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Borna disease virus RNA in peripheral blood mononuclear cells obtained from healthy dairy cattle

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Abstract

We examined natural infection of Borna disease virus (BDV) in 74 healthy dairy cattle in Japan. The seroprevalence determined using recombinant BDV p24 protein was 20.3%. The prevalence of BDV RNA in peripheral blood mononuclear cells (PBMCs) determined by polymerase chain reaction for p24 was 10.8%. Cell fraction of the PBMCs revealed the presence of BDV RNA in the T cell-enriched fraction. Thus, BDV infection is wide-spread even among healthy cattle.

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Authors and Affiliations

  1. Section of Serology, Institute of Immunological Science, Hokkaido University, Kita-15, Nishi-7, Kita-ku, Sapporo, 060 Japan Tel./Fax: 81-11-707-6837; e-mail: kiimm.hokudai.ac.jp, , , , , , JP

    Katsuro Hagiwara, Takaaki Nakaya, Yurie Nakamura, Sayumi Asahi, Hirokazu Takahashi & K. Ikuta

  2. Department of Animal Model, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Japan, , , , , , JP

    Chiaki Ishihara

Authors
  1. Katsuro Hagiwara
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  2. Takaaki Nakaya
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  3. Yurie Nakamura
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  4. Sayumi Asahi
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  5. Hirokazu Takahashi
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  6. Chiaki Ishihara
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  7. K. Ikuta
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Received: 12 August 1996

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Hagiwara, K., Nakaya, T., Nakamura, Y. et al. Borna disease virus RNA in peripheral blood mononuclear cells obtained from healthy dairy cattle. Med Microbiol Immunol 185, 145–151 (1996). https://doi.org/10.1007/s004300050024

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  • DOI: https://doi.org/10.1007/s004300050024

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