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Polymerase chain reaction-based detection of lymphatic filariasis

  • Developments in Filariasis Research
  • Published:
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Abstract.

PCR-based diagnostic assays are promising tools for the monitoring and evaluation of the Global Programme for Elimination of Lymphatic Filariasis. Sensitive and specific assays have been described for the detection of Wuchereria bancrofti, Brugia malayi, or Brugia timori infection in blood, sputum, and vectors. These techniques can be most cost-effective when employed for pool screening, which is important in the later stages of control programs when infection rates of humans and vectors are low, and large numbers of samples must be examined.

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Authors and Affiliations

  1. Bernhard Nocht Institute for Tropical Medicine, Bernhard-Nocht-Strasse 74, 20359 Hamburg, Germany, , , , ,

    Peter Fischer

  2. Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Accra, Ghana, , , , ,

    Daniel Boakye

  3. Kuvin Center for the Study of Infectious and Tropical Diseases, Hebrew University of Jerusalem, Israel, , , , ,

    Joseph Hamburger

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  1. Peter Fischer
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  2. Daniel Boakye
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  3. Joseph Hamburger
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Fischer, P., Boakye, D. & Hamburger, J. Polymerase chain reaction-based detection of lymphatic filariasis. Med Microbiol Immunol 192, 3–7 (2003). https://doi.org/10.1007/s00430-002-0152-z

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  • DOI: https://doi.org/10.1007/s00430-002-0152-z

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