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ANCA-associated diffuse alveolar hemorrhage due to benzylthiouracil

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Abstract

Benzylthiouracil has been recently observed to be associated with antineutrophil cytoplasmic antibody-positive vasculitis, resulting in crescentic glomerulonephritis. We report an 8-year-old girl treated with benzylthiouracil for Graves’s disease who developed an ANCA-positive vasculitis with pulmonary hemorrhage. She responded to corticosteroids and discontinuation of benzylthiouracil. This represents the first pediatric case of benzylthiouracil-induced diffuse alveolar hemorrhage.

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Abbreviations

ANCA:

Antineutrophil cytoplasmic antibody

DAH:

Diffuse alveolar hemorrhage

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Correspondence to Farah Thabet.

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Thabet, F., Sghiri, R., Tabarki, B. et al. ANCA-associated diffuse alveolar hemorrhage due to benzylthiouracil. Eur J Pediatr 165, 435–436 (2006). https://doi.org/10.1007/s00431-005-0053-4

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  • DOI: https://doi.org/10.1007/s00431-005-0053-4

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