The multilingual brain implements mechanisms that serve to select the appropriate language as a function of the communicative environment. Engaging these mechanisms on a regular basis appears to have consequences for brain structure and function. Studies have implicated the caudate nuclei as important nodes in polyglot language control processes, and have also shown structural differences in the caudate nuclei in bilingual compared to monolingual populations. However, the majority of published work has focused on the categorical differences between monolingual and bilingual individuals, and little is known about whether these findings extend to multilingual individuals, who have even greater language control demands. In the present paper, we present an analysis of the volume and morphology of the caudate nuclei, putamen, pallidum and thalami in 75 multilingual individuals who speak three or more languages. Volumetric analyses revealed a significant relationship between multilingual experience and right caudate volume, as well as a marginally significant relationship with left caudate volume. Vertex-wise analyses revealed a significant enlargement of dorsal and anterior portions of the left caudate nucleus, known to have connectivity with executive brain regions, as a function of multilingual expertise. These results suggest that multilingual expertise might exercise a continuous impact on brain structure, and that as additional languages beyond a second are acquired, the additional demands for linguistic and cognitive control result in modifications to brain structures associated with language management processes.
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Of these 67, 33 were multilingual individuals constituting a control group matched to an experimental sample of 34 trainee simultaneous interpreters. The trainees were scanned prior to the onset of their simultaneous interpretation training.
Although this might be considered a marginally significant trend when applying a one-tailed test, we did not have a directional hypothesis on this question. We hope that future work will help to resolve whether putative language-mediated effects on left caudate nucleus structure are sensitive to age of acquisition of a second language.
Abutalebi J (2008) Neural aspects of second language representation and language control. Acta Psychol 128(3):466–478
Abutalebi J, Green∗ DW (2008) Control mechanisms in bilingual language production: neural evidence from language switching studies. Lang Cogn Process 23(4):557–582. https://doi.org/10.1080/01690960801920602
Abutalebi J, Annoni JM, Zimine I, Pegna AJ, Seghier ML, Lee-Jahnke H, Khateb A (2008) Language control and lexical competition in bilinguals: an event-related FMRI study. Cereb Cortex 18(7):1496–1505. https://doi.org/10.1093/cercor/bhm182
Abutalebi J, Della Rosa PA, Gonzaga AK, Keim R, Costa A, Perani D (2013) The role of the left putamen in multilingual language production. Brain Lang 125(3):307–315. https://doi.org/10.1016/j.bandl.2012.03.009
Abutalebi J, Canini M, Della Rosa PA, Sheung LP, Green DW, Weekes BS (2014) Bilingualism protects anterior temporal lobe integrity in aging. Neurobiol Aging 35(9):2126–2133. https://doi.org/10.1016/j.neurobiolaging.2014.03.010
Abutalebi J, Guidi L, Borsa V, Canini M, Della Rosa PA, Parris BA, Weekes BS (2015) Bilingualism provides a neural reserve for aging populations. Neuropsychologia 69:201–210. https://doi.org/10.1016/j.neuropsychologia.2015.01.040
Agostinelli C, Library SLATECCM (2015) wle: Weighted Likelihood Estimation. https://CRAN.R-project.org/package=wle
Bak TH (2016) The impact of bilingualism on cognitive ageing and dementia: finding a path through a forest of confounding variables. Linguist Approaches Biling 6(1–2):205–226. https://doi.org/10.1075/lab.15002.bak
