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Avian stanniocalcin-2 is expressed in developing striated muscle and joints

Anatomy and Embryology volume 211, pages 519–523 (2006)Cite this article

Abstract

The glycoprotein hormone stanniocalcin (STC) has originally been described in the teleost kidney. Since then, STC homologs have been identified in various genomes including human, mouse, rat, Xenopus and zebrafish. In mammals, two STC genes, STC1 and STC2, are known. We cloned a chicken STC homolog to analyze its expression pattern during chick development. Sequence analyses revealed a high sequence similarity of the chicken STC (cSTC) clone to mammalian STC2. Interestingly the expression pattern of cSTC2 largely resembles those of murine STC1: we found expression of cSTC2 in the nephric tubules, in the myocardium, in skeletal muscle cells from the onset of differentiation, and in synovial joint anlagen of the limbs.

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Acknowledgements

We thank Ute Baur, Meike Ast-Dumbach, Susanna Konradi and Ulrike Pein for excellent technical assistance. This work has been supported by the Deutsche Forschungsgemeinschaft (SFB592 to B.C. and M.S.; GRK1104 to B.C. and M.S.) and the European Network of Excellence MYORES (B.C. and M.S)

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  1. Department of Molecular Embryology, Institute of Anatomy and Cell Biology, University of Freiburg, Albertstr. 17, 79104, Freiburg, Germany

    Venugopal Rao Mittapalli, Felicitas Pröls, Ruijin Huang, Bodo Christ & Martin Scaal

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  1. Venugopal Rao Mittapalli
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  2. Felicitas Pröls
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  3. Ruijin Huang
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  4. Bodo Christ
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  5. Martin Scaal
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Correspondence to Martin Scaal.

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Mittapalli, V.R., Pröls, F., Huang, R. et al. Avian stanniocalcin-2 is expressed in developing striated muscle and joints. Anat Embryol 211, 519–523 (2006). https://doi.org/10.1007/s00429-006-0100-6

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  • DOI: https://doi.org/10.1007/s00429-006-0100-6

Keywords

  • Chicken
  • Development
  • Stanniocalcin
  • Muscle
  • Joints