Changes in muscular fitness and its association with blood pressure in adolescents
The aims of this study were to examine the longitudinal association between muscular fitness (MF) and blood pressure (BP) 2 years later, and to determine whether changes in MF over a 2-year period were associated with BP at follow-up, in adolescents. The sample comprised 734 youths (349 girls) aged from 12 to 18 years. MF was assessed with the standing long jump and handgrip tests. Socioeconomic status, pubertal stage, waist circumference, resting BP, and cardiorespiratory fitness were measured according to standard procedures. Regression analyses showed a significant inverse association between MF at baseline and systolic BP (β = − 0.072; p = 0.032) and rate pressure product (β = − 0.124; p < 0.001) at follow-up, after adjustments for age, sex, height, pubertal stage, and socioeconomic status. However, when analyses were further adjusted for waist circumference and cardiorespiratory fitness, these associations did not remain significant. Adolescents with persistently high and increasing MF exhibited the lowest levels of diastolic BP (F(3, 721) = 3.814, p = 0.018) and systolic BP (F(3, 721) = 3.908, p = 0.014) when compared to those with persistent low MF after adjustment for age, sex, height, socioeconomic status, cardiorespiratory fitness, and waist circumference.
What is Known:
• Currently, there is a growing interest on the health benefits of muscular fitness.
• Cross-sectional studies have identified an association between muscular fitness and blood pressure in adolescents.
What is New:
• Changes in muscular fitness during adolescence were associated with systolic and diastolic BP over a 2-year period.
• Adolescents with persistently low muscular fitness exhibited the highest levels of diastolic and systolic BP.
KeywordsMuscular strength Blood pressure Cardiometabolic health Adolescents
The authors gratefully acknowledged the participation of all adolescents and their parents, teachers, and schools of the LabMed Study. They also acknowledge the cooperation of volunteer’s subjects and the Research Centre in Physical Activity, Health and Leisure (University of Porto) for the sponsoring of the LabMed Study.
This study was supported by FCT grant BD88984/2012. The first author was given Doctoral scholarship from Brazilian government by CAPES (Coordination of Improvement of Higher Education Personnel) (Proc: 9588-13-2). The Research Centre on Physical Activity Health and Leisure (CIAFEL) is supported by UID/DTP/00617/2013 (FCT). Rute Santos has a Discovery Early Career Research Award from the Australian Research Council (DE150101921).
Drs. César Agostinis-Sobrinho and Rute Santos designed and carried out the initial analyses, drafted the initial manuscript and participated in data collection; Dr. Jonatan Ruiz participated in the study design, interpretation of data and revised the manuscript; Drs. Jorge Mota, Carla Moreira, and Luis Lopes participated in the study design and data collection, reviewed and data interpretation; Drs. Robinson Ramirez-Vélez and Antonio Garcia-Hermozo participated in analyzed the data and reviewed the manuscript; All authors approved the final manuscript as submitted.
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
Informed consent was obtained from all individual participants included in this study.