Becker TM, Prat CS, Stocco A (2016) A network-level analysis of cognitive flexibility reveals a differential influence of the anterior cingulate cortex in bilinguals versus monolinguals. Neuropsychologia 85:62–73. https://doi.org/10.1016/j.neuropsychologia.2016.01.020
Berken JA, Gracco VL, Klein D (2017) Early bilingualism, language attainment, and brain development. Neuropsychologia 98:220–227. https://doi.org/10.1016/j.neuropsychologia.2016.08.031
Bialystok E (2011) Reshaping the mind: the benefits of bilingualism. Can J Exp Psychol 65(4):229–235. https://doi.org/10.1037/a0025406
Bialystok E (2017) The bilingual adaptation: how minds accommodate experience. Psychol Bull 143(3):233–262. https://doi.org/10.1037/bul0000099
Bialystok E, Craik FI, Luk G (2012) Bilingualism: consequences for mind and brain. Trends Cogn Sci 16(4):240–250. https://doi.org/10.1016/j.tics.2012.03.001
Burgaleta M, Sanjuan A, Ventura-Campos N, Sebastian-Galles N, Avila C (2016) Bilingualism at the core of the brain. Structural differences between bilinguals and monolinguals revealed by subcortical shape analysis. Neuroimage 125:437–445. https://doi.org/10.1016/j.neuroimage.2015.09.073
Costumero V, Rodriguez-Pujadas A, Fuentes-Claramonte P, Avila C (2015) How bilingualism shapes the functional architecture of the brain: a study on executive control in early bilinguals and monolinguals. Hum Brain Mapp 36(12):5101–5112. https://doi.org/10.1002/hbm.22996
Crinion J, Turner R, Grogan A, Hanakawa T, Noppeney U, Devlin JT, Price CJ (2006) Language control in the bilingual brain. Science 312(5779):1537–1540. https://doi.org/10.1126/science.1127761
Cummine J, Boliek CA (2013) Understanding white matter integrity stability for bilinguals on language status and reading performance. Brain Struct Funct 218(2):595–601. https://doi.org/10.1007/s00429-012-0466-6
Diamond J (2010) The benefits of multilingualism. Science 330(6002):332–333. https://doi.org/10.1126/science.1195067
Dijkstra T, Van Heuven WJB (2002) The architecture of the bilingual word recognition system: from identification to decision. Biling Lang Cogn 5(03):175–197
Garcia-Penton L, Fernandez AP, Iturria-Medina Y, Gillon-Dowens M, Carreiras M (2014) Anatomical connectivity changes in the bilingual brain. Neuroimage 84:495–504. https://doi.org/10.1016/j.neuroimage.2013.08.064
García-Pentón L, Fernández García Y, Costello B, Duñabeitia JA, Carreiras M (2015) The neuroanatomy of bilingualism: how to turn a hazy view into the full picture. Lang Cogn Neurosci 31(3):303–327. https://doi.org/10.1080/23273798.2015.1068944
Gold BT, Johnson NF, Powell DK (2013) Lifelong bilingualism contributes to cognitive reserve against white matter integrity declines in aging. Neuropsychologia 51(13):2841–2846. https://doi.org/10.1016/j.neuropsychologia.2013.09.037
Grahn JA, Parkinson JA, Owen AM (2008) The cognitive functions of the caudate nucleus. Prog Neurobiol 86(3):141–155. https://doi.org/10.1016/j.pneurobio.2008.09.004
Grazioplene RG, Ryman SG, Gray JR, Rustichini A, Jung RE, DeYoung CG (2015) Subcortical intelligence: caudate volume predicts IQ in healthy adults. Hum Brain Mapp 36(4):1407–1416. https://doi.org/10.1002/hbm.22710
Green DW, Abutalebi J (2013) Language control in bilinguals: the adaptive control hypothesis. J Cogn Psychol 25(5):515–530. https://doi.org/10.1080/20445911.2013.796377
Grogan A, Parker-Jones O, Ali N, Crinion J, Orabona S, Mechias ML, Price CJ (2012) Structural correlates for lexical efficiency and number of languages in non-native speakers of English. Neuropsychologia 50(7):1347–1352. https://doi.org/10.1016/j.neuropsychologia.2012.02.019
Hämäläinen S, Sairanen V, Leminen A, Lehtonen M (2017) Bilingualism modulates the white matter structure of language-related pathways. Neuroimage 152(6):249–257
