Skip to main content
Log in

Wernicke’s encephalopathy in a patient with nephrotic syndrome

  • Original Paper
  • Published:
European Journal of Pediatrics Aims and scope Submit manuscript

Abstract

We report on a 6-year-old boy with nephrotic syndrome (NS) who developed Wernicke’s encephalopathy (WE) concomitantly with posterior reversible encephalopathy syndrome (PRES). In this case, the recurrence of encephalopathy with different causes made his clinical picture complex, and the follow-up findings of magnetic resonance imaging (MRI) were critically useful for the adequate diagnosis and timely management of the patient. This case suggests the need to consider WE as a possible serious complication in patients with NS, and also emphasizes the usefulness of MRI in the diagnosis of WE, especially in pediatric cases with complex clinical symptoms.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Bae S-J, Lee HK, Lee J-H et al (2001) Wernicke’s encephalopathy: atypical manifestation at MR imaging. AJNR Am J Neuroradiol 22:1480–1482

    PubMed  CAS  Google Scholar 

  2. Carvajal E, Verdeguer A, Fernández J-M et al (2001) Herpesvirus-6 encephalitis complicated by Wernicke-Korsakoff syndrome in a pediatric recipient of unrelated cord blood transplantation. J Pediatr Hematol Oncol 23:626–628. doi:10.1097/00043426-200112000-00016

    Article  PubMed  CAS  Google Scholar 

  3. Coe M, Carfagnini F, Tani G et al (2001) Wernicke’s encephalopathy in a child: case report and MR findings. Pediatr Radiol 31:167–168. doi:10.1007/s002470000396

    Article  PubMed  CAS  Google Scholar 

  4. Fattal-Valevski A, Kesler A, Sela B-A et al (2005) Outbreak of life-threatening thiamine deficiency in infants in Israel caused by a defective soy-based formula. Pediatrics 115:233–238. doi:10.1542/peds.2004-1255

    Article  Google Scholar 

  5. Gropman AL, Gaillard WD, Campbell P et al (1998) Wernicke’s encephalopathy due to self starvation in a child. Lancet 351:1704–1705. doi:10.1016/S0140-6736(05)77742-4

    Article  PubMed  CAS  Google Scholar 

  6. Harter SB, Nokes SR (1995) Gadolinium-enhanced MR findings in a pediatric case of wernicke encephalopathy. AJNR Am J Neuroradiol 16:700–702

    PubMed  CAS  Google Scholar 

  7. Ming X, Wang MM, Zee D et al (1998) Wernicke’s encephalopathy in a child with prolonged vomiting. J Child Neurol 13:187–189

    Article  PubMed  CAS  Google Scholar 

  8. Oka M, Terae S, Kobayashi R et al (2001) Diffusion-weighted MR findings in a reversible case of acute Wernicke encephalopathy. Acta Neurol Scand 104:178–181. doi:10.1034/j.1600-0404.2001.00098.x

    Article  PubMed  CAS  Google Scholar 

  9. Peters TE, Parvin M, Petersen C et al (2007) A case report of Wernicke’s encephalopathy in a pediatric patient with anorexia nervosa—restricting type. J Adolesc Health 40:376–383. doi:10.1016/j.jadohealth.2006.11.140

    Article  PubMed  Google Scholar 

  10. Unlu E, Cakir B, Asil T (2006) MRI findings of Wernicke encephalopathy revisited due to hunger strike. Eur J Radiol 57:43–53. doi:10.1016/j.ejrad.2005.07.002

    Article  PubMed  Google Scholar 

  11. Vasconcelos MM, Silva KP, Vidal G et al (1999) Early diagnosis of pediatric Wernicke’s encephalopathy. Pediatr Neurol 20:289–294. doi:10.1016/S0887-8994(98)00153-2

    Article  PubMed  CAS  Google Scholar 

  12. Weidauer S, Nichtweiss M, Lanfermann H et al (2003) Wernicke encephalopathy: MR findings and clinical presentation. Eur Radiol 13:1001–1009

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Masashi Nishida.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Nishida, M., Sato, H., Kobayashi, N. et al. Wernicke’s encephalopathy in a patient with nephrotic syndrome. Eur J Pediatr 168, 731–734 (2009). https://doi.org/10.1007/s00431-008-0833-8

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00431-008-0833-8

Keywords

Navigation