Abstract
Sclerosing hemangioma (SH) with endobronchial growth (SH-EG) is an extremely unusual form of SH. A case of SH-EG in a 47-year-old female is described. She suffered from a productive cough for 4 months. A chest CT scan revealed a well-circumscribed, parenchymal mass with endobronchial lesions continuously extending to the right main bronchus. Right upper sleeve lobectomy was carried out. The tumor was 4.8 × 3.5 cm in size, tan-brown, and elastically soft. It was located in the pulmonary parenchyma of the right upper lobe and continuously extended to the right upper bronchus. Furthermore, the main tumor also spread into segmental bronchi and peripheral bronchioles. Microscopically, the tumor consisted of round to cuboidal cells with papillary and solid patterns, partly showing sclerosis and hemorrhage. For 2.5 years after surgery, the patient has been well without recurrence or metastasis. Florid intrabronchial extension as seen in this case has never been documented in SH. To form an endobronchial component, it seems to be crucial that the parenchymal SH is located adjacent to the bronchus and involves it, followed by the destruction of the bronchial cartilage.
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Devouassoux-Shisheboran M, Nicholson AG, Leslie K, Niho S (2004) Sclerosing hemangioma. In: Travis WD, Brambilla E, Muller-Hermelink HK, Harris CC (eds) World Health Organization of Tumours. Tumours of the lung, pleura, thymus and heart. IARC, Lyon, pp 115–117
Devouassoux-Shisheboran M, Hayashi T, Linnoila RI, Koss MN, Travis WD (2000) A clinicopathologic study of 100 cases of pulmonary sclerosing hemangioma with immunohistochemical studies. Am J Surg Pathol 24:906–916
Devouassoux-Shisheboran M, Fouchardière A, Thivolet-Bèjui F, Sourisseau-Millan, Guerin JC, Travis WD (2004) Endobronchial variant of sclerosing hemangioma of the lung: histological and cytological features on endobronchial material. Mod Pathol 17:252–257
Flieder DB (2004) Papillary adenoma. In: Travis WD, Brambilla E, Muller-Hermelink HK, Harris CC (eds) World Health Organization of Tumours. Tumours of the lung, pleura, thymus and heart. IARC, Lyon, pp 84
Takata T, Koyanagi K, Uchida S, Ohta Y, Sakakibara N, Miyamoto Y (1989) A case of lung metastasis of thyroid cancer with endobronchial polypoid growth. Gan No Rinsho 35:840–844
Kodama T, Watanabe S, Shimosato Y, Yoneyama T, Koide T (1984) Endobronchial polypoid adenocarcinoma of the lung. Histological and ultrastructural studies of five cases. Am J Surg Pathol 8:845–854
Park GY, Lee KY, Yoo CG, Kim YW, Han SK, Shim YS (1999) Bronchoscopic findings of endobronchial vascular lesions in patients with haemoptysis. Respirology 4:401–404
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Wani, Y., Notohara, K., Tsukayama, C. et al. Sclerosing hemangioma with florid endobronchial and endobronchiolar growth. Virchows Arch 450, 221–223 (2007). https://doi.org/10.1007/s00428-006-0339-6
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DOI: https://doi.org/10.1007/s00428-006-0339-6