Skip to main content
Log in

Effect of recreational physical activity on insulin levels in Mexican/Hispanic children

  • Original Paper
  • Published:
European Journal of Pediatrics Aims and scope Submit manuscript

Abstract

The effect of increased recreational physical activity in children on insulin levels has not yet been studied. We carried out a randomized controlled trial in 76 children 6–9 years old, 32 of them increased their physical activity and 30 maintained the same level. In the intervention group, after a week of baseline, recreational activity three times/week was programmed for 12 weeks. We compared insulin, homeostatic model assessment (HOMA) index, glucose, HDL-C, LDL-C, triglycerides, and body mass index in both groups. Thereafter, we compared groups of normal weight, overweight, and with obesity in the experimental group. The group of recreational activity increased their median daily steps (15,329 to 19,910) and decreased insulin (p < 0.001) and HOMA index (4.36 vs. 2.39, p < 0.001). The diminution of insulin levels was more significant in the overweight group (p < 0.007). In conclusion, in our group, children who increased physical activity during 12 weeks decrease insulin levels and insulin resistance without change in other metabolic and anthropometric variables.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Ainslie PN, Reilly T, Westerterp KR (2003) Estimating human energy expediture: a review of techniques with particular reference to dobly labelled water. Sports Med 33:683–698, doi:10.2165/00007256-200333090-00004

    Article  PubMed  Google Scholar 

  2. Al-Hazzaa MH (2007) Pedometer-determined physical activity among obese and non-obese 8- to 12-year-old Saudi schoolboys. J Physiol Anthropol 26:459–465, doi:10.2114/jpa2.26.459

    Article  PubMed  Google Scholar 

  3. Ara I, Vicente-Rodriguez G, Perez-Gomez J et al (2006) Influence of extracurricular sport activities on body composition and physical fitness in boys: a 3-year longitudinal study. Int J Obes 30:1062–1071, doi:10.1038/sj.ijo.0803303

    Article  CAS  Google Scholar 

  4. Aradillas-Garcia C, Malacara JM, Garay-Sevilla ME et al (2007) Prediabetes in rural and urban children in 3 states in Mexico. JCMS 2:35–39

    PubMed  CAS  Google Scholar 

  5. Atabek ME, Pirgon O (2007) Assessment of insulin sensitivity from measurements in fasting state and during an oral glucose tolerance test in obese children. J Pediatr Endocrinol Metab 20:187–195

    PubMed  CAS  Google Scholar 

  6. Balady GJ, Berra KA, Golding LA et al (2000) ACSM’s guidelines for exercise testing and prescription. Lippincont Williams & Wilkins, Indianapolis

    Google Scholar 

  7. Bell LM, Watts K, Siafarikas A et al (2007) Exercise alone reduces insulin resistance in obese children independently of changes in body composition. J Clin Endocrinol Metab 92:4230–4235, doi:10.1210/jc.2007-0779

    Article  PubMed  CAS  Google Scholar 

  8. Brooks N, Layne JE, Gordon PL (2006) Strength training improves muscle quality and insulin sensitivity in Hispanic older adults with type 2 diabetes. Int J Med Sci 4:19–27

    PubMed  Google Scholar 

  9. Caballero AE (2007) Type 2 diabetes in the Hispanic or Latino population: challenges and opportunities. Curr Opin Endocrinol Diabetes Obes 14:151–157

    PubMed  Google Scholar 

  10. Caballero AE, Bousquet-Santos K, Robles-Osorio L et al (2008) Overweight Latino children and adolescents have marked endothelial dysfunction and subclinical vascular inflammation in association with excess body fat and insulin resistance. Diabetes Care 31:576–582, doi:10.2337/dc07-1540

    Article  PubMed  CAS  Google Scholar 

  11. Cole TJ, Bellizzi MC, Flegal KM, Dietz WH (2000) Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ 320:1240–1243, doi:10.1136/bmj.320.7244.1240

    Article  PubMed  CAS  Google Scholar 

  12. Conwell LS, Trost SG, Spence L (2008) The feasibility of a home-based moderate-intensity physical activity intervention in obese children and adolescents. Br J Sports Med. doi:10.1136/bjsm.2008.046359

