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Combined microscope and endoscopy total resection of primary pineal malignant melanoma: case report and literature review

  • Review – Clinical Oncology
  • Published:
Journal of Cancer Research and Clinical Oncology Aims and scope Submit manuscript

Abstract

Background

Primary pineal malignant melanoma (PPMM) is a rare entity of primary central nervous system melanomas, with only 26 cases reported in the literature to date.

Case presentation

We report the case of a 65-year-old male with a PPMM who has prolonged survival of more than 104 weeks after combined microsurgical and endoscopic total resection. This is the first report: combined microscope and endoscopy total resection; PPMM in China; PPMM with total resection alone.

Conclusion

Combined microscope and endoscopy total resection is beneficial to prolong the survival of patients. But the best approach to treatment needs verification from more clinical cases in future.

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Data availability

The data that support the findings of this study are available on request from the corresponding author.

Abbreviations

CSF:

Cerebrospinal fluid

CT:

Computed tomography

ES:

Endoscopic-assisted surgery

MRI:

Magnetic resonance imaging

MS:

Microsurgery

PET:

Positron emission tomography

PPMM:

Primary pineal malignant melanoma

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Acknowledgements

Jibo Zhang thanks for the scholarship awarded by the China Scholarship Council (CSC 201906270198). Jibo Zhang and Zhongwei Xiong contributed equally to this work.

Funding

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

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Author notes

  1. Jibo Zhang and Zhongwei Xiong contributed equally to this work.

Authors and Affiliations

  1. Department of Neurosurgery, Zhongnan Hospital of Wuhan University, Donghu Road 169, Wuhan, 430071, China

    Jibo Zhang, Zhongwei Xiong & Jincao Chen

  2. Department of Neurologic Surgery, Mayo Clinic, Rochester, MN, 55905, USA

    Jibo Zhang

Authors
  1. Jibo Zhang
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  2. Zhongwei Xiong
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  3. Jincao Chen
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Contributions

JZ was the lead investigator and contributed to writing the report. JC was the chief investigator and the senior author of the report. ZX assisted with setting up the project and its promotion and helped with editing of the report. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Jincao Chen.

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The patient provided consent for publication of the case.

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Zhang, J., Xiong, Z. & Chen, J. Combined microscope and endoscopy total resection of primary pineal malignant melanoma: case report and literature review. J Cancer Res Clin Oncol 146, 2589–2594 (2020). https://doi.org/10.1007/s00432-020-03328-1

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  • DOI: https://doi.org/10.1007/s00432-020-03328-1

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