Hervais-Adelman A, Moser-Mercer B, Golestani N (2011) Executive control of language in the bilingual brain: integrating the evidence from neuroimaging to neuropsychology. Front Psychol 2:234. https://doi.org/10.3389/fpsyg.2011.00234
Hervais-Adelman A, Moser-Mercer B, Michel CM, Golestani N (2015) fMRI of simultaneous interpretation reveals the neural basis of extreme language control. Cereb Cortex 25(12):4727–4739. https://doi.org/10.1093/cercor/bhu158
Hervais-Adelman A, Moser-Mercer B, Murray MM, Golestani N (2017) Cortical thickness increases after simultaneous interpretation training. Neuropsychologia 98:212–219. https://doi.org/10.1016/j.neuropsychologia.2017.01.008
Higby E, Kim J, Obler LK (2013) Multilingualism and the Brain. Annu Rev Appl Linguist 33:68–101. https://doi.org/10.1017/S0267190513000081
Hu X, Ackermann H, Martin JA, Erb M, Winkler S, Reiterer SM (2013) Language aptitude for pronunciation in advanced second language (L2) learners: behavioural predictors and neural substrates. Brain Lang 127(3):366–376. https://doi.org/10.1016/j.bandl.2012.11.006
Indefrey P (2006) A meta-analysis of hemodynamic studies on first and second language processing: Which suggested differences can we trust and what do they mean? Lang Learn 56:279–304. https://doi.org/10.1111/j.1467-9922.2006.00365.x
Jenkinson M, Beckmann CF, Behrens TE, Woolrich MW, Smith SM (2012) Fsl. Neuroimage 62(2):782–790. https://doi.org/10.1016/j.neuroimage.2011.09.015
Kaiser A, Eppenberger LS, Smieskova R, Borgwardt S, Kuenzli E, Radue EW, Nitsch C, Bendfeldt K (2015) Age of second language acquisition in multilinguals has an impact on gray matter volume in language-associated brain areas. Front Psychol 6:638. https://doi.org/10.3389/fpsyg.2015.00638
Kroll JF, van Hell JG, Tokowicz N, Green DW (2010) The revised hierarchical model: a critical review and assessment. Biling (Camb Engl) 13(3):373–381. https://doi.org/10.1017/S136672891000009X
Luk G, Pliatsikas C (2016) Converging diversity to unity: commentary on the neuroanatomy of bilingualism. Lang Cogn Neurosci 31(3):349–352. https://doi.org/10.1080/23273798.2015.1119289
Luk G, Bialystok E, Craik FI, Grady CL (2011) Lifelong bilingualism maintains white matter integrity in older adults. J Neurosci 31(46):16808–16813. https://doi.org/10.1523/JNEUROSCI.4563-11.2011
Mechelli A, Crinion JT, Noppeney U, O’Doherty J, Ashburner J, Frackowiak RS, Price CJ (2004) Neurolinguistics: structural plasticity in the bilingual brain. Nature 431(7010):757. https://doi.org/10.1038/431757a
Morgan-Short K, Steinhauer K, Sanz C, Ullman MT (2012) Explicit and implicit second language training differentially affect the achievement of native-like brain activation patterns. J Cogn Neurosci 24(4):933–947. https://doi.org/10.1162/jocn_a_00119
Paap KR, Greenberg ZI (2013) There is no coherent evidence for a bilingual advantage in executive processing. Cogn Psychol 66(2):232–258. https://doi.org/10.1016/j.cogpsych.2012.12.002
Paap KR, Johnson HA, Sawi O (2015) Bilingual advantages in executive functioning either do not exist or are restricted to very specific and undetermined circumstances. Cortex 69:265–278. https://doi.org/10.1016/j.cortex.2015.04.014
Patenaude B, Smith SM, Kennedy DN, Jenkinson M (2011) A Bayesian model of shape and appearance for subcortical brain segmentation. Neuroimage 56(3):907–922. https://doi.org/10.1016/j.neuroimage.2011.02.046
Pliatsikas C, Johnstone T, Marinis T (2014) Grey matter volume in the cerebellum is related to the processing of grammatical rules in a second language: a structural voxel-based morphometry study. Cerebellum 13(1):55–63. https://doi.org/10.1007/s12311-013-0515-6
Pliatsikas C, Moschopoulou E, Saddy JD (2015) The effects of bilingualism on the white matter structure of the brain. Proc Natl Acad Sci USA 112(5):1334–1337. https://doi.org/10.1073/pnas.1414183112
