Skip to main content

Advertisement

Log in

Mature cystic teratoma of the ovary with male accessory sexual glands including seminal vesicles, prostatic tissue, and bulbo-urethral glands: a case report

  • Case Report
  • Published:
Virchows Archiv Aims and scope Submit manuscript

Abstract

We present an extremely rare case of a benign cystic ovarian teratoma with structures of male accessory sexual glands. The patient was a 30-year-old woman. A unilocular cystic tumor, measuring 5cm in the largest diameter, was found in her right ovary and was removed. The teratoma contained epidermis, skin appendages, respiratory and intestinal epithelia, cartilage, muscle, and nervous and connective tissue. In addition to these histologically mature tissues, there were nodules with prostatic acini, prostate duct-like structures strongly positive for prostate-specific antigen and acid prostatic phosphatase, structures resembling Cowper’s glands, and seminal vesicles surrounded by fibromuscular stroma. To our knowledge, this is the first case in the English literature describing seminal vesicles associated with prostatic tissue and bulbo-urethral glands in a mature ovarian teratoma.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Bertrand GM (1986) Unique finding of prostatic tissue in a benign cystic ovarian teratoma. Arch Pathol Lab Med 110:683–684

    PubMed  CAS  Google Scholar 

  2. Brumback RA, Brown BS, di Sant’Agnese PA (1985) Unique finding of prostatic tissue in a benign cystic ovarian teratoma. Arch Pathol Lab Med 109:675–677

    PubMed  CAS  Google Scholar 

  3. Halabi M, Oliva E, Mazal PR, Breitenecker G, Young RH (2002) Prostatic tissue in mature cystic teratomas of the ovary: a report of four cases, including one with features of prostatic adenocarcinoma, and cytogenetic studies. Int J Gynecol Pathol 21:261–267

    Article  PubMed  Google Scholar 

  4. Kim KR, Park KH, Kim JW, Cho KJ, Ro JY (2004) Transitional cell metaplasia and ectopic prostatic tissue in the uterine cervix and vagina in a patient with adrenogenital syndrome: report of a case suggesting a possible role of androgen in the histogenesis. Int J Gynecol Pathol 23:182–187

    Article  PubMed  Google Scholar 

  5. McCluggage WG, Ganesan R, Hirschowitz L, Miller K, Rollason TP (2006) Ectopic prostatic tissue in the uterine cervix and vagina: report of a series with a detailed immunohistochemical analysis. Am J Surg Pathol 30:209–215

    Article  PubMed  Google Scholar 

  6. McLachlin CM, Srigley JR (1992) Prostatic tissue in mature cystic teratomas of the ovary. Am J Surg Pathol 16:780–784

    Article  PubMed  CAS  Google Scholar 

  7. Melniker LA, Slavutin LJ (1980) Prostatic tissue in a benign cystic teratoma of the ovary. Diagn Gynecol Obstet 2:139–145

    PubMed  CAS  Google Scholar 

  8. Nogales FF, Vergara E, Medina MT (1995) Prostate in ovarian mature cystic teratoma. Histopathology 26:373–375

    Article  PubMed  CAS  Google Scholar 

  9. Resta L, Marzullo A, Pellegrino M, Rizzi E, Piscitelli D (2004) Male urogenital sinus structures in mature cystic teratomas of the ovary. Report of two cases. Histopathology 45:303–305

    Article  PubMed  CAS  Google Scholar 

  10. Smith CE, Toplis PJ, Nogales FF (1999) Ovarian prostatic tissue originating from hilar mesonephric rests. Am J Surg Pathol 23:232–236

    Article  PubMed  CAS  Google Scholar 

  11. Uzoaru I, Nadimpalli V (1993) Prostate in ovarian teratoma. Am J Surg Pathol 17:531

    Article  PubMed  CAS  Google Scholar 

  12. Vadmal M, Steven I (1996) Prostatic tissue in cystic ovarian teratomas. Hum Pathol 27:428–429

    Article  PubMed  CAS  Google Scholar 

Download references

Conflict of interest statement

We declare that we have no conflict of interest.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Michal Michal.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Shelekhova, K.V., Hejda, V., Kazakov, D.V. et al. Mature cystic teratoma of the ovary with male accessory sexual glands including seminal vesicles, prostatic tissue, and bulbo-urethral glands: a case report. Virchows Arch 452, 109–111 (2008). https://doi.org/10.1007/s00428-007-0546-9

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00428-007-0546-9

Keywords

Navigation