  13. Council on Sports Medicine and Fitness and Council on School Health Active Healthy Living (2006) Prevention of childhood obesity through increased physical activity. Pediatrics 117:1834–1842, doi:10.1542/peds.2006-0472

    Article  Google Scholar 

  14. Chen W, Srinivasan SF, Li S et al (2005) Metabolic syndrome variables at low levels in childhood are benefically associated with adulthood cardiovascular risk. Diabetes Care 28:126–131, doi:10.2337/diacare.28.1.126

    Article  PubMed  Google Scholar 

  15. Daniels SE, Greer FR, the Committee on Nutrition (2008) Lipid screening and cardiovascular health in childhood. Pediatrics 122:198–208, doi:10.1542/peds.2008-1349

    Article  PubMed  Google Scholar 

  16. Deforche B, De Bourdeaudhuij I, Debode P et al (2003) Changes in fat mass, fat-free mass and aerobic fitness in severely obese children and adolescents following a residential treatment programme. Eur J Pediatr 162:616–622, doi:10.1007/s00431-003-1247-2

    Article  PubMed  Google Scholar 

  17. Del Río-Navarro BE, Velásquez-Monroy O, Sánchez-Castillo CP et al (2004) The high prevalence of overweight and obesity in Mexican children. Obes Res 12:215–223, doi:10.1038/oby.2004.28

    Article  PubMed  Google Scholar 

  18. Duncan GE, Perri MG, Theriaque DW et al (2003) Exercise training, without weight loss, increase insulin sensibility and postheparin plasma lipase activity in previously sedentary adults. Diabetes Care 26:557–562, doi:10.2337/diacare.26.3.557

    Article  PubMed  CAS  Google Scholar 

  19. Ferguson MA, Gutin B, Le NA et al (1999) Effects of exercise training and its cessation on components of the insulin resistance syndrome in obese children. Int J Obes Relat Metab Disord 23:889–895, doi:10.1038/sj.ijo.0800968

    Article  PubMed  CAS  Google Scholar 

  20. Hancox RJ, Milne BJ, Poulton R (2004) Association between child and adolescent television viewing and adult health: a longitudinal birth cohort study. Lancet 364:257–262, doi:10.1016/S0140-6736(04)16675-0

    Article  PubMed  Google Scholar 

  21. Holten MK, Zacho M, Gaster M et al (2004) Strength training increases insulin-mediated glucose uptake, GLUT4 content and insulin signaling in skeletal muscle in patients with type 2 diabetes. Diabetes 53:294–305, doi:10.2337/diabetes.53.2.294

    Article  PubMed  CAS  Google Scholar 

  22. Janssen I, Katzmarzyk PT, Boyce WF, Health Behaviour in School-Aged Children Obesity Working Group et al (2005) Comparison of overweight and obesity prevalence in school-aged youth from 34 countries and their relationships with physical activity and dietary patterns. Obes Rev 6:123–132, doi:10.1111/j.1467-789X.2005.00176.x

    Article  PubMed  CAS  Google Scholar 

  23. Lee S, Kuk JL, Davidson LE et al (2005) Exercise without weight loss is an effective strategy for obesity reduction in obese individuals with and without type 2 diabetes. J Appl Physiol 99:1220–1225, doi:10.1152/japplphysiol.00053.2005

    Article  PubMed  Google Scholar 

  24. Lorenzo C, Williams K, Hunt KJ, Haffne SM (2006) Trend Preval Metab Syndr Its Impact Incidence Diabetes Care 29:625–630

    Google Scholar 

  25. Matthews DR, Hosker JP, Rudenski AS (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28:412–419, doi:10.1007/BF00280883

    Article  PubMed  CAS  Google Scholar 

  26. Maud PJ, Foster C (1995) Physiological assessment of human fitness. Human Kinetics, Philadelphia, USA

    Google Scholar 

  27. Monzavi R, Dreimane D, Geffner ME et al (2006) Improvement in risk factors for metabolic syndrome and insulin resistance in overweight youth who are treated with lifestyle intervention. Pediatrics 117:e1111–e1118, doi:10.1542/peds.2005-1532