Pliatsikas C, DeLuca V, Moschopoulou E, Saddy JD (2016) Immersive bilingualism reshapes the core of the brain. Brain Struct Funct. https://doi.org/10.1007/s00429-016-1307-9
R Core Team (2015). R: a language and environment for statistical computing. R Foundation for Statistical Computing, Vienna. https://www.R-project.org/. Accessed 19 Apr 2018
Reiterer SM, Hu X, Erb M, Rota G, Nardo D, Grodd W, Ackermann H (2011) Individual differences in audio-vocal speech imitation aptitude in late bilinguals: functional neuro-imaging and brain morphology. Front Psychol 2:271. https://doi.org/10.3389/fpsyg.2011.00271
Ressel V, Pallier C, Ventura-Campos N, Diaz B, Roessler A, Avila C, Sebastian-Galles N (2012) An effect of bilingualism on the auditory cortex. J Neurosci 32(47):16597–16601. https://doi.org/10.1523/JNEUROSCI.1996-12.2012
Sebastian R, Laird AR, Kiran S (2011) Meta-analysis of the neural representation of first language and second language. Appl Psycholinguist 32(4):799–819. https://doi.org/10.1017/S0142716411000075
Smith SM, Nichols TE (2009) Threshold-free cluster enhancement: addressing problems of smoothing, threshold dependence and localisation in cluster inference. Neuroimage 44(1):83–98. https://doi.org/10.1016/j.neuroimage.2008.03.061
Stein M, Federspiel A, Koenig T, Wirth M, Strik W, Wiest R, Dierks T (2012) Structural plasticity in the language system related to increased second language proficiency. Cortex 48(4):458–465. https://doi.org/10.1016/j.cortex.2010.10.007
Stein M, Winkler C, Kaiser A, Dierks T (2014) Structural brain changes related to bilingualism: does immersion make a difference? Front Psychol 5:1116. https://doi.org/10.3389/fpsyg.2014.01116
Stocco A, Lebiere C, Anderson JR (2010) Conditional routing of information to the cortex: a model of the basal ganglia’s role in cognitive coordination. Psychol Rev 117(2):541–574. https://doi.org/10.1037/a0019077
Stocco A, Yamasaki B, Natalenko R, Prat CS (2014) Bilingual brain training: a neurobiological framework of how bilingual experience improves executive function. Int J Biling 18(1):67–92. https://doi.org/10.1177/1367006912456617
Wang J, Zamar R, Marazzi A, Yohai V, Salibian-Barrera M, Maronna R, Konis K (2014) robust: Robust Library. https://CRAN.R-project.org/package=robust. Accessed 19 Apr 2018
Woumans E, Duyck W (2015) The bilingual advantage debate: moving toward different methods for verifying its existence. Cortex 73:356–357. https://doi.org/10.1016/j.cortex.2015.07.012
Zatorre RJ, Fields RD, Johansen-Berg H (2012) Plasticity in gray and white: neuroimaging changes in brain structure during learning. Nat Neurosci 15(4):528–536. https://doi.org/10.1038/nn.3045
Zou L, Ding G, Abutalebi J, Shu H, Peng D (2012) Structural plasticity of the left caudate in bimodal bilinguals. Cortex 48(9):1197–1206. https://doi.org/10.1016/j.cortex.2011.05.022
The authors are grateful to three anonymous reviewers whose helpful suggestions allowed us to substantially improve the manuscript. We also wish to express our gratitude to the staff at the Brain and Behaviour Lab at the University of Geneva and at the Lausanne University Medical Centre who supported the data acquisition.
This work was supported by the Swiss National Science Foundation Grants PP00P3_133701 and PP00P3_163756 awarded to NG.
Conflict of interest
The authors declare that they have no conflict of interest.
All procedures performed were in accordance with the standards of the local research ethics committees of the University Hospitals of Geneva and Lausanne, and with the 1964 Helsinki declaration and its later amendments.
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Hervais-Adelman, A., Egorova, N. & Golestani, N. Beyond bilingualism: multilingual experience correlates with caudate volume. Brain Struct Funct 223, 3495–3502 (2018). https://doi.org/10.1007/s00429-018-1695-0
- Caudate nucleus
- Basal ganglia