European Journal of Pediatrics

, Volume 168, Issue 5, pp 625–627 | Cite as

Effectiveness of pamidronate in severe neonatal hypercalcemia caused by subcutaneous fat necrosis: a case report

  • G. Lombardi
  • R. Cabano
  • L. Bollani
  • C. Del Forno
  • M. Stronati
Short Report


Subcutaneous fat necrosis of the newborn (SCFN) is a panniculitis that develops in fatty areas during the first weeks of life after foetal distress or perinatal complications. Prognosis is generally good with complete regression, but it can be complicated by metabolic abnormalities like hypoglycemia, hypertriglyceridemia, thrombocytopenia, and also potentially life-threatening hypercalcemia. We report a case of severe hypercalcemia complicating SCFN in a newborn who was treated with hyperhydration, furosemide, prednisone, and pamidronate.


Hypercalcemia Newborn Pamidronate Subcutaneous fat necrosis Therapy 



Subcutaneous fat necrosis of the newborn


Sclerema neonatorum


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Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • G. Lombardi
    • 1
  • R. Cabano
    • 1
  • L. Bollani
    • 1
  • C. Del Forno
    • 2
  • M. Stronati
    • 1
  1. 1.Neonatal Intensive Care UnitPaviaItaly
  2. 2.Institute of DermatologyUniversity of PaviaPaviaItaly

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