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Optic flow selectivity in the macaque parieto-occipital sulcus

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Abstract

In humans, several neuroimaging studies have demonstrated that passive viewing of optic flow stimuli activates higher-level motion areas, like V6 and the cingulate sulcus visual area (CSv). In macaque, there are few studies on the sensitivity of V6 and CSv to egomotion compatible optic flow. The only fMRI study on this issue revealed selectivity to egomotion compatible optic flow in macaque CSv but not in V6 (Cotterau et al. Cereb Cortex 27(1):330–343, 2017, but see Fan et al. J Neurosci. 35:16303–16314, 2015). Yet, it is unknown whether monkey visual motion areas MT + and V6 display any distinctive fMRI functional profile relative to the optic flow stimulation, as it is the case for the homologous human areas (Pitzalis et al., Cereb Cortex 20(2):411–424, 2010). Here, we described the sensitivity of the monkey brain to two motion stimuli (radial rings and flow fields) originally used in humans to functionally map the motion middle temporal area MT + (Tootell et al. J Neurosci 15: 3215-3230, 1995a; Nature 375:139–141, 1995b) and the motion medial parietal area V6 (Pitzalis et al. 2010), respectively. In both animals, we found regions responding only to optic flow or radial rings stimulation, and regions responding to both stimuli. A region in the parieto-occipital sulcus (likely including V6) was one of the most highly selective area for coherently moving fields of dots, further demonstrating the power of this type of stimulation to activate V6 in both humans and monkeys. We did not find any evidence that putative macaque CSv responds to Flow Fields.

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Acknowledgements

We thank Prof. Marty Sereno for helping with the visual stimulation.

Funding

The work was supported by the University of Foro Italico, Rome, Grant to SP (CDR2.FFABR).

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Author notes

  1. Sabrina Pitzalis and Fadila Hadj-Bouziane contributed equally to this work.

Authors and Affiliations

  1. Department of Movement, Human and Health Sciences, University of Rome ‘‘Foro Italico’’, Rome, Italy

    Sabrina Pitzalis

  2. Department of Cognitive and Motor Rehabilitation and Neuroimaging, Santa Lucia Foundation (IRCCS Fondazione Santa Lucia), Rome, Italy

    Sabrina Pitzalis

  3. Integrative Multisensory Perception Action and Cognition Team (ImpAct), INSERM U1028, CNRS UMR5292, Lyon Neuroscience Research Center (CRNL), Lyon, France

    Fadila Hadj-Bouziane, Carole Guedj, Martine Meunier & Alessandro Farnè

  4. University of Lyon 1, Lyon, France

    Fadila Hadj-Bouziane, Carole Guedj, Martine Meunier & Alessandro Farnè

  5. Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy

    Giulia Dal Bò, Patrizia Fattori & Claudio Galletti

  6. Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel

    Francesca Strappini

Authors
  1. Sabrina Pitzalis
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  2. Fadila Hadj-Bouziane
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Corresponding author

Correspondence to Sabrina Pitzalis.

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Conflict of interest

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Ethical approval

The study was approved by French Animal Experimentation Ethics Committee #42 (CELYNE).

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The study was carried out in accordance with European Union Directive 2010/63/EU.

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Pitzalis, S., Hadj-Bouziane, F., Dal Bò, G. et al. Optic flow selectivity in the macaque parieto-occipital sulcus. Brain Struct Funct 226, 2911–2930 (2021). https://doi.org/10.1007/s00429-021-02293-w

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  • DOI: https://doi.org/10.1007/s00429-021-02293-w

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