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Ultrastructural localization of Ani s 1, a major allergen from the fish parasite Anisakis simplex

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Abstract.

No data about the nature or function of the first major Anisakis simplex allergen, named Ani s 1, is available. The aim of this study was to investigate the ultrastructural localization of this protein, to obtain further information about it. Ani s 1 was detected in secretory granules of the excretory gland and occasionally lining the main excretory canal. Our results suggest that Ani s 1 could be a secretory product and could have an enzymatic function related to mechanisms of infection.

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Authors and Affiliations

  1. Department of Pathology, Carlos III Hospital, Sinesio Delgado 10, 28029 Madrid, Spain, , , , ,

    F. Gómez-Aguado,  A. Picazo,  M. Corcuera,  I. Casado &  M. Alonso

  2. Department of Immunology, Carlos III Hospital, Sinesio Delgado 10, 28029 Madrid, Spain, , , , ,

    M. Caballero &  I. Moneo

  3. Bial-Aristegui Research and Development Department, Bilbao, Spain, , , , ,

    J. Asturias

Authors
  1. F. Gómez-Aguado
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  2. A. Picazo
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  3. M. Caballero
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  4. I. Moneo
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  5. J. Asturias
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  6. M. Corcuera
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  7. I. Casado
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  8. M. Alonso
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Gómez-Aguado, .F., Picazo, .A., Caballero, .M. et al. Ultrastructural localization of Ani s 1, a major allergen from the fish parasite Anisakis simplex . Parasitol Res 89, 379–380 (2003). https://doi.org/10.1007/s00436-002-0726-0

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  • DOI: https://doi.org/10.1007/s00436-002-0726-0

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