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Sertoli–Leydig cell tumours of the ovary and testis: a CGH and FISH study

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Abstract

We present two malignant cases of Sertoli–Leydig cell tumours (SLCT) of the testis and one ovarian SLCT with benign behaviour. The DNA copy number changes affected chromosome 1, 8, 9p, 10, 11, 12, 16, 19, 22 and X. The present study is the first molecular–cytogenetic analysis of Sertoli–Leydig cell tumours of the testis.

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Acknowledgements

The present case report is part of a study of Leydig cell tumours, supported by the Austrian Cancer Society/Tyrol.

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Authors and Affiliations

  1. Institute of Pathology, Medical University of Innsbruck, Muellerstrasse 44, 6020, Innsbruck, Austria

    I. Verdorfer, D. Horst, A. Höllrigl & G. Mikuz

  2. Institute of Pathology, LKH Klagenfurt, 9020, Klagenfurt, Austria

    H. Rogatsch

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  1. I. Verdorfer
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  2. D. Horst
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  3. A. Höllrigl
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  4. H. Rogatsch
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  5. G. Mikuz
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Correspondence to I. Verdorfer.

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Verdorfer, I., Horst, D., Höllrigl, A. et al. Sertoli–Leydig cell tumours of the ovary and testis: a CGH and FISH study. Virchows Arch 450, 267–271 (2007). https://doi.org/10.1007/s00428-006-0344-9

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  • DOI: https://doi.org/10.1007/s00428-006-0344-9

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