheles and Culex mosquitoes. Parasitol Res 99:478–490

    Article  PubMed  Google Scholar 

  • Athanasiadou S, Githori J, Kyriazakis (2007) Medical plants for helminth parasite control: facts and fiction. Animal 1:1392–1400

    Article  Google Scholar 

  • Bäumler S (2007) Heilpflanzen, Praxis heute [Medicinal plants, praxis of today]. Urban and Fischer, München, p 989

    Google Scholar 

  • Brown D (1996) Encyclopedia of herbs and their uses. Dumont Publisher, Cologne

    Google Scholar 

  • Fajimi AK, Taiwo AA (2005) Herbal remedies in animal parasitic diseases in Nigeria: a review. African J Biotechnol 4:303–307

    Google Scholar 

  • Heukelbach J, Oliveira FAS, Speare R (2006) A new shampoo based on neem (Azadirachta indica) is highly effective against head lice in vitro. Parasitol Res 99:353–356

    Article  PubMed  Google Scholar 

  • Kim SI, Na YE, Yi JH, Kim BS, Ahn YJ (2007) Contact and fumigant toxicity of oriental medical plant extracts against Dermanyssus gallinae (Acari: Dermanyssidae). Vet Parasitol 145:377–382

    Article  PubMed  Google Scholar 

  • Leung AY (1985) Chinese medicinal plants. Diederichs Publisher, Munich

    Google Scholar 

  • Locher N, Abdel-Ghaffar F, Al-Rasheid KAS, Mehlhorn H (2010) TEM investigations in MiteStop®-treated chicken mites. Parasitol Res (in press)

  • Lundh J, Wiktelius D, Chirico J (2005) Azadirachtin-impregnated traps for the control of Dermanyssus gallinae. Vet Parasitol 130:337–342

    Article  CAS  PubMed  Google Scholar 

  • Mehlhorn H (2008) Encylopedia of Parasitology, 2 Vol, 3rd edn. Springer, Heidelberg

    Google Scholar 

  • Mehlhorn H (2009) Not only in summer: mallophages. Dog-Cat-Horse J 1/09:22–25

    Google Scholar 

  • Mehlhorn H, Schmahl G, Schmidt J (2005) Extract of the seeds of the plant Vitex agnus castus proven to be highly efficacious as a repellent against ticks, fleas, mosquitoes and biting flies. Parasitol Res 95:363–365

    Article  PubMed  Google Scholar 

  • Mehlhorn H, Schmahl G, Schmidt H (2006) Repellency of ticks by extracts of monk pepper seeds. Chemotherapy J 15:175–178

    Google Scholar 

  • Mehlhorn H, Abdel-Ghaffar F, Al-Rasheid K (2010) It isn’t nice to have lice—a natural neem-based shampoo stops them! Nat Medicine, South Africa (in press)

  • Michaelakis A, Papachristos P, Kimbaris A et al (2009) Citrus essential oils and four enantiomeric pinenes against Culex pipiens. Parasitol Res 105:769–774

    Article  PubMed  Google Scholar 

  • Mul M, Van Niekerk T, Chirici J et al (2009) Control methods for Dermanyssus gallinae in systems of laying hens. Results of an international seminar. World Poult Sci J 65:589–598

    Article  Google Scholar 

  • Mulla MS, Su T (1999) Activity and biological effects of neem products against arthropods of medical and veterinary importance. J Am Mosq Control Assoc 15(2):133–152

    CAS  PubMed  Google Scholar 

  • Oladimeji FA, Orafidiya OO, Ogunniy TA, Adewunmi TA (2000) Pediculocidal and scabicidal properties of Lippia multiflora essential oil. J Ethnopharmacol 72:305–311

    Article  CAS  PubMed  Google Scholar 

  • Pitterman W, Lehmacher W, Kietzmann M, Mehlhorn H (2008) Treatment against blood sucking insects without skin irritation. SOÉFW-J 134:37–43

    Google Scholar 

  • Schmutterer H (ed) (2002) The neem tree, 2nd edn., Neem Foundation Publisher, Mumbai p 893

  • Semmler M, Abdel-Ghaffar F, Al-Rasheid KAS, Mehlhorn H (2009) Nature helps: from research to products against blood sucking arthropods. Parasitol Res 105:1483–1487

    Article  PubMed  Google Scholar 

Download references

Acknowledgment

We hereby gratefully acknowledge the support of the Center of Excellency of the College of Science, King Saud University, Riyadh, Saudi Arabia. We also thank Prof. Dr. Eberhard Schein (Free University of Berlin, Germany) for his support.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Heinz Mehlhorn.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Schmahl, G., Al-Rasheid, K.A.S., Abdel-Ghaffar, F. et al. The efficacy of neem seed extracts (Tre-san®, MiteStop®) on a broad spectrum of pests and parasites. Parasitol Res 107, 261–269 (2010). https://doi.org/10.1007/s00436-010-1915-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00436-010-1915-x

Keywords