    Article  PubMed  Google Scholar 

  28. Poehlman ET, Dvorak RV, De Nino WF et al (2000) Effects of resistance training and endurance training on insulin sensitivity in nonobese, young women: a controlled randomized trail. J Clin Endocrinol Metab 85:2463–2468, doi:10.1210/jc.85.7.2463

    Article  PubMed  CAS  Google Scholar 

  29. Prangrazi PR, Beighele A, Beige T, Vack C (2003) Impact of Promoting Lifestyle Activity for Youth (PLAY) on children’s physical activity. J Sch Health 73:317–321

    Article  Google Scholar 

  30. Proctor MH, Moore LL, Gao D et al (2003) Television viewing and change in body fat from preschool to early adolescence: the Framingham Children’s Study. Int J Obes 27:827–833, doi:10.1038/sj.ijo.0802294

    Article  CAS  Google Scholar 

  31. Redman LM, Heilbronn LK, Martin CK et al (2007) Effect of calorie restriction with or without exercise on body composition and fat distribution. J Clin Endocrinol Metab 92:865–872, doi:10.1210/jc.2006-2184

    Article  PubMed  CAS  Google Scholar 

  32. Rosenberg DE, Sallis JF, Conway TL et al (2006) Active transportation to school over 2 years in relation to weight status and physical activity. Obesity (Silver Spring) 14:1771–1776, doi:10.1038/oby.2006.204

    Article  Google Scholar 

  33. Ross R, Janssen I, Dawson J et al (2004) Exercise-induced reduction in obesity and insulin resistance in women: a randomized controlled trial. Obes Res 12:789–798, doi:10.1038/oby.2004.95

    Article  PubMed  Google Scholar 

  34. Saris WH, Blair SN, van Baak MA et al (2003) How much physical activity is enough to prevent unhealthy weight gain? Outcome of the IASO 1st stock conference and consensus statement. Obes Rev 4:101–114, doi:10.1046/j.1467-789X.2003.00101.x

    Article  PubMed  CAS  Google Scholar 

  35. Shoelson SE, Lee J, Goldfine AB (2006) Inflammation and insulin resistance. J Clin Invest 116:1793–1801, doi:10.1172/JCI29069

    Article  PubMed  CAS  Google Scholar 

  36. Sothern MS, Loftin M, Suskind RM et al (1999) The health benefits of physical activity in children and adolescents: implications for chronic disease prevention. Eur J Pediatr 158:271–274, doi:10.1007/s004310051070

    Article  PubMed  CAS  Google Scholar 

  37. Sugiura H, Kajima K, Mirbod SM et al (2002) Effects of long-term moderate exercise and increase in number of daily steps on serum lipids in women: randomised controlled trial ISRCTN21921919. BMC Womens Health 2:3, doi:10.1186/1472-6874-2-3

    Article  PubMed  Google Scholar 

  38. Tapia-Ceballos L (2007) Metabolic syndrome in childhood. Ann Pediat (Barc) 66:159–166

    Article  CAS  Google Scholar 

  39. Ten S, Maclaren N (2004) Insulin resistance syndrome in children. J Clin Endocrinol Metab 89:2526–2539, doi:10.1210/jc.2004-0276

    Article  PubMed  CAS  Google Scholar 

  40. Vaidya D, Szklo M, Liu K et al (2007) Defining the metabolic syndrome construct: multi-ethnic study of atherosclerosis (MESA) cross-sectional analysis. Diabetes Care 30:2086–2090, doi:10.2337/dc07-0147

    Article  PubMed  Google Scholar 

  41. Ziviani J, Scott J, Wadley D (2004) Walking to school: Incidental physical activity in the daily occupations of Australian children. Occup Ther Int 11:1–11, doi:10.1002/oti.193

    Article  PubMed  Google Scholar 

Download references

Acknowledgment

This study was supported in part by grant number FOMIX GTO-2006-C01-31929.

Conflict of interest statement

The authors do not have financial interest with the organization that sponsored this work.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ma. Eugenia Garay-Sevilla.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Macias-Cervantes, M.H., Malacara, J.M., Garay-Sevilla, M.E. et al. Effect of recreational physical activity on insulin levels in Mexican/Hispanic children. Eur J Pediatr 168, 1195–1202 (2009). https://doi.org/10.1007/s00431-008-0907-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00431-008-0907-7

Keywords

Navigation