Abstract
Our aim was to identify factors predictive of death in preterm infants in whom inhaled nitric oxide was administered in response to poor oxygenation (oxygenation index ≥15). Of the 23 (median gestational age 28 weeks, range 24–36) infants consecutively so treated, 15 died. Non-survival was commoner in infants with air leaks (12 of 12, P < 0.002) and/or a change in their oxygenation index of less than 30% in response to inhaled nitric oxide administration (P < 0.05).
Conclusion In preterm infants given inhaled nitric oxide because of poor oxygenation, a diagnosis of airleak and a lack of initial response are predictive of death.
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Received: 18 June 1998 / Accepted in revised form: 4 November 1998
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Dimitriou, G., Greenough, A., Kavvadia, V. et al. Outcome predictors in nitric oxide treated preterm infants. Eur J Pediatr 158, 589–591 (1999). https://doi.org/10.1007/s004310051153
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DOI: https://doi.org/10.1007/s004310051153