- 1.Agostinis-Sobrinho C, Santos R, Moreira C, Abreu S, Lopes L, Oliveira-Santos J, Rosário R, Póvoas S, Mota J (2016) Association between serum adiponectin levels and muscular fitness in Portuguese adolescents: LabMed Physical Activity Study. Nutr Metab Cardiovasc Dis 26(6):517–524. https://doi.org/10.1016/j.numecd.2016.02.011 CrossRefPubMedGoogle Scholar
- 2.Agostinis-Sobrinho CA, Moreira C, Abreu S, Lopes L, Sardinha LB, Oliveira-Santos J, Oliveira A, Mota J, Santos R (2017) Muscular fitness and metabolic and inflammatory biomarkers in adolescents: results from LabMed Physical Activity Study. Scand J Med Sci Sports 27(12):1873–1880. https://doi.org/10.1111/sms.12805 CrossRefPubMedGoogle Scholar
- 4.Agostinis-Sobrinho C, Abreu S, Moreira C, Lopes L, García-Hermoso A, Ramírez-Vélez R, Correa-Bautista JE, Mota J, Santos R (2017) Muscular fitness, adherence to the Southern European Atlantic Diet and cardiometabolic risk factors in adolescents. Nutr Metab Cardiovasc Dis 27(8):695–702. https://doi.org/10.1016/j.numecd.2017.04.008 CrossRefPubMedGoogle Scholar
- 6.Agostinis-Sobrinho C, Brand C, Moreira C, Lopes L, Oliveira-santos J, Silva P, Reis Gaya A, Gaya A, Mota J, Santos R, Abreu S (2018) Muscular fitness, Southern European Atlantic Diet and inflammation in adolescents. Azorean Physical Activity and Health Study II. Eur J Sports Sci 18(1):104–111. https://doi.org/10.1080/17461391.2017.1394368 CrossRefGoogle Scholar
- 7.Artero EG, Ruiz JR, Ortega FB, España-Romero V, Vicente-Rodríguez G, Molnar D, Gottrand F, González-Gross M, Breidenassel C, Moreno LA, Gutiérrez A, on behalf of the HELENA Study Group (2011) Muscular and cardiorespiratory fitness are independently associated with metabolic risk in adolescents: the HELENA study. Pediatr Diabetes 12:704–712. https://doi.org/10.1111/j.1399-5448.2011.00769.x CrossRefPubMedGoogle Scholar
- 9.Ascenso A, Palmeira A, Pedro LM, Martins S, Fonseca H (2016) Physical activity and cardiorespiratory fitness, but not sedentary behavior, are associated with carotid intima-media thickness in obese adolescents. Eur J Pediatr 175(3):391–398. https://doi.org/10.1007/s00431-015-2654-x CrossRefPubMedGoogle Scholar
- 10.Chen X, Wang Y, Chen X, YW CX, Wang Y (2008) Tracking of blood pressure from childhood to adulthood: a systematic review and meta-regression analysis. Circulation 117(25):3171–3180. https://doi.org/10.1161/CIRCULATIONAHA.107.730366. CrossRefPubMedPubMedCentralGoogle Scholar
- 11.Cohen DD, López-Jaramillo P, Santos F, Castro-Piñero J, Sandercock G. Muscle strength is associated with lower diastolic blood pressure in schoolchildren. Prev Med (Baltim). 2016;95:1–6. doi: https://doi.org/10.1016/j.ypmed.2016.11.006.
- 13.Currie C, Molcho M, Boyce W, Holstein B, Torsheim T, Richter M (2008) Researching health inequalities in adolescents: the development of the Health Behaviour in School-Aged Children (HBSC) Family Affluence Scale. Soc Sci Med 66:1429–1436. https://doi.org/10.1016/j.socscimed.2007.11.024 CrossRefPubMedGoogle Scholar
- 14.Faigenbaum AD, MacDonald JP. Dynapenia: it’s not just for grown-ups anymore. Acta Paediatr Int J Paediatr 2017;106(5):696–697. doi: https://doi.org/10.1111/apa.13797.
- 25.Lin CY, Chen PC, Kuo HK, Lin LY, Lin JW, Hwang JJ (2010) Effects of obesity, physical activity, and cardiorespiratory fitness on blood pressure, inflammation, and insulin resistance in the National Health and Nutrition Survey 1999–2002. Nutr Metab Cardiovasc Dis 20(10):713–719CrossRefPubMedGoogle Scholar
- 36.Ruiz JR, Cavero-Redondo I, Ortega FB, Welk GJ, Andersen LB, Martinez-Vizcaino V (2016) Cardiorespiratory fitness cut points to avoid cardiovascular disease risk in children and adolescents; what level of fitness should raise a red flag? A systematic review and meta-analysis. Br J Sports Med 50:1451–1458. https://doi.org/10.1136/bjsports-2015-095903 CrossRefGoogle Scholar
- 37.Seron BB, Goessler KF, Modesto EL, Almeida EW, Greguol M (2015) Blood pressure and hemodynamic adaptations after a training program in young individuals with Down syndrome. Arq Bras Cardiol:487–491. https://doi.org/10.5935/abc.20150033
- 42.WHO | A global brief on hypertension. WHO. 2013. http://www.who.int/cardiovascular_diseases/publications/global_brief_hypertension/en/#.Wthx3TeEHMI.mendeley. Accessed April 19, 2018