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Developmental expression of cardiac myosin-binding protein C in Xenopus

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Abstract.

We have isolated the Xenopus homologue of cardiac myosin-binding protein C (cMyBP-C) and describe its expression during early embryogenesis. cMyBP-C is expressed in both somites and heart at the time these tissues differentiate. Expression in the somites declines in older tadpoles. There is a high degree of conservation in residues where mutations causing hypertrophic cardiomyopathy have been identified in humans.

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  1. Lawson Health Research Institute, 268 Grosvenor Street, Departments of Paediatrics, Physiology, and Zoology, University of Western Ontario, London, Ontario N6A 4V2, Canada, , , , ,

    Li-Juan Duan, Miranda E. George & Thomas A. Drysdale

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  1. Li-Juan Duan
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  2. Miranda E. George
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  3. Thomas A. Drysdale
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Duan, LJ., George, M.E. & Drysdale, T.A. Developmental expression of cardiac myosin-binding protein C in Xenopus . Dev Genes Evol 212, 47–49 (2002). https://doi.org/10.1007/s00427-001-0199-7

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  • DOI: https://doi.org/10.1007/s00427-001-0199-7

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