Abstract
This study aimed to determine the efficacy of emodepside 2.14 %/praziquantel 8.58 % topical solution (Profender®, Bayer) in the prevention and treatment of lactogenic Toxocara cati infections. Eight pregnant cats were orally infected with T. cati eggs during late pregnancy. Four queens were treated on day 60 post conception and four queens were left untreated. The kittens of two untreated queens were treated 28 days after birth. The two other negative control litters were left untreated. The efficacy of emodepside was determined by faecal egg counts. While faecal samples of queens and litters in the control group became positive for T. cati, egg shedding was completely prevented in all four treated queens, in their litters and in the kittens from the two litters which were treated four weeks after birth. The untreated mothers of the latter stayed also coproscopically negative, which might be explained by an oral uptake of emodepside through grooming. The treatment was well tolerated by pregnant queens as well as by four-weeks-old kittens.
To our knowledge, this is the first publication that focuses on the prevention of lactogenic transmission of T. cati.
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References
Abu-Madi MA, Pal P, Al Thani A, Lewis JW (2008) Descriptive epidemiology of intestinal helminth parasites from stray cat populations in Qatar. J Helminthol 82:59–68.
Barutzki D, Schaper R (2003) Endoparasites in dogs and cats in Germany 1999–2002. Parasitol Res 90(Suppl 3):S148–S150.
Coati N, Schnieder T, Epe C (2004) Vertical transmission of Toxocara cati Schrank 1788 (Anisakidae) in the cat. Pa rasitol Res 92:142–146.
Epe C, Coati N, Schnieder T (2004) Results of parasitological examinations of faecal samples from horses, ruminants, pigs, dogs, cats, hedgehogs and rabbits between 1998 and 2002. Dtsch Tieraerztl Wochenschr 111:243–247.
Kraemer F, Hammerstein R, Stoye M, Epe C (2006) Investigations into the prevention of prenatal and lactogenic Toxocara canis infections in puppies by application of moxidectin to the pregnant dog. J Vet Med B 53:218–223.
Labarthe N, Serrao ML, Ferreira AM, Almeida NK, Guerrero J (2004) A survey of gastrointestinal helminths in cats of the metropolitan region of Rio de Janeiro, Brazil. Vet Parasitol 123:133–139.
Lopez J, Abarca K, Paredes P, Inzunza E (2006) Intestinal parasites in dogs and cats with gastrointestinal symptoms in Santiago, Chile. Rev Med Chil 134:193–200.
Martinez-Barbabosa I, Vazquez TO, Cabello RR, Cardenas EM, Chasin OA (2003) The prevalence of Toxocara cati in domestic cats in Mexico City. Vet Parasitol 114:43–49.
Miro G, Montoya A, Jimenez S, Frisuelos C, Mateo M, Fuentes I (2004) Prevalence of antibodies to Toxoplasma gondii and intestinal parasites in stray, farm and household cats in Spain. Vet Parasitol 126:249–255.
Mohammad Z, Seyed MS, Bahador S (2007) Prevalence of Toxocara cati and other intestinal helminths in stray cats in Shiraz, Iran. Trop Biomed 24:39–43.
Nutter FB, Dubey JP, Levine JF, Breitschwerdt EB, Ford RB, Stoskopf MK (2004) Seroprevalences of antibodies against Bartonella henselae and Toxoplasma gondii and fecal shedding of Cryptosporidium spp., Giardia spp., and Toxocara cati in feral and pet domestic cats. J Am Vet Med Assoc 225:1394–1398.
Overgaauw PA (1997) Aspects of Toxocara epidemiology: human toxocarosis. Crit Rev Microbiol 23:215–231.
Palmer CS, Thompson RC, Traub RJ, Rees R, Robertson ID (2008) National study of the gastrointestinal parasites of dogs and cats in Australia. Vet Parasitol 151:181–190.
Reinemeyer CR, Charles SD, Buch J, Settje T, Altreuther G, Cruthers L, McCall JW, Young DR, Epe C (2005) Evaluation of the efficacy of emodepside plus praziquantel topical solution against ascarid infections (Toxocara cati or Toxascaris leonina) in cats. Parasitol Res 97(Suppl 1):S41–S50.
Robben SR, le Nobel WE, Dopfer D, Hendrikx WM, Boersema JH, Fransen F, Eysker ME (2004) Infections with helminths and/or protozoa in cats in animal shelters in the Netherlands. Tijdschr Diergeneeskd 129:2–6.
Rohen M (2009) Endoparasitenbefall bei Fund- und Abgabehunden und -katzen in Niedersachsen und Untersuchungen zur Anthelminthikaresistenz. Tierärztl Hochschule Hannover, Doctor thesis, in press.
Sharif M, Nasrolahei M, Ziapour SP, Gholami S, Ziaei H, Daryani A, Khalilian A (2007) Toxocara cati infections in stray cats in northern Iran. J Helminthol 81:63–66.
Swerczek TW, Nielsen SW, Helmboldt CF (1971) Transmammary passage of Toxocara cati in the cat. Am J Vet Res 32:89–92.
Wetzel R (1951) Verbesserte McMaster-Kammer zum Auszählen von Wurmeiern. Tieraerztl Umschau 6:209–210.
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Wolken, S., Schaper, R., Mencke, N. et al. Treatment and Prevention of Vertical Transmission of Toxocara cati in Cats with an Emodepside/Praziquantel Spot-on Formulation. Parasitol Res 105 (Suppl 1), 75–82 (2009). https://doi.org/10.1007/s00436-009-1498-6
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DOI: https://doi.org/10.1007/s00436-009-1498-6