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Primary mismatch repair–deficient prostate cancer can be identified prospectively in prostate biopsies and radical prostatectomies

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References

  1. Abida W, Cheng ML, Armenia J et al (2019) Analysis of the prevalence of microsatellite instability in prostate cancer and response to immune checkpoint blockade. JAMA Oncol 5:471–478. https://doi.org/10.1001/jamaoncol.2018.5801

    Article  PubMed  Google Scholar 

  2. Wyvekens N, Tsai HK, Sholl LM et al (2022) Histopathological and genetic features of mismatch repair-deficient high-grade prostate cancer. Histopathology 80:1050–1060. https://doi.org/10.1111/his.14645

    Article  PubMed  Google Scholar 

  3. van Dessel LF, van Riet J, Smits M et al (2019) The genomic landscape of metastatic castration-resistant prostate cancers reveals multiple distinct genotypes with potential clinical impact. Nat Commun 10:5251. https://doi.org/10.1038/s41467-019-13084-7

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Erson-Omay EZ, Henegariu O, Omay SB et al (2017) Longitudinal analysis of treatment-induced genomic alterations in gliomas. Genome Med 9:12. https://doi.org/10.1186/s13073-017-0401-9

    Article  PubMed  PubMed Central  Google Scholar 

  5. Graham LS, Montgomery B, Cheng HH et al (2020) Mismatch repair deficiency in metastatic prostate cancer: response to PD-1 blockade and standard therapies. PLoS ONE 15:e0233260. https://doi.org/10.1371/journal.pone.0233260

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Authors and Affiliations

  1. Department of Pathology, Indiana University, 350 W 11 St, Room 4080, Indianapolis, IN, 46202, USA

    Andres M. Acosta

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  1. Andres M. Acosta
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AMA diagnosed the cases and wrote this correspondence.

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Correspondence to Andres M. Acosta.

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Acosta, A.M. Primary mismatch repair–deficient prostate cancer can be identified prospectively in prostate biopsies and radical prostatectomies. Virchows Arch (2024). https://doi.org/10.1007/s00428-024-03789-6

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  • DOI: https://doi.org/10.1007/s00428-024-03789-6

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