Skip to main content

Advertisement

SpringerLink
Log in

Severe mycobacterial infections in two pairs of Chinese siblings with interleukin-12 receptor β1 deficiency

  • Short Report
  • Published:
European Journal of Pediatrics Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. Alcais A, Fieschi C, Abel L, Casanova L (2005) Tuberculosis in children and adults: two distinct genetic diseases. J Exp Med 202:1617–1621

    Article  PubMed  CAS  Google Scholar 

  2. Aksu G, Trpan C, Cavusoglu C, Soydan S, Altare F, Casanova J, Kutukculer N (2001) Mycobacterium fortuitum-chelonae complex infection in a child with complete interleukin-12 receptor beta 1 deficiency. Pediatr Infect Dis J 20:551–553

    PubMed  CAS  Google Scholar 

  3. Altare F, Ensser A, Breiman A, Reichenbach J, Baghdadi J, Fischer A, Emile J, Gaillard J, Meinl E, Casanova J (2001) Interleukin-12 receptor β1 deficiency in a patient with abdominal tuberculosis. J Infect Dis 184:231–236

    Article  PubMed  CAS  Google Scholar 

  4. Caragol I, Raspall M, Fieschi C, Feinberg J, Larrosa MN, Hernández M, Figueras C, Bertrán J, Casanova J, Español T (2003) Clinical tuberculosis in 2 of 3 siblings with interleukin-12 receptor β1 deficiency. Clin Infect Dis 37:302–306

    Article  PubMed  CAS  Google Scholar 

  5. Fieschi C, Dupuis Z, Catherinot E, Feinberg F, Bustamante J, Breiman A, Altare F, Baretto R, Le Deist F, Kayal S, Koch H, Richter D, Brezina M, Aksu G, Wood P, Jumaah S, Raspall M, da Silva Duarte A, Tuerlinckx D, Virelizier J, Fischer A, Enright A, Bernhöft J, Cleary AM, Vermylen C, Rodriguez-Gallego C, Davies G, Blütters-Sawatzki R, Siegrist C, Ehlayel MS, Novelli V, Haas WH, Levy J, Freihorst J, Al-Hajjar S, Nadal, Vasconcelos D, Jeppsson O, Kutukculer N, Frecerova K, Caragol I, Lammas D, Kumararatne DS, Abel L, Casanova J (2003) Low penetrance, broad resistance, and favorable outcome of interleukin 12 receptor β1 deficiency: medical and immunological implications. J Exp Med 197:527–535

    Article  PubMed  CAS  Google Scholar 

  6. Özbek N, Fieschi C, Yilmaz BT, de Beaucoudrey L, Demirhan B, Feinberg J, Bikmaz YE, Casanova J (2005) Interleukin-12 receptor β1 chain deficiency in a child with disseminated tuberculosis. Clin Infect Dis 40:e55–e58

    Article  PubMed  Google Scholar 

  7. Ozen M, Ceyhan M, Sanal O, Bayraktar M, Mesci L (2006) Recurrent Salmonella bacteremia in interleukin-12 receptor β1 deficiency. J Trop Pediatr 52:296–298

    Article  PubMed  Google Scholar 

  8. Sanal O, Turul T, de Boer T, van de Vosse E, Yalcin I, Tezcan I, Sun C, Memis L, Ottenhoff TH, Ersoy F (2006) Presentation of interleukin-12/-23 receptor β1 deficiency with various clinical symptoms of salmonella infections. J Clin Immunol 26:1–6

    Article  PubMed  CAS  Google Scholar 

  9. Tanir G, Dogu F, Tuygun N, Ikinciogullari A, Aytekin C, Aydemir C, Yuksek M, Boduroglu EC, de Beaucoudrey L, Fieschi C, Feinberg J, Casanova J, Babacan E (2006) Complete deficiency of the IL-12 receptor β1 chain: three unrelated Turkish children with unusual clinical features. Eur J Pediatr 165:215–217

    Article  Google Scholar 

  10. World Health Organization (WHO) Global Health Atlas, TB. Available via: http://www.who.int/globalatlas/predefinedReports/TB/

Download references

Author information

Authors and Affiliations

  1. Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, People’s Republic of China

    P. P. W. Lee, K. W. Chan, W. W. Tu & Y. L. Lau

  2. Chongqing Children’s Hospital, Chongqing University of Medical Sciences, Chongqing, People’s Republic of China

    L. P. Jiang

  3. Children’s Hospital of Fudan University, Shanghai, People’s Republic of China

    X. C. Wang

  4. Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, Room 117, 1/F New Clinical Building, Pokfulam, Hong Kong, Hong Kong SAR, People’s Republic of China

    Y. L. Lau

Authors
  1. P. P. W. Lee
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. L. P. Jiang
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. X. C. Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. K. W. Chan
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. W. W. Tu
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Y. L. Lau
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Y. L. Lau.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lee, P.P.W., Jiang, L.P., Wang, X.C. et al. Severe mycobacterial infections in two pairs of Chinese siblings with interleukin-12 receptor β1 deficiency. Eur J Pediatr 167, 231–232 (2008). https://doi.org/10.1007/s00431-007-0430-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00431-007-0430-2

Keywords

Search

Navigation