European Journal of Pediatrics

, Volume 165, Issue 4, pp 273–274 | Cite as

Varicella-related complications and hospitalisations in a tertiary pediatric medical center before vaccine introduction

  • Maria TheodoridouEmail author
  • Ioanna Laina
  • Christos Hadjichristodoulou
  • Vassiliki Syriopoulou
Short Report

The aim of this study was to identify varicella complications in children and assess the hospitalisation rates in the pre-vaccination era.

The present study was conducted in Aghia Sophia Children’s Hospital, which is located in the Athens metropolitan area and serves approximately 650,000 children 0–14 years of age. The records of patients discharged with the diagnosis of varicella from January 1998 to December 2002 were reviewed, and pertinent information regarding demographic data, complications, and outcome was abstracted. Complications were categorised by the main system involved and analysed only for immunocompetent children. Annual incidence of hospitalisation rates of varicella was calculated per 100,000 children in each age group. Population figures were based on the latest census (2000) and predicted changes in the paediatric population of the aforementioned geographic area.

Five hundred and seventy-three children were hospitalised for varicella during the study period. Of...


Varicella Varicella complications Hospitalisation rate 


  1. 1.
    Galil K, Brown C, Lin F, Seward J (2002) Hospitalizations for varicella in the United States, 1988 to 1999. Pediatr Infect Dis J 21:931–935PubMedCrossRefGoogle Scholar
  2. 2.
    Law B, Mc Donald N, Halperin S, Sheifele D, Dery P, Jadavji T, Lebel M, Mills E, Morris R, Vaundry W, Gold R, Marchessault V, Duclos P (2000). The Immunization Monitoring Program Active (IMPACT) prospective five-year study of Canadian children hospitalized for chickenpox or an associated complication. Ped Infect Dis J 19:1053–1059CrossRefGoogle Scholar
  3. 3.
    Rentier B, Gershon AA (2004) European Working Group on Varicella. Consensus: varicella vaccination of healthy children-a challenge for Europe. Pediatr Infect Dis J 23:379–389PubMedCrossRefGoogle Scholar
  4. 4.
    Tseng HW, Liu CC, Wang SM, Yang YJ, Huang YS (2000) Complications of varicella in children: emphasis on skin and central nervous system disorders. J Microbiol Immunol Infect 33:248–252PubMedGoogle Scholar
  5. 5.
    Perez-Yarza EG, Arranz L, Alustiza J, Azkunaga B, Uriz J, Sarasua A, Mendiburu L, Embaranja JL, Grupo Varicela Gipuzkoa (2003) Hospital admissions for varicella complications in children aged less than 15 years old. An Pediatr (Barc) 59:229–233CrossRefGoogle Scholar
  6. 6.
    Jaeggi A, Zurbruegg RP, Aebi C (1998) Complications of varicella in a defined central European population. Arch Dis Child 79:472–479PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  • Maria Theodoridou
    • 1
    Email author
  • Ioanna Laina
    • 1
  • Christos Hadjichristodoulou
    • 2
  • Vassiliki Syriopoulou
    • 1
  1. 1.First Department of PaediatricsAghia Sophia Children’s HospitalAthensGreece
  2. 2.Department of Epidemiology, Faculty of MedicineUniversity of ThessalyLarissaGreece

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