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Unusual clinical presentation of primary hypothyroidism in a very young infant caused by autoimmune thyroiditis: case report and update of the literature

European Journal of Pediatrics volume 166, pages 881–883 (2007)Cite this article

Abstract

Acquired primary hypothyroidism in infancy can be related to autoimmune thyroiditis and can present with unusual symptoms, such as muscle pseudohypertrophy and pituitary tumor. This condition can cause permanent deficits in psychomotor development and growth despite adequate replacement with L-thyroxine.

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References

  1. Foley TP, Abassi V, Copeland KC, Drazain MB (1994) Hypothyroidism caused by chronic Autoimmune Thyroiditis in very young infants. N Engl J Med 330:466–468

    PubMed  Article  Google Scholar 

  2. Hopper NW, Albanese A (2005) Primary Hypothyroidism in a child mimicking a pituitary macroadenoma. Horm Res 63:61–64

    PubMed  Article  CAS  Google Scholar 

  3. Kaino Y, Otoh Y, Tobuda K, Hirai H, Ito T, Kida K (2000) Acquired Hypothyroidism in a very young infant with Omen’s syndrome. J Pediatr 136:111–113

    PubMed  Article  CAS  Google Scholar 

  4. Kruse K (1984) Myopathien in Endokrinopathien. Monatsschr Kinderheilkd 132:581–586

    PubMed  CAS  Google Scholar 

  5. Lafranchi S (1992) Thyroiditis and Acquired Hypothyroidism. Pediatr Ann 21:29, 32–39

    PubMed  CAS  Google Scholar 

  6. Ostergaard GZ, Jacobsen BB (1989) Atrophic autoimmune thyroiditis in infancy. Horm Res 31:190–192

    PubMed  CAS  Article  Google Scholar 

  7. Reinken J, van Oost G (1992) Longitudinale Körperentwicklung gesunder Kinder von 0 bis 18 Jahren. Körperlänge/-höhe, Körpergewicht und Wachstumsgeschwindigkeit. Klin. Pädiatr 204:129–133

    PubMed  CAS  Article  Google Scholar 

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Affiliations

  1. Division of Paediatric Endocrinology and Diabetes, Children’s Hospital, University of Heidelberg, Im Neuenheimer Feld 153, 69120, Heidelberg, Germany

    Janna Mittnacht, Fabian Schmidt, Friedrich Ebinger & Markus Bettendorf

Authors
  1. Janna Mittnacht
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  2. Fabian Schmidt
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  3. Friedrich Ebinger
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  4. Markus Bettendorf
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Correspondence to Janna Mittnacht.

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Mittnacht, J., Schmidt, F., Ebinger, F. et al. Unusual clinical presentation of primary hypothyroidism in a very young infant caused by autoimmune thyroiditis: case report and update of the literature. Eur J Pediatr 166, 881–883 (2007). https://doi.org/10.1007/s00431-006-0323-9

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  • DOI: https://doi.org/10.1007/s00431-006-0323-9

Keywords

  • Acquired hypothyroidism
  • Autoimmune thyroiditis
  • Pituitary tumor
  • Psychomotoric development
  • Pseudohypertrophy of the muscle