Skip to main content

Pseudohypo-aldosteronism and cholelithiasis: coincidence or pathogenetic correlation?

Abstract

Cholelithiasis is being documented with increasing frequency in the paediatric age group. Causes of gallstone formation in infants and neonates seem to differ from those in older children and adolescents. Two infants with pseudohypo-aldosteronism and cholelithiasis are reported. Salt-wasting and dehydration in pseudohypo-aldosteronism are suggested to be the pathogenetic mechanisms leading to gallstone formation possibly beginning in fetal life. The diagnosis of pseudohypo-aldosteronism may be missed, when salt-wasting is transitional. Cholelithiasis may go undetected when asymptomatic.

ConclusionPseudohypo-aldosteronism should be con sidered in infants with cholelithiasis even without ob vious salt-wasting signs. Routine ultrasonographic screening for gallstones should be performed in pa tients with pseudohypo-aldosteronism.

This is a preview of subscription content, access via your institution.

Author information

Authors and Affiliations

Authors

Additional information

Received: 15 March 1996 / Accepted: 21 August 1996

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Akkurt, I., Kuhnle, U. & Ringenberg, C. Pseudohypo-aldosteronism and cholelithiasis: coincidence or pathogenetic correlation?. Eur J Pediatr 156, 363–366 (1997). https://doi.org/10.1007/s004310050615

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s004310050615

  • Key wordsCholelithiasis 
  •  Pseudohypo-aldosteronism 
  •   Dehydration 
  •  Salt-wasting 
  •  Infant