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A novel primary KIT exon 9 single nucleotide substitution c.1427G>T (p.Ser476Ile) in a gastrointestinal stromal tumor

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References

  1. Hirota S, Isozaki K, Moriyama Y et al (1998) Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science 279:577–580

    Article  CAS  PubMed  Google Scholar 

  2. Fletcher CD, Berman JJ, Corless C et al (2002) Diagnosis of gastrointestinal stromal tumors: a consensus approach. Hum Pathol 33:459–465

    Article  PubMed  Google Scholar 

  3. Miettinen M, Lasota J (2006) Gastrointestinal stromal tumors: pathology and prognosis at different sites. Semin Diagn Pathol 23:70–83

    Article  PubMed  Google Scholar 

  4. Lasota J, Miettinen M (2008) Clinical significance of oncogenic KIT and PDGFRA mutations in gastrointestinal stromal tumours. Histopathology 53:245–266

    Article  CAS  PubMed  Google Scholar 

  5. Martin J, Poveda A, Llombart-Bosch A et al (2005) Deletions affecting codons 557-558 of the c-KIT gene indicate a poor prognosis in patients with completely resected gastrointestinal stromal tumors: a study by the Spanish Group for Sarcoma Research (GEIS). J Clin Oncol 23:6190–6198

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Institute of Pathology and Neuropathology, University Hospital Essen, University of Duisburg-Essen, Hufelandstrasse 55, 45122, Essen, Germany

    Florian Grabellus, Sien-Yi Sheu, Kurt W. Schmid & Karl Worm

  2. Department of Internal Medicine and Cancer Research, University Hospital Essen, University of Duisburg-Essen, Hufelandstrasse 55, 45122, Essen, Germany

    Sebastian Bauer

  3. GenOPath GbR, Heilsbachstrasse 17, 53123, Bonn, Germany

    Norbert Speich

Authors
  1. Florian Grabellus
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  2. Sien-Yi Sheu
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  3. Sebastian Bauer
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  4. Norbert Speich
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  5. Kurt W. Schmid
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  6. Karl Worm
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Correspondence to Florian Grabellus.

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Grabellus, F., Sheu, SY., Bauer, S. et al. A novel primary KIT exon 9 single nucleotide substitution c.1427G>T (p.Ser476Ile) in a gastrointestinal stromal tumor. Virchows Arch 457, 623–625 (2010). https://doi.org/10.1007/s00428-010-0987-4

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  • DOI: https://doi.org/10.1007/s00428-010-0987-4

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