Skip to main content

Advertisement

Log in

Acquired nonscarring diffuse hair loss in a 3-year-old girl

  • Your Diagnosis
  • Published:
European Journal of Pediatrics Aims and scope Submit manuscript

Abstract

A 3-year-old girl showed fine, sparse, and brittle scalp hair without signs of cicatricial cutaneous alterations. Dermoscopy as well as scanning electron microscopy revealed elliptical nodes as well as constricted regions along the hair shaft.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Gebhardt M, Fischer T, Claussen U et al (1999) Monilethrix—improvement by hormonal influences? Pediatr Dermatol 16:297–300

    Article  CAS  PubMed  Google Scholar 

  2. Gummer CL, Dawber RPR, Swift JA (1981) Monilethrix: an electron-histochemical study. Br J Dermatol 105:529–541

    Article  CAS  PubMed  Google Scholar 

  3. Horev L, Djabali K, Metzker A et al (2000) Monilethrix: mutational hotspot in the helix termination motif of the human hair basic keratin 6. Hum Hered 50:325–330

    Article  CAS  PubMed  Google Scholar 

  4. Korge BP, Hamm H, Jury CS et al (1999) Identification of novel mutations in basic hair keratins hHb1 and hHb6 in monilethrix: implications for protein structure and clinical phenotype. J Invest Dermatol 113:607–612

    Article  CAS  PubMed  Google Scholar 

  5. Landau M, Brenner S, Metzker A (2002) Medical pearl: an easy way to diagnose neonatal monilethrix. J Am Acad Dermatol 46:111–112

    Article  PubMed  Google Scholar 

  6. Lewis-Jones S (2010) Paediatric dermatology. Oxford University Press, Oxford, pp 216–217

    Google Scholar 

  7. Liu C-I, Hsu C-H (2008) Rapid diagnosis of monilethrix using dermoscopy. Br J Dermatol 159:741–743

    PubMed  Google Scholar 

  8. Meyvisch K, Song M, Dourov N (1992) Review and new case reports on scanning electron microscopy of pili annulati, monilethrix and trichothiodystrophy. Scan Micro 6:537–541

    CAS  Google Scholar 

  9. Möhrenschlager M, Seidl HP, Ring J et al (2005) Pediatric tinea capitis: recognition and management. Am J Clin Dermatol 6:203–213

    Article  PubMed  Google Scholar 

  10. Paller AS, Mancini AJ (2006) Hurwitz clinical pediatric dermatology, 3rd edn. Elsevier, Philadelphia, pp 147–148

    Google Scholar 

  11. van Steensel MA, Steijlen PM, Bladergroen RS et al (2005) A missense mutation in the type II hair keratin hHb3 is associated with monilethrix. J Med Genet 42:e19

    Article  PubMed  Google Scholar 

  12. Winter H, Rogers MA, Langbein L et al (1997) Mutations in the hair cortex keratin hHb6 cause the inherited hair disease monilethrix. Nat Genet 16:372–374

    Article  CAS  PubMed  Google Scholar 

  13. Zitelli JA (1986) Pseudomonilethrix. An artifact. Arch Dermatol 122:688–690

    Article  CAS  PubMed  Google Scholar 

  14. Zlotogorski A, Marek D, Horev L et al (2006) An autosomal recessive form of monilethrix is caused by mutations in DSG4: clinical overlap with localized autosomal recessive hypotrichosis. J Invest Dermatol 126:1292–1296

    Article  CAS  PubMed  Google Scholar 

Download references

Conflict of interest

All authors declare that no organization sponsored this research.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Matthias Möhrenschlager.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Möhrenschlager, M., Weichenmeier, I., Lauener, R. et al. Acquired nonscarring diffuse hair loss in a 3-year-old girl. Eur J Pediatr 170, 127–128 (2011). https://doi.org/10.1007/s00431-010-1257-9

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00431-010-1257-9

Keywords

Navigation