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Role of influenza A virus hemagglutinin in neurovirulence for mammalians

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Abstract.

Influenza viruses with potential neuroinvasiveness for humans emerged in Hong Kong in 1997. Prophylactic and therapeutic strategies are urgently needed for controlling the central nervous system complications caused by influenza. Here we review recent advances toward understanding of the possible mechanisms of the neuropathogenesis of influenza virus infection, especially focusing on the role of viral hemagglutinin glycoprotein.

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Authors and Affiliations

  1. Department of Microbiology, Fukui Medical University School of Medicine, Shimoaizuki 23-3, Matsuoka-cho, Yoshida-gun, Fukui 910-1193, Japan, , , , ,

    Isamu Mori & Yoshinobu Kimura

  2. Department of Microbiology and Immunology, Aichi Medical University School of Medicine, Yazako Karimata 21, Nagakute-cho, Aichi-gun, Aichi 480-1195, Japan, , , , ,

    Takashi Yokochi

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  1. Isamu Mori
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  2. Takashi Yokochi
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  3. Yoshinobu Kimura
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Mori, I., Yokochi, T. & Kimura, Y. Role of influenza A virus hemagglutinin in neurovirulence for mammalians. Med Microbiol Immunol 191, 1–4 (2002). https://doi.org/10.1007/s00430-002-0110-9

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  • DOI: https://doi.org/10.1007/s00430-002-0110-9

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