Acne vulgaris is associated with intensive pubertal development and altitude of residence—a cross-sectional population-based study on 6,200 boys
- 208 Downloads
Acne vulgaris is a chronic inflammatory disease with a complex pathogenesis that affects predominantly adolescents. The aim of the study was to investigate the interrelations between the presence of acne and several variables associated with somatic growth, pubertal maturation, and environmental conditions (altitude and regions of residence). A population sample of 6,200 clinically healthy boys (0–19 years) was examined and the presence of acne was determined. Height, weight, testicular volumes, penile length and circumference, as well as pubic hair were also measured. The prevalence of moderate and severe acne in the whole group was 7.74 %, while in the age group 12–19 years, it was 19.31 %. Twelve–15-year-old boys with acne were taller and heavier than the ones without. They also had increased penile length and circumference as well as larger testicular volumes. Somatometric and pubertal characteristics of 17–19-year-old boys with and without acne were similar. The prevalence of the disease did not differ between the rural and urban inhabitants. However, the acne frequency decreased with the increasing of the altitude where the boys lived. Conclusions: Our results showed that the development of acne vulgaris in male adolescents was associated with an intensive growth and pubertal maturation, while obesity per se did not play an important role. Of particular interest was the association between the prevalence of acne and the altitude of residence.
KeywordsAcne Male puberty Growth Obesity Altitude Pilosebaceous unit
- 7.Cordain L, Lindeberg S, Hurtado M, Hill K, Eaton SB, Brand-Miller J (2002) Acne vulgaris: a disease of Western civilization. Arch Dermatol 138:1584–1590Google Scholar
- 9.Di Landro A, Cazzaniga S, Parazzini F, Ingordo V, Cusano F, Atzori L, Cutrì FT, Musumeci ML, Zinetti C, Pezzarossa E, Bettoli V, Caproni M, Lo Scocco G, Bonci A, Bencini P, Naldi L, GISED Acne Study Group (2012) Family history, body mass index, selected dietary factors, menstrual history, and risk of moderate to severe acne in adolescents and young adults. J Am Acad Dermatol 67:1129–1135Google Scholar
- 16.Kilkenny M, Merlin K, Plunkett A, Marks R (1998) The prevalence of common skin conditions in Australian school students: 3. Acne vulgaris. Br J Dermatol 139:840–845Google Scholar
- 25.Shen Y, Wang T, Zhou C, Wang X, Ding X, Tian S, Liu Y, Peng G, Xue S, Zhou J, Wang R, Meng X, Pei G, Bai Y, Liu Q, Li H, Zhang J (2012) Prevalence of acne vulgaris in Chinese adolescents and adults: a community-based study of 17345 subjects in six cities. Acta Derm Venereol 92:40–44PubMedCrossRefGoogle Scholar