Skip to main content

Advertisement

SpringerLink
Log in

Expression of epidermal growth factor receptor (EGFR) is frequent in inflammatory bowel disease (IBD)-associated intestinal cancer

  • Letter to the Editor
  • Published:
Virchows Archiv Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. Alexander RJ, Panja A, Kaplan-Liss E, Mayer L, Raicht RF (1995) Expression of growth factor receptor-encoded mRNA by colonic epithelial cells is altered in inflammatory bowel disease. Dig Dis Sci 40:485–494

    Article  PubMed  CAS  Google Scholar 

  2. Chung KY, Shia J, Kemeny NE, Shah M, Schwartz GK, Tse A, Hamilton A, Pan D, Schrag D, Schwartz L, Klimstra DS, Fridman D, Kelsen DP, Saltz LB (2005) Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry. J Clin Oncol 23:1803–1810

    Article  PubMed  CAS  Google Scholar 

  3. Ciardiello F, Tortora G (2003) Epidermal growth factor receptor (EGFR) as a target in cancer therapy: understanding the role of receptor expression and other molecular determinants that could influence the response to anti-EGFR drugs. Eur J Cancer 39:1348–1354

    Article  PubMed  CAS  Google Scholar 

  4. Cunningham D, Humblet Y, Siena S, Khayat D, Bleiberg H, Santoro A, Bets D, Mueser M, Harstrick A, Verslype C, Chau I, Van Cutsem E (2004) Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med 351:337–345

    Article  PubMed  CAS  Google Scholar 

  5. Goldstein NS, Armin M (2001) Epidermal growth factor receptor immunohistochemical reactivity in patients with American Joint Committee on Cancer stage IV colon adenocarcinoma: implications for a standardized scoring system. Cancer 92:1331–1346

    Article  PubMed  CAS  Google Scholar 

  6. O’Dwyer PJ, Benson AB (2002) Epidermal growth factor receptor-targeted therapy in colorectal cancer. Semin Oncol 29:10–17 (Suppl)

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. AP-HP, Hôpital Saint-Antoine, Service d’Anatomie et Cytologie Pathologiques, 184, rue du Faubourg Saint-Antoine, 75571, Paris Cedex 12, France

    Magali Svrcek & Jean-François Fléjou

  2. Université Paris6, Faculté de Médecine Pierre et Marie Curie, Paris, France

    Magali Svrcek, Jacques Cosnes, Emmanuel Tiret, Malika Bennis, Yann Parc & Jean-François Fléjou

  3. Inserm, U762, CEPH, Paris, France

    Magali Svrcek & Jean-François Fléjou

  4. AP-HP, Hôpital Saint-Antoine, Service de Gastroentérologie et Nutrition, 184, rue du Faubourg Saint-Antoine, 75571, Paris Cedex 12, France

    Jacques Cosnes

  5. AP-HP, Hôpital Saint-Antoine, Service de Chirurgie Viscérale, 184, rue du Faubourg Saint-Antoine, 75571, Paris Cedex 12, France

    Emmanuel Tiret, Malika Bennis & Yann Parc

Authors
  1. Magali Svrcek
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Jacques Cosnes
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Emmanuel Tiret
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Malika Bennis
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Yann Parc
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Jean-François Fléjou
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Magali Svrcek.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Svrcek, M., Cosnes, J., Tiret, E. et al. Expression of epidermal growth factor receptor (EGFR) is frequent in inflammatory bowel disease (IBD)-associated intestinal cancer. Virchows Arch 450, 243–244 (2007). https://doi.org/10.1007/s00428-006-0338-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00428-006-0338-7

Keywords

Search

Navigation