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Brain Structure and Function

, Volume 223, Issue 4, pp 1599–1614 | Cite as

Organization of auditory areas in the superior temporal gyrus of marmoset monkeys revealed by real-time optical imaging

  • Masataka Nishimura
  • Makoto Takemoto
  • Wen-Jie Song
Original Article
  • 227 Downloads

Abstract

The prevailing model of the primate auditory cortex proposes a core–belt–parabelt structure. The model proposes three auditory areas in the lateral belt region; however, it may contain more, as this region has been mapped only at a limited spatial resolution. To explore this possibility, we examined the auditory areas in the lateral belt region of the marmoset using a high-resolution optical imaging technique. Based on responses to pure tones, we identified multiple areas in the superior temporal gyrus. The three areas in the core region, the primary area (A1), the rostral area (R), and the rostrotemporal area, were readily identified from their frequency gradients and positions immediately ventral to the lateral sulcus. Three belt areas were identified with frequency gradients and relative positions to A1 and R that were in agreement with previous studies: the caudolateral area, the middle lateral area, and the anterolateral area (AL). Situated between R and AL, however, we identified two additional areas. The first was located caudoventral to R with a frequency gradient in the ventrocaudal direction, which we named the medial anterolateral (MAL) area. The second was a small area with no obvious tonotopy (NT), positioned between the MAL and AL areas. Both the MAL and NT areas responded to a wide range of frequencies (at least 2–24 kHz). Our results suggest that the belt region caudoventral to R is more complex than previously proposed, and we thus call for a refinement of the current primate auditory cortex model.

Keywords

Frequency gradient Optical imaging Primate auditory cortex Tonotopy 

Notes

Acknowledgements

This work was supported by Grant-in-Aid for Scientific Research on Innovative Areas “Adaptive Circuit Shift” (#15H01442) and “Dynamic Regulation of Brain Function by Scrap & Build System” (#17H05749) of the Ministry of Education, Culture, Sports, Science and Technology of Japan, and JSPS Grants (#25290006).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Supplementary material

429_2017_1574_MOESM1_ESM.eps (1.3 mb)
Figure S1. Correlation between t scores and ΔF/F0. Peak t score values and ΔF/F0 in response to the first 1 kHz tone shown in Fig. 1 were measured and plotted across every 10,000 pixels in the time window from 0 to 50 msec after the stimulus onset. (EPS 1281 KB)

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2017

Authors and Affiliations

  1. 1.Department of Sensory and Cognitive Physiology, Graduate School of Medical SciencesKumamoto UniversityKumamotoJapan
  2. 2.Program for Leading Graduate Schools HIGO ProgramKumamoto UniversityKumamotoJapan

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