Primary lumbosacral Wilms tumour associated with occult spinal dysraphism


A 4-year-old child presenting with sudden- onset paraplegia and a sacral tumour in association with spina bifida occulta is reported. There were no stigmata of spinal dysraphism at birth. Imaging studies confirmed a sacral tumour with extradural extension up to T10 and spinal dysraphism. The histological features of the extradural and sacral components of the tumour were consistent with a Wilms tumour. The differential diagnosis included a primary sacral teratoma containing Wilms tumour elements or a primary extrarenal Wilms tumour arising in association with a spinal dysraphism. There was no clinical response to chemotherapy or radiotherapy.

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Received: 31 August 1999 / Accepted: 10 December 1999

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Govender, D., Hadley, G., Nadvi, S. et al. Primary lumbosacral Wilms tumour associated with occult spinal dysraphism. Virchows Archiv 436, 502–505 (2000).

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  • Key words Extrarenal nephroblastoma
  • Sacrum
  • Spinal dysraphism
  • Teratoma
  • Wilms tumour