Abstract
Some recent publications indicate that inherited disorders can ameliorate or possibly disappear if mutations responsible for the disease revert to normal. This review tries to summarize our current knowledge about reverse mutations as this information may be of special interest for attempts at somatic gene therapy.
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Received: 14 July 1997 / Accepted: 2 March 1998
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Wahn, V., Stephan, V. & Hirschhorn, R. Reverse mutations – spontaneous amelioration or cure of inherited disorders?. Eur J Pediatr 157, 613–617 (1998). https://doi.org/10.1007/s004310050896
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DOI: https://doi.org/10.1007/s